Results 41 to 50 of about 12,061 (297)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Correction to “Design, Synthesis, and Antibacterial Evaluation of Oxazolidinones with Fused Heterocyclic C‑Ring Substructure”

, 2018
Correction to “Design, Synthesis, and Antibacterial Evaluation of Oxazolidinones with Fused Heterocyclic C‑Ring ...
Nidhi Jain (1507936), Mahesh S. Deshmukh (2554873)   +1 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Crystal structure of 4-nitrophenyl 6-O-ethyl-β-d-galactopyranoside monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2017
The synthesis and crystal structure of the title compound, C14H19NO8·H2O, prepared in three steps from 6-O-ethyl-1,2;3,4-di-O-isopropylidene-α-d-galactopyranose using protecting-group strategies employed in carbohydrate chemistry, is reported.
Bruno Leonardo Silva, Ricardo José Alves, Nivaldo Lúcio Speziali   +2 more
doaj   +1 more source

Reduction of Coupling Interface Degrees of Freedom in Mixed-Interface Component Mode Synthesis

Applied Sciences, 2020
A new coupling interface degrees of freedom (DOFs) reduction technique for the mixed-interface component mode synthesis (MCMS) method is proposed, which referred to as the MCMS-rid method.
Yu Tang, Hui Qin
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Optimized Identification of Bolt Joint’s Tangential Dynamic Stiffness Based on the Substructure Synthesis Method

工程科学与技术, 2015
:For the ill-posed problem caused by noise in the identification of bolt joint’s equivalent dynamic parameters based on frequency response functions (FRFs), an optimized identification method was put forward to obtain the accurate parameters.
TAN FENG, Yin Guofu, DONG GUANHUA, WANG LIANG, TANG WEIXIN   +4 more
doaj  

Dynamic Modeling and Experimental Verification of an RPR Type Compliant Parallel Mechanism with Low Orders

Chinese Journal of Mechanical Engineering
Efficiency of calculating a dynamic response is an important point of the compliant mechanism for posture adjustment. Dynamic modeling with low orders of a 2R1T compliant parallel mechanism is studied in the paper.
Shuang Zhang, Jingfang Liu, Huafeng Ding, Yanbin Zhang   +3 more
doaj   +1 more source

Design, synthesis and biological evaluation of thiazole and imidazo[1,2-a]pyridine derivatives containing a hydrazone substructure as potential agrochemicals

Advanced Agrochem, 2023
Agricultural chemicals with multifunctional applications in crop protection have attracted increasing attention. Herein, two new series of thiazole and imidazo[1,2-a]pyridine derivatives containing a hydrazone substructure were designed and synthesized ...
Xiaofang Yao, Rongrong Zhang, Bo Lv, Wei-Wei Wang, Zhigang Liu, Zhaonong Hu, Ding Li   +6 more
doaj   +1 more source