Results 11 to 20 of about 17,568 (222)

Subacute alpha frequency (10Hz) subthalamic stimulation for emotional processing in Parkinson's disease

open access: yesBrain Stimulation, 2023
Background: Psychiatric comorbidities are common in Parkinson's disease (PD) and may change with high-frequency stimulation targeting the subthalamic nucleus.
Linbin Wang   +5 more
doaj   +1 more source

Topography and distribution of adenosine A2A and dopamine D2 receptors in the human Subthalamic Nucleus

open access: yesFrontiers in Neuroscience, 2022
The human Subthalamic Nucleus (STh) is a diencephalic lens-shaped structure located ventrally to the thalamus and functionally implicated in the basal ganglia circuits.
Aron Emmi   +15 more
doaj   +1 more source

The subthalamic nucleus becomes a generator of bursts in the dopamine-depleted state. Its high frequency stimulation dramatically weakens transmission to the globus pallidus

open access: yesFrontiers in Systems Neuroscience, 2011
Excessive burst firing in the dopamine-depleted basal ganglia correlates with severe motor symptoms of Parkinson’s disease that are attenuated by high frequency electrical stimulation of the subthalamic nucleus.
Rachida eAmmari   +4 more
doaj   +1 more source

Subthalamic Nucleus Stimulation [PDF]

open access: yesArchives of Neurology, 2006
Deep brain stimulation (DBS) is currently the most effective surgical treatment for advanced Parkinson disease (PD). Even when the electrode is well positioned in the target, the optimization of clinical results depends on careful programming of electrical parameters and changes in antiparkinsonian drug dosages.To determine whether stable outcomes from
Elena, Moro   +4 more
openaire   +2 more sources

Targeting the Subthalamic Nucleus

open access: yesStereotactic and Functional Neurosurgery, 2001
The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN.
Aziz, T   +9 more
openaire   +3 more sources

Subthalamic nucleus detects unnatural android movement [PDF]

open access: yesScientific Reports, 2017
AbstractAn android, i.e., a realistic humanoid robot with human-like capabilities, may induce an uncanny feeling in human observers. The uncanny feeling about an android has two main causes: its appearance and movement. The uncanny feeling about an android increases when its appearance is almost human-like but its movement is not fully natural or ...
Takashi Ikeda   +7 more
openaire   +2 more sources

Subthalamic nucleus stimulation and levodopa modulate cardiovascular autonomic function in Parkinson’s disease

open access: yesScientific Reports, 2017
We aimed to explore the effects of bilateral subthalamic nucleus stimulation and levodopa on cardiovascular autonomic function in Parkinson’s disease.
Kai Li   +6 more
doaj   +1 more source

Development of a novel gripping test for the evaluation of the finger fine motor ability in MPTP-treated monkeys [PDF]

open access: yesJournal of Integrative Neuroscience, 2020
Assessing the finger fine motor ability is extremely important. However, conventional behavioral tests in monkeys are complicated and costly. We attempted to develop a new task to assess the precise finger grip in Parkinson's disease monkeys based on the
Susumu Kobayashi, Tetsuya Asakawa, Takao Nozaki, Kenji Sugiyama, Tetsuro Sameshima, Kazuhiko Kurozumi
doaj   +1 more source

The subcortical cocktail problem; mixed signals from the subthalamic nucleus and substantia nigra.

open access: yesPLoS ONE, 2015
The subthalamic nucleus and the directly adjacent substantia nigra are small and important structures in the basal ganglia. Functional magnetic resonance imaging studies have shown that the subthalamic nucleus and substantia nigra are selectively ...
Gilles de Hollander   +2 more
doaj   +1 more source

Dynamic modulation of subthalamic nucleus activity facilitates adaptive behavior.

open access: yesPLoS Biology, 2023
Adapting actions to changing goals and environments is central to intelligent behavior. There is evidence that the basal ganglia play a crucial role in reinforcing or adapting actions depending on their outcome.
Damian M Herz   +10 more
doaj   +1 more source

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