Asynchronous mouse embryo polarization leads to heterogeneity in cell fate specification [PDF]
The first lineage allocation in mouse and human embryos separates the inner cell mass (ICM) from the outer trophectoderm (TE). This symmetry-breaking event is executed through polarization of cells at the 8 cell stage and subsequent asymmetric divisions,
Adiyant Lamba +11 more
doaj +2 more sources
Optimizing extracellular matrix for endothelial differentiation using a design of experiments approach [PDF]
The extracellular matrix (ECM) plays a vital role in stem cell differentiation to endothelial cells in vivo and is also important for the specification of endothelial cells in vitro.
Mikayla L. Hall +2 more
doaj +2 more sources
Fibroblast mechanoperception instructs pulmonary developmental and pattern specification gene expression programs. [PDF]
Dysregulation of the cellular mechanisms that coordinate the interpretation and transduction of microenvironmental biophysical signals are a unifying feature of tissue remodeling pathologies such as fibrosis and cancer.
Andrew E Miller +6 more
doaj +2 more sources
8 × 8 element MIMO antenna for unmanned aerial vehicles, V2X and 5G applications [PDF]
In this study, a compact (30 × 30 × 0.508 mm3) 8-port MIMO antenna for unmanned aerial vehicles (UAV), vehicle-to-everything (V2X) and 5G applications is designed, developed, tested and discussed.
Brijesh Mishra +5 more
doaj +2 more sources
Concrete substrate moisture requirements for durable concrete repairs – a field study [PDF]
In concrete repair specifications, the required moisture condition of the substrate, which can play an important role for bond development, and, ultimately, on the long-term repair / overlay durability, is generally ill-defined and addressed without due ...
Bissonnette Benoit +5 more
doaj +1 more source
HAZELNUT SEED LIPASE: EXTRACTION, PURIFICATION, AND CHARACTERIZATION
Interest in lipases has markedly increased to their potential industrial applications. The most of lipases produced commercially are obtained from animal and microbial sources.
İsmail Kılıç, Ayten Sağıroğlu
doaj +6 more sources
Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis
Endothelial tip cell outgrowth of blood-vessel sprouts marks the initiation of angiogenesis which is critical in physiological and pathophysiological procedures.
Yaru Guo +10 more
doaj +1 more source
Substrate specificity of prostate-specific membrane antigen [PDF]
A series of putative dipeptide substrates of prostate-specific membrane antigen (PSMA) was prepared that explored alpha- and beta/gamma-linked acidic residues at the P1 position and various chromophores at the P2 position, while keeping the P1' residue constant as L-Glu.
Anderson, Marc O +6 more
openaire +3 more sources
Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells. [PDF]
Maintenance and differentiation of human pluripotent stem cells (hPSCs) usually requires culture on a substrate for cell adhesion. A commonly used substratum is Matrigel purified from Engelbreth-Holm-Swarm sarcoma cells, and consists of a complex mixture
Masato Nagaoka +4 more
doaj +1 more source
Coatings or films are applied to a substrate for several applications, such as waterproofing, corrosion resistance, adhesion performance, cosmetic effects, and optical coatings.
Adam Jones +6 more
doaj +1 more source

