Results 31 to 40 of about 12,106 (297)

A New Synthesis of the Central Substructure of Botryococcenes

open access: yes, 2016
A New Synthesis of the Central Substructure of ...
Toshiro Ibuka (3007767)   +4 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Sensitivity-Based Substructure Error Propagation for Efficient Assembly Model Reduction

open access: yes, 2022
Due to ever-increasing complexity of structural dynamic systems in various fields of engineering, model reduction techniques using a substructuring approach, a.k.a. component mode synthesis techniques, still form an active field of research.
Verhees, M.L.J.   +7 more
core   +2 more sources

A substructure modal synthesis method with high computational efficiency

open access: yes, 2010
[[abstract]]A new substructure modal synthesis method is introduced. This method uses a set of trial frequencies and Gaussian elimination to find the expansion base vectors without solving the eigenvalue problem of each substructure.
WANG JH;CHEN HR
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A time-domain substructure synthesis for finite rotations of flexible mechanical systems

open access: yesMATEC Web of Conferences, 2018
This paper presents a floating IBS method for dynamic prediction of structures with finite rotations. The conventional IBS (impulse-based substructuring) method is efficient and accurate in structural transient impact analysis.
Chen Shulin, Liu Li, Chen Zhaoyue
doaj   +1 more source

From Target-Oriented to Motif-Oriented: A Case Study on Nannocystin Total Synthesis

open access: yesMolecules, 2020
Natural product total synthesis is in essence target-oriented in that a set of organic transformations are orchestrated into a workable process, leading ultimately to the target molecule with a predefined architecture.
Weicheng Zhang
doaj   +1 more source

Tabu Genetic Cat Swarm Algorithm Analysis of Optimization Arrangement on Mistuned Blades Based on CUDA

open access: yesShock and Vibration, 2021
Tabu genetic cat swarm optimization algorithm is proposed for optimization arrangement on mistuned blades. Furthermore, it is improved to be an innovative parallel algorithm based on Compute Unified Device Architecture (CUDA), whose performance is ...
Yi Cai   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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