Results 181 to 190 of about 2,216,866 (310)

Substrate Specificity and Kinetic Mechanism of the NAD+-Dependent Deacylase from Mycobacterium tuberculosis, Rv1151c (Mt-Sirt). [PDF]

Biochemistry
Mellott DM, Zhu J, Fulcher H, Meek TD.
europepmc   +1 more source

Substrate specificity of amine oxidases [PDF]

Biochemical Journal, 1945
H, Blaschko, R, Duthie
openaire   +2 more sources

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Structure-activity relationship study shows versatility in substrate specificity for heterodisulfide reductase in methanogenic archaea. [PDF]

Protein Sci
Maleki MF, Jakobsen JB, Schuiten ED, Wagner T, Neves ALA, Bunch L.   +5 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

DeepAden: an explainable machine learning method for predicting the substrate specificity of nonribosomal peptide synthetases. [PDF]

Nucleic Acids Res
Huang J, Ge L, Wu Y, Tian Y, Wu J, Gao Q, Li P, Meng S, Zhang H, Qin Z.   +9 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Role of Ambler Position 104 in Defining Substrate Specificity in the KPC Family of β-Lactamases. [PDF]

ACS Infect Dis
Gao L, Marshall S, Bethel CR, Hujer AM, Taracila MA, Hujer KM, Haider S, Bonomo RA.   +7 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Structural factors governing alkane substrate specificity in the alkane monooxygenase (AlkB) family. [PDF]

C R Chim
Stańczak A, Bailey S, Heanue C, Rafalin N, Weinsaft E, Reinhardt C, Austin RN.   +6 more
europepmc   +1 more source