Substrate Stiffness Modulates TGF-β1-Induced Lineage Specification in Multipotent Vascular Stem Cells [PDF]
CellsMultipotent vascular stem cells (MVSCs) are found in the vascular wall and surrounding tissues and possess the ability to differentiate into mesenchymal lineages.
Yujie Yan +5 more
doaj +4 more sources
Concrete substrate moisture requirements for durable concrete repairs – a field study [PDF]
MATEC Web of Conferences, 2022 In concrete repair specifications, the required moisture condition of the substrate, which can play an important role for bond development, and, ultimately, on the long-term repair / overlay durability, is generally ill-defined and addressed without due ...
Bissonnette Benoit +5 more
doaj +2 more sources
Assessment of the (010) β-Ga2O3 surface and substrate specification [PDF]
, 2020 Recent breakthroughs in bulk crystal growth of the thermodynamically stable beta phase of gallium oxide (β-Ga2O3) have led to the commercialization of large-area β-Ga2O3 substrates with subsequent epitaxy on (010) substrates producing high-quality films.
Michael A. Mastro +5 more
openalex +3 more sources
Local Presentation of Substrate Molecules Directs Axon Specification by Cultured Hippocampal Neurons [PDF]
Journal of Neuroscience, 1999 Axon specification is a crucial, early step in neuronal development, but little is known about how this event is controlledin vivo. To test the hypothesis that local presentation of growth-promoting molecules can direct axon specification, we cultured ...
Teresa Esch, Vance Lemmon, Gary Banker
openalex +2 more sources
Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions [PDF]
eLife, 2018 Metazoan development depends on tightly regulated gene expression programs that instruct progenitor cells to adopt specialized fates. Recent work found that posttranslational modifications, such as monoubiquitylation, can determine cell fate also ...
Achim Werner +4 more
doaj +3 more sources
Asynchronous mouse embryo polarization leads to heterogeneity in cell fate specification [PDF]
eLifeThe first lineage allocation in mouse and human embryos separates the inner cell mass (ICM) from the outer trophectoderm (TE). This symmetry-breaking event is executed through polarization of cells at the 8 cell stage and subsequent asymmetric divisions,
Adiyant Lamba +11 more
doaj +2 more sources
Gradients of substrate-bound laminin orient axonal specification of neurons [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2002 Stephan K. W. Dertinger +4 more
openalex +2 more sources
Bioengineering, 2017 Tissue engineering is a multi-disciplinary area of research bringing together the fields of engineering and life sciences with the aim of fabricating tissue constructs aiding in the regeneration of damaged tissues and organs. Scaffolds play a key role in
Sanjairaj Vijayavenkataraman +3 more
doaj +2 more sources
Optimizing extracellular matrix for endothelial differentiation using a design of experiments approach [PDF]
Scientific ReportsThe extracellular matrix (ECM) plays a vital role in stem cell differentiation to endothelial cells in vivo and is also important for the specification of endothelial cells in vitro.
Mikayla L. Hall +2 more
doaj +2 more sources
Fibroblast mechanoperception instructs pulmonary developmental and pattern specification gene expression programs. [PDF]
PLoS GeneticsDysregulation of the cellular mechanisms that coordinate the interpretation and transduction of microenvironmental biophysical signals are a unifying feature of tissue remodeling pathologies such as fibrosis and cancer.
Andrew E Miller +6 more
doaj +2 more sources