Results 251 to 260 of about 10,438,012 (377)

Substrate specificity of amine oxidases [PDF]

Biochemical Journal, 1945
H. Blaschko, Ruth Duthie
openaire   +3 more sources

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity. [PDF]

Nat Commun
Wang M, Medarametla P, Kronenberger T, Deingruber T, Brear P, Figueroa W, Ho PM, Krueger T, Pearce JC, Poso A, Wakefield JG, Spring DR, Welch M.   +12 more
europepmc   +1 more source

Testicular steroid sulfatase: Substrate specificity and inhibition [PDF]

, 1969
Anita H. Payne, Merle Mason, Robert B. Jaffe   +2 more
openalex  

The substrate specificity of pepsin C [PDF]

Biochemical Journal, 1968
F Falla, A. P. Ryle, J Leclerc
openaire   +3 more sources

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Unraveling the molecular basis of substrate specificity and halogen activation in vanadium-dependent haloperoxidases. [PDF]

Nat Commun
Zeides P, Bellmann-Sickert K, Zhang R, Seel CJ, Most V, Schoeder CT, Groll M, Gulder T.   +7 more
europepmc   +1 more source

Specific Irreversible Inhibition of Enzymes Concomitant to the Oxidation of Carbanionic Enzyme · Substrate Intermediates by Hexacyanoferrate(III) [PDF]

, 1976
Philipp Christen, Marianne Cogoli‐Greuter, M. J. R. Healy, Ditmar G. E. Lubini   +3 more
openalex   +1 more source

Engineering the acyltransferase substrate specificity of assembly line polyketide synthases

Journal of the Royal Society Interface, 2013
Brian J. Dunn, C. Khosla
semanticscholar   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source