Results 11 to 20 of about 107,326 (259)

A Retrospective Review Following the Addition of Clonidine to a Neonatal Abstinence Syndrome Treatment Algorithm

Frontiers in Pediatrics, 2021
Objective: To investigate the outcomes associated with the implementation of a neonatal abstinence syndrome (NAS) treatment algorithm utilizing dual therapy with morphine sulfate and clonidine in a level four neonatal intensive care unit (NICU).Study ...
Mohammad Y. Bader, Mohammad Y. Bader, Nahla Zaghloul, Nahla Zaghloul, Ashley Repholz, Nadia Nagy, Nadia Nagy, Mohamed N. Ahmed, Mohamed N. Ahmed, Leslie Thompson, Ranjit I. Kylat, Ranjit I. Kylat   +11 more
doaj   +1 more source

Efficacy of Lofexidine in the Outpatient Management of Tramadol Withdrawal Syndrome

International Journal of Medical Toxicology and Forensic Medicine, 2020
Tramadol is recognized as an opioid with non-opiate properties. It has a low affinity for opioid receptors and prevents reabsorption of norepinephrine and serotonin at synapses. It also increases the level of Gamma Aminobutyric Acid (GABA) in the central
Mohammad Majidi , Solmaz Nekoueifard
doaj   +1 more source

Inhibition of NMDA receptors by agmatine is followed by GABA/glutamate balance in benzodiazepine withdrawal syndrome

Beni-Suef University Journal of Basic and Applied Sciences, 2021
Background Drug withdrawal syndrome occurs due to abrupt cessation of an addictive substance. Dependence to diazepam can be manifested by withdrawal syndrome which may include symptoms such as irritability, psychosis, sleep disturbance, seizures, mood ...
Hira Rafi, Hamna Rafiq, Muhammad Farhan
doaj   +1 more source

Using Named Entity Recognition to Identify Substances Used in the Self-medication of Opioid Withdrawal: Natural Language Processing Study of Reddit Data

JMIR Formative Research, 2022
BackgroundThe cessation of opioid use can cause withdrawal symptoms. People often continue opioid misuse to avoid these symptoms. Many people who use opioids self-treat withdrawal symptoms with a range of substances.
Alexander Preiss, Peter Baumgartner, Mark J Edlund, Georgiy V Bobashev   +3 more
doaj   +1 more source

Cognitive and Mental Health Predictors of Withdrawal Severity During an Active Attempt to Cut Down Cannabis Use

Frontiers in Psychiatry, 2018
A milestone in cannabis research is the establishment of a clinically relevant cannabis withdrawal syndrome, yet little is known about the underlying mechanisms.
Janna Cousijn, A. C. K. van Duijvenvoorde, A. C. K. van Duijvenvoorde   +2 more
doaj   +1 more source

Current Concepts on Drug Abuse and Dependence [PDF]

, 2015
Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza, Bălălău, Cristian, Ciobanu, Anne-Marie, Cobani, Oana Denisa, Negrei, Carolina, Vlăsceanu, Ana Maria   +5 more
core   +3 more sources

Characterization of cannabis withdrawal symptoms and serum levels of neurotransmitters among cannabis-dependent smokers during sustained abstinence within a controlled residential environment

European Psychiatry, 2023
Introduction Cannabis (aka marijuana) is the most frequently consumed illicit substance worldwide, and a subset of frequent cannabis smokers (up to 30%) develop dependence.
R. Sharma, S. K. Tikka, A. R. Bhute, P. Dhamija, B. K. Bastia   +4 more
doaj   +1 more source

DSM-5 criteria for substance use disorders: recommendations and rationale. [PDF]

, 2013
Since DSM-IV was published in 1994, its approach to substance use disorders has come under scrutiny. Strengths were identified (notably, reliability and validity of dependence), but concerns have also arisen.
Auriacombe, Marc, Borges, Guilherme, Bucholz, Kathleen, Budney, Alan, Compton, Wilson M, Crowley, Thomas, Grant, Bridget F, Hasin, Deborah S, Ling, Walter, O'Brien, Charles P, Petry, Nancy M, Schuckit, Marc   +11 more
core   +1 more source

The relationship between addiction and hikikomori tendencies: a case-control study

Frontiers in Psychiatry, 2023
AimThe present study examined the relationship between addiction and hikikomori (extreme social withdrawal) symptoms.MethodA group of clinically referred addiction patients (n = 31) and a group of age- and gender-matched non-clinical controls (n = 34 ...
Peter Muris, Veerle van de Pasch, Veerle van de Pasch, Janno van Kessel, Josine Peet   +4 more
doaj   +1 more source

Case Report: Treatment of Kratom Use Disorder With a Classical Tricyclic Antidepressant

Frontiers in Psychiatry, 2021
Kratom or Mitragyna speciosa (Korth.) is an evergreen tree of the coffee family native to South-East Asia and Australasia. It is used by locals recreationally to induce stimulant and sedative effects and medically to soothe pain and opiate withdrawal ...
Alessandro E. Vento, Alessandro E. Vento, Simone de Persis, Sergio De Filippis, Fabrizio Schifano, Flavia Napoletano, John M. Corkery, Georgios D. Kotzalidis, Georgios D. Kotzalidis   +8 more
doaj   +1 more source