Results 61 to 70 of about 123,595 (337)
To achieve accuracy in studying the patterns of loss of midbrain dopamine-containing neurons in Parkinson's disease, we used compartmental patterns of calbindin D(28K) immunostaining to subdivide the substantia nigra with landmarks independent of the ...
P. Damier+3 more
semanticscholar +1 more source
Objectives Prospective studies demonstrated that essential tremor is a risk factor for Parkinson's disease. Identifying clinical markers for conversion from essential tremor to essential tremor‐Parkinson's disease would be of considerable value. Rest tremor can be present in advanced essential tremor and may be a harbinger of conversion. We examined (1)
Elan D. Louis+3 more
wiley +1 more source
Current clinical protocols for fetal cell transplantation for Parkinson's disease (PD) have focused on restoring dopamine in the striatum. However, there are now a number of human transplant recipients who have had robust innervation of the striatum by ...
Philip A. Starr M.D.,Ph.D.+3 more
doaj +1 more source
Diffusion Kurtosis Imaging for Detection of Early Brain Changes in Parkinson's Disease
We aimed to evaluate microscale changes in the bilateral red nucleus and substantia nigra of patients with Parkinson's disease (PD) using diffusion kurtosis imaging (DKI).
Jitian Guan+17 more
doaj +1 more source
Similar Roles of Substantia Nigra and Ventral Tegmental Dopamine Neurons in Reward and Aversion
Dopamine neurons in the ventral tegmental area (VTA) are implicated in affective functions. However, it is unclear to what extent dopamine neurons in substantia nigra pars compacta (SNc) play such roles.
A. Ilango+5 more
semanticscholar +1 more source
What does it mean? Translating anatomical language to engage public audiences
Abstract The language of anatomy, with its roots in Ancient Greek and Roman languages, is complex and unfamiliar to many. Its complexity creates a significant barrier to public knowledge and understanding of anatomy—many members of the public find themselves asking “what does it mean?”, and this can manifest as poor health literacy and outcomes.
Kat A. Sanders, Adam M. Taylor
wiley +1 more source
Beitrag zur vergleichenden Anatomie der Substantia nigra, des Corpus Luysii und der Zona incerta. (Fortsetzung.) [PDF]
Torata Sano
openalex +2 more sources
Recent findings indicate that mitochondria‐associated membranes (MAMs), where the endoplasmic reticulum directly contacts the mitochondria, are a novel microdomain essential for cellular homeostasis, including proteostasis. We summarize the disruption of protein homeostasis and MAM alteration in neurodegenerative diseases, then discuss challenges and ...
Seiji Watanabe, Koji Yamanaka
wiley +1 more source
Low levels of astroglial markers in Parkinson’s disease: relationship to α-synuclein accumulation
Although gliosis is a normal response to brain injury, reports on the extent of astrogliosis in the degenerating substantia nigra in Parkinson’s disease (PD) are conflicting.
Junchao Tong+8 more
doaj
MR imaging of the substantia nigra at 7 T enables diagnosis of Parkinson disease.
PURPOSE To evaluate the anatomy of the substantia nigra (SN) in healthy subjects by performing 7-T magnetic resonance (MR) imaging of the SN, and to prospectively define the accuracy of 7-T MR imaging in distinguishing Parkinson disease (PD) patients ...
M. Cosottini+7 more
semanticscholar +1 more source