Results 141 to 150 of about 134,654 (299)

Substituent Effect in the First Excited Triplet State of Monosubstituted Benzenes. [PDF]

ACS Omega, 2020
Dobrowolski JC, Karpińska G.
europepmc   +1 more source

Substrate‐Affinitive P‐Type Azapolycyclic Photosensitizer for Chemoselective Nitrilization Under Mild Conditions

Advanced Science, EarlyView.
We developed a series of quinoxalinoquinoxaline (QQ) photosensitizers featuring high and tunable excited‐state reduction potentials (E(PC•+/PC*) = –1.76 to –2.05 V vs. SCE). Their hydrogen‐bonding interaction with carbonyl substrates enables selective single‐electron transfer events for selective nitrilization of 1° amides, offering a tunable ...
Seongwoo Bae, Dongwook Kim, Jinwoo Kim
wiley   +1 more source

Substituent effect on inter-ring interaction in paracyclophanes. [PDF]

Mol Divers, 2020
Majerz I, Dziembowska T.
europepmc   +1 more source

Hyperconjugative stabilization of silicenium ions: kinetics of hydride abstractions from .beta.-element-substituted silanes [PDF]

, 1993
Basso, Nils, Goers, Solvig, Mayr, Herbert, Popowski, Eckhard   +3 more
core   +1 more source

Bidirectional Photoswitching of a Tailored Azobenzene with Red and Far‐Red Light Involving Triplet Sensitization in an Aqueous System

Advanced Science, EarlyView.
The action spectrum of a tailored azobenzene is shifted toward bio‐optical window through the chemical modification of its singlet and triplet energy levels. Consequently, the bidirectional photo‐switching of azobenzene in physiological conditions is achieved when excited by red and far‐red light, which offers greater tissue penetration.
Mila Miroshnichenko, Helen Hölzel, Edvinas Orentas, Karolis Kazlauskas, Pedro Ferreira, Fabienne Dumoulin, Carles Alcaide, Miquel Solà, Roger Bresolí‐Obach, Santi Nonell, Pankaj Bharmoria, Kasper Moth‐Poulsen   +11 more
wiley   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

Substituent Effect on Porphyrin Film-Gas Interaction by Optical Waveguide: Spectrum Analysis and Molecular Dynamic Simulation. [PDF]

Materials (Basel), 2020
Kari N, Zannotti M, Mamtmin G, Giovannetti R, Minofar B, Řeha D, Maimaiti P, Kutilike B, Yimit A.   +8 more
europepmc   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Heterogeneous Visible‐Light Photocatalysis in Continuous‐Flow: A Synergistic Strategy for Challenging Trifluoromethylation of α, α‐Diaryl Allylic Alcohols via 1,2‐aryl Migration

Advanced Science, EarlyView.
A continuous‐flow photocatalytic strategy is presented for the efficient synthesis of β‐trifluoromethyl ketones under visible light. Using a recyclable solid photocatalyst and an inexpensive CF3 source, the method enables rapid reactions, easy scale‐up, and smooth integration into multistep flow synthesis of bioactive molecules.
Peiwen Liu, Weiping Zhu, Xuhong Qian, Fang Zhao   +3 more
wiley   +1 more source

Localizable Fluorescent Metal Ion Indicators With Tunable Colors

Advanced Science, EarlyView.
A modular platform enables the generation of fluorescent metal ion indicators with tunable emission colors and precise subcellular localization. Conjugation to self‐labeling proteins yields bright, color‐tunable potassium probes that permit wash‐free live‐cell imaging, revealing dynamic potassium efflux in stimulated neurons.
Ming‐Ming Wang, De‐en Sun, Klara Gries, Kai Johnsson   +3 more
wiley   +1 more source