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Role of calcium in synaptosomal substrate oxidation

Archives of Biochemistry and Biophysics, 1988
The effect of veratridine-mediated depolarization on rat brain synaptosomal respiration in the presence and absence of calcium was investigated. Studies on respiration were performed employing three different pretreatments of the synaptosomes which attempted to deplete endogenous substrates.
T B, Patel, D, Sambasivarao, H M, Rashed
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Substrate Oxidation

2010
The immediate source of energy for muscle contraction is provided by the hydrolysis of adenosine triphosphate (ATP). However, muscle ATP stores are not large and would be consumed in only a few seconds of high-intensity exercise if they were not quickly replenished.
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Substrate Specificity of a Nitroalkane-Oxidizing Enzyme

Archives of Biochemistry and Biophysics, 1999
The flavoprotein nitroalkane oxidase from Fusarium oxysporum catalyzes the oxidation of nitroalkanes to aldehydes with production of hydrogen peroxide and nitrite. The substrate specificity of the FAD-containing enzyme has been determined as a probe of the active site structure.
G, Gadda, P F, Fitzpatrick
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Isoform-Selective Substrates of Nitric Oxide Synthase

Journal of Medicinal Chemistry, 2003
Because of the double-edged nature of NO, the development of isoform-selective NOS substrates is a highly desirable goal. Given the striking similarity in the heme active sites of the three NOS isoforms, it presents an challenging problem. Several N-aryl-N'-hydroxyguanidines have recently been shown as substrates that are selective for iNOS over nNOS ...
Qiang, Jia   +6 more
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Engineering Oxide Epitaxy beyond Substrate Constraint

Nano Letters
Orientation engineering is a crucial aspect of thin film growth, and it is rather challenging to engineer film epitaxy beyond the substrate constraint. Guided by density functional theory calculations, we use SrRuO3 (SRO) as a buffer layer and successfully deposit [111]-oriented CoFe2O4 (CFO) on [001]-, [110]-, and [111]-oriented SrTiO3 (STO ...
Mingqiang Cheng   +6 more
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Bypassing Biocatalytic Substrate Limitations in Oxidative Dearomatization Reactions by Transient Substrate Mimicking

Organic Letters, 2019
Enzymatic oxidative dearomatization is an efficient way to generate chiral molecules from simple arenes. One example is the flavin-dependent monooxygenase SorbC involved in sorbicillinoid biosynthesis. However, SorbC requires a long-chain keto substituent at its phenolic substrate, thus preventing its application beyond the synthesis of natural ...
Tobias M. Milzarek   +10 more
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Effect of elevated substrates on substrate oxidation in normal and diabetic aorta

Acta Physiologica Scandinavica, 1983
The influence of elevated substrates (glucose, β‐hydroxybutyrate and palmitate) on the gated. The oxidation of 14C‐glucose to 14CO2 was depressed in diabetic aorta at a glucose concentration of 5.6 mM in the incubation medium. The glucose oxidation in normal and diabetic aorta was not affected by raising the glucose concentration of the medium to 22.2 ...
H H, Dahlkvist, H J, Arnqvist, K, Norrby
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Substrate hole current and oxide breakdown

Applied Physics Letters, 1986
It is known that when an n-channel metal-oxide-semiconductor field-effect transistor is biased with a high positive gate voltage, a hole current appears in the substrate cathode. Recent experiments indicate that the holes are generated within the oxide. We show that this hole generation mechanism is linked to oxide time-dependent breakdown.
I. C. Chen   +4 more
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The endogenous substrate for nuclear oxidative phosphorylation

Archives of Biochemistry and Biophysics, 1969
Abstract Inosine increased both the rate and level of ATP synthesis in isolated rat thymus nuclei. Adenine was rapidly incorporated into nuclear ATP but the hypoxanthine moiety of inosine was incorporated only slightly. Inosine enhanced incorporation of adenine into nuclear ATP. It was concluded that the effect of inosine resided in the ribose part.
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Planar oxidation of strained silicon substrates

Journal of Materials Research, 2001
We report here on a series of experiments in which relatively low levels of in-plane bending strain were applied to oxidizing silicon substrates. These were found to result in significant decreases in oxide thickness in the ultrathin oxide regime.
M-T. Lin, R. J. Jaccodine, T. J. Delph
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