Results 121 to 130 of about 67,257 (300)
Substituent effect on TADF properties of 2-modified 4,6-bis(3,6-di-tert-butyl-9-carbazolyl)-5-methylpyrimidines. [PDF]
Beilstein J Org Chem, 2022 Fiodorova I +4 more
europepmc +1 more source
Substituent effect on the redox potential of substituted(aryl)(2-nitrobenzo [b]thiophen-3-yl) amines
, 2001 The electronic effect of some meta- or para-substituents on the reduction of the title compounds has been investigated. The reversible reduction potential values of these compounds have been evaluated by cyclic voltammetry at a mercury electrode in 0.1 M
Domenica Tonelli +13 more
core +1 more source
A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
Advanced Science, EarlyView.A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
Química NovaHerein, we propose an interdisciplinary experiment for undergraduate course that involves concepts of organic and physical chemistry. Firstly, we propose the synthesis of three nitrophenyl acetates, varying the substituent position.
Valmir B. Silva, Elisa S. Orth
doaj +1 more source
Molecular basis of LFER : theoretical study of polar substituent effect in aliphatic series
, 2007 The nature of inductive substituent effect on the gas phase acidity of several series of aliphatic carboxylic acids with rigid molecular skeletons was analyzed using the recently proposed quantum chemical approach based on the theory of proton affinity ...
Ponec, Robert +2 more
core +1 more source
Photocatalytic Synthesis of Pentafluorosulfanyl Ketones, Acetals, and BCP Motifs Utilizing SF6
Advanced Science, EarlyView.A photocatalytic single electron reduction strategy is reported for the activation and valorization of sulfur hexafluoride (SF6), a potent greenhouse gas. Under mild conditions, SF6 is reduced to generate pentafluorosulfanyl (SF5) radicals, enabling direct access to pentafluorosulfanyl ketones, acetals, and BCP motifs.
Chen‐Hui Jiang +11 more
wiley +1 more source
, 2016 The synthesis and examination of a systematic series of 5-substituted 2-keto oxazoles as inhibitors of fatty acid amide hydrolase (FAAH) defined a fundamental substituent effect that led to the discovery of inhibitors with Ki's as low as 400 pM.
Dale L. Boger (1306542) +2 more
core +1 more source
Advanced Science, EarlyView.A new generation of high‐precision fluorescent probes based on the lysosomal characteristics in tumor metabolic reprogramming and overexpressed tumor markers. The probe (CN‐D‐GGT) selectively label cancer cells in co‐culture systems and distinguish tumor lesions from inflamedand normal tissues in vivo, enabling precise tumor imaging.
Yang Shen +6 more
wiley +1 more source
Substituent effects on imidazole derivatives
, 2010 Üç bölümden oluşan bu tez 1,3-disübstitüye imidazolyum bromürlerin (1-5) sentezi ve katalitik özellikleriyle ilgilidir. Birinci bölüm imidazollere ait temel bilgiler, önemi ve kullanımları hakkında kısa bir derlemedir. İkinci bölümde deneysel veriler ayrıntılı bir biçimde açıklanmıştır. Üçüncü bölüm 1,3-disübstitüye imidazolyum tuzlarının sentezi, yapı
openaire +2 more sources
Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source