Structure-Function Analysis of an Understudied Type of LPMO with Unique Redox Properties and Substrate Specificity. [PDF]
Hall KR+12 more
europepmc +1 more source
Substrate specificity of amino acid transport in sheep erythrocytes [PDF]
James D. Young, J. C. Ellory
openalex +1 more source
Substrate (un)specificity of Arabidopsis NRT1/PTR FAMILY (NPF) proteins
C. Corratgé-Faillie, B. Lacombe
semanticscholar +1 more source
Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer+8 more
wiley +1 more source
Molecular determinants of substrate specificity in the efflux pump CraA from <i>Acinetobacter baumannii</i>. [PDF]
Foong WE, Xiang X, Pos KM, Tam H-K.
europepmc +1 more source
Substrate specificity and modifications of the active centre of elastase-like neutral proteinases from horse blood leucocytes [PDF]
Aleksander Koj+2 more
openalex +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Structural and functional insights into the substrate specificity of the pseudouridine monophosphate phosphatase HDHD1A. [PDF]
Seo S, Kim M, Rhee S.
europepmc +1 more source