Results 11 to 20 of about 137,019 (343)
European Psychiatry, 2023 Introduction Cannabis (aka marijuana) is the most frequently consumed illicit substance worldwide, and a subset of frequent cannabis smokers (up to 30%) develop dependence.
R. Sharma +4 more
doaj +2 more sources
Symptomology Associated with in Utero Exposures to Polysubstance in an Appalachian Population [PDF]
Marshall Journal of Medicine, 2019 Neonatal abstinence syndrome (NAS) is seen as a very high rate at our institution in Huntington, West Virginia, and the majority of exposures are polysubstance in nature. Polysubstance can have different meaning for each region.
Will Lester +5 more
doaj +2 more sources
Clinical Manifestations of the Opiate Withdrawal Syndrome [PDF]
International Journal of Biomedicine, 2015 Currently, substance abuse is one of the most serious problems facing our society. The aim of this study was to investigate the clinical manifestations of the opiate withdrawal syndrome (OWS).
Faniya Shigakova
doaj +2 more sources
Effectiveness and Safety of Haloperidol Add-on Methadone in Acute Opium Withdrawal Symptoms of Opioid-dependent Patients: A Double-blind Randomized Placebo-controlled Clinical Trial [PDF]
Addiction and Health, 2021 Background: The aim of this double-blind clinical trial was to evaluate the efficacy and safety of haloperidol on acute opioid withdrawal symptoms. Methods: In this randomized double-blind clinical trial, fifty-two eligible patients were assigned to two ...
Fattaneh Ghaderi-Bafti +5 more
doaj +1 more source
Is Clonidine Useful for the Management of Tramadol-induced Withdrawal Syndrome? [PDF]
Asia Pacific Journal of Medical Toxicology, 2022 Dear Editor-in-chiefTramadol is a synthetic opioid with non-opioid effects. It has a low affinity to opioid receptors and inhibits re-uptake of norepinephrine and serotonin in synapses [1- 5].
Mohammad Majidi +2 more
doaj +1 more source
A mathematical model of reward-mediated learning in drug addiction [PDF]
Chaos 32, 021102 (2022), 2022 Substances of abuse are known to activate and disrupt neuronal circuits in the brain reward system. We propose a simple and easily interpretable dynamical systems model to describe the neurobiology of drug addiction that incorporates the psychiatric concepts of reward prediction error (RPE), drug-induced incentive salience (IST), and opponent process ...
arxiv +1 more source
Frontiers in Psychiatry, 2023 Introduction Alcohol use disorder (AUD) is the most prevalent substance use disorder (SUD) globally. In 2019, AUD affected 14.5 million Americans and contributed to 95,000 deaths, with an annual cost exceeding 250 billion dollars.
C. Goldfine +7 more
semanticscholar +1 more source
Frontiers in Pediatrics, 2021 Objective: To investigate the outcomes associated with the implementation of a neonatal abstinence syndrome (NAS) treatment algorithm utilizing dual therapy with morphine sulfate and clonidine in a level four neonatal intensive care unit (NICU).Study ...
Mohammad Y. Bader +11 more
doaj +1 more source
Efficacy of Lofexidine in the Outpatient Management of Tramadol Withdrawal Syndrome
International Journal of Medical Toxicology and Forensic Medicine, 2020 Tramadol is recognized as an opioid with non-opiate properties. It has a low affinity for opioid receptors and prevents reabsorption of norepinephrine and serotonin at synapses. It also increases the level of Gamma Aminobutyric Acid (GABA) in the central
Mohammad Majidi , Solmaz Nekoueifard
doaj +1 more source
JMIR Formative Research, 2022 BackgroundThe cessation of opioid use can cause withdrawal symptoms. People often continue opioid misuse to avoid these symptoms. Many people who use opioids self-treat withdrawal symptoms with a range of substances.
Alexander Preiss +3 more
doaj +1 more source