Results 81 to 90 of about 73,544 (253)
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) is clinically heterogeneous, with variable progression rates that complicate clinical trial design. The data‐driven diffuse malignant (DM), intermediate (IM), and mild‐motor predominant (MMP) subtyping model has prognostic value but lacks disease duration–specific thresholds for prospective use in disease ...
Ahmed Negida +4 more
wiley +1 more source
EFFECT OF THE NUCLEUS CAUDATUS AND THE DOPAMINERGIC NEURON ON ACUPUNCTURE ANALGESIA
针刺研究, 1980 The present paper is divided into two parts.The nucleus caudatus has been described briefly in the first part.(1) The nervous circuity ofnucleus eaudatus:The pars compacta of substantia nigra contains the cell body of one of the maindopamine(DA) fiber ...
Sun Deyu
doaj +2 more sources
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) progression is highly heterogeneous, complicating clinical management and prognostication. While machine learning models have been developed using research datasets such as Parkinson's Precision Medicine Initiative (PPMI) and Parkinson's Disease Biomarkers Program (PDBP), their clinical translatability is ...
Xuehua Ye +9 more
wiley +1 more source
The Incidence of Sensorineural Hearing Loss Diagnoses in People with and without Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) and sensorineural hearing loss (SNHL) are both prevalent conditions among older adults. Although increasing number of studies have investigated SNHL as a risk factor for PD, it is not well known how diagnosed PD affects the likelihood of SNHL diagnosis.
Kaisa Hokkinen +4 more
wiley +1 more source
Volumetric and Intrastructural Characterization of the Substantia Nigra Using Optimized Synthetic MR Images Derived From Quantitative T1 Maps at 3 T [PDF]
NMR BiomedAutomated segmentation using the NextBrain atlas and synthetic MRI effectively overcomes systematic age‐related biases observed in manual delineation of the substantia nigra. A novel qT1‐based synthetic contrast utilizing signal‐increased pseudo‐proton spin density (pPSD) provides improved intrastructural separation of nigral subregions (SNpc and SNpr)
von Erdmannsdorff L +5 more
europepmc +2 more sources
PREDICT‐PD: A Two‐Stage Approach to Early Identification of Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.
Sasivimol Virameteekul +9 more
wiley +1 more source
Effect of electroacupuncture on brain-gut oxidative stress in Parkinson’s disease mice
针刺研究ObjectiveTo observe the effect of electroacupuncture （EA） on behavior， oxidative stress factors in colon and substantia nigra of Parkinson’s disease （PD） mice， so as to explore the mechanism of EA in treating PD.MethodsC57BL/6 mice were randomly divided ...
LIU Fan +4 more
doaj +2 more sources
Movement Disorders Clinical Practice, EarlyView.Abstract Background Freezing of gait (FoG) belongs to most pressing unmet symptoms in the treatment of Parkinson's disease. Objectives To explore whether combined subthalamic and nigral (STN + SNr) deep brain stimulation improves FoG compared with optimized STN stimulation alone; to identify clinical variables associated with therapeutic response ...
Daniel Weiss +29 more
wiley +1 more source
针刺研究, 2014 Objective To observe the effect of electroacupuncture(EA)on superoxide(SOD),glutathione peroxidase(GSH-Px)activity,contents of glutathione(GSH)and malondiadehyde(MDA),and expression of tyrosine hydroxylase(TH)and apoptosis of Dopaminergic(DA)neurons in ...
LI Jing +4 more
doaj +2 more sources