Results 71 to 80 of about 1,384,644 (306)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Microscopic analysis of the chemical reaction between Fe(Te,Se) thin films and underlying CaF$_2$

, 2012
To understand the chemical reaction at the interface of materials, we performed a transmission electron microscopy (TEM) observation in four types of Fe(Te,Se) superconducting thin films prepared on different types of substrates: CaF2 substrate, CaF2 ...
A Ichinose, A Maeda, Bellingeri E, F Nabeshima, Han Y, I Tsukada, M Hanawa, Mele P, Ogino H, Seiki Komiya, T Akiike, Y Imai   +11 more
core   +1 more source

Graphene on the C-terminated SiC (000 $\bar{1}$) surface: An ab initio study [PDF]

, 2009
The atomic and electronic structures of a graphene layer on top of the $(2\times2)$ reconstruction of the SiC (000$\bar{1}$) surface are studied from ab initio calculations. At variance with the (0001) face, no C bufferlayer is found here.
F. Hiebel, F. Hiebel, F. Varchon, J.-Y. Veuillen, L. Magaud, P. Mallet   +5 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Spatial distribution of Gaussian fluctuations of the molecular field and magnetization in the pyramid-like Ising nanoscopic system interacting with the substrate

, 2009
We study thermodynamic properties of an Ising model of a ferromagnetic nanoscopic pyramid deposited onto a ferromagnetic bulk substrate. The influence of the interaction between the pyramid and the substrate is calculated in terms of the equilibrium ...
Bland, Borkowski, Hirjibehedin, Hoffmann, Jacyna-Onyszkiewicz, Jamet, Kaiser, Kosiorek, Kosiorek, L.S. Borkowski, Müller, Ness, Onyszkiewicz, Onyszkiewicz, Onyszkiewicz, Onyszkiewicz, Schmid, Skomski, Z. Jacyna-Onyszkiewicz   +18 more
core   +1 more source

Applying laboratory thermal desorption data in an interstellar context: sublimation of methanol thin films [PDF]

, 2009
Methods by which experimental measurements of thermal desorption can be applied in astrophysical environments have been developed, using the sublimation of solid methanol as an example.
Acharyya, Amandeep S. Bolina, Attard, Ayotte, Bahr, Bennett, Bolina, Brown, Brown, Christmann, Collings, Collings, Collings, Dartois, Dawes, Fraser, Fraser, Gong, Gálvez, Günster, Harris, Herbst, Hrbek, Jenniskens, Kimmel, King, Kouchi, Mark P. Collings, Markwick, Martin R. S. McCoustra, Maté, Nagaoka, Nishimura, Outka, Palmer, Peremans, Peremans, Pontoppidan, Pontoppidan, Pratt, Rendulic, Roberts, Rui Chen, Safarik, Sandford, Sexton, Sexton, Sexton, Simon D. Green, Smith, Sneh, Souda, Thrower, Tielens, Tielens, Torrie, Viti, Viti, Wang, Watanabe, Wendy A. Brown, Wolff, Woodruff, Wu, Zhang   +64 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The strong influence of substrate conductivity on droplet evaporation [PDF]

, 2009
We report the results of physical experiments that demonstrate the strong influence of the thermal conductivity of the substrate on the evaporation of a pinned droplet.
B. R. DUFFY, Deegan, Fang, G. J. DUNN, K. SEFIANE, Lebedev, Lide, Monteith, Perry, Popov, Poulard, Raznjevic, Reid, S. DAVID, S. K. WILSON, Tennent   +15 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The influence of concrete substrate moisture condition on the tensile pull-off strength of protective coatings

MATEC Web of Conferences, 2018
A range of different surface coatings are available for the protection of concrete surfaces, typically aimed at reducing the ingress of deleterious substances into the concrete and providing adequate aesthetic appeal on patch-repaired elements.
Kay Sean, Beushausen Hans
doaj   +1 more source