Results 11 to 20 of about 488,438 (323)
Annals of Neurology, 2022 This study was undertaken to compare the rate of change in cognition between glucocerebrosidase (GBA) mutation carriers and noncarriers with and without subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson disease.
Gian D Pal +30 more
semanticscholar +1 more source
Principles of gait encoding in the subthalamic nucleus of people with Parkinson’s disease
Science Translational Medicine, 2022 Disruption of subthalamic nucleus dynamics in Parkinson’s disease leads to impairments during walking. Here, we aimed to uncover the principles through which the subthalamic nucleus encodes functional and dysfunctional walking in people with Parkinson’s ...
Yohann Thenaisie +16 more
semanticscholar +1 more source
Neural Regeneration Research, 2023 There are many documented sex differences in the clinical course, symptom expression profile, and treatment response of Parkinson’s disease, creating additional challenges for patient management.
Tian-Shuo Yuan +7 more
doaj +1 more source
Targeting the Subthalamic Nucleus [PDF]
Stereotactic and Functional Neurosurgery, 2001 The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN.
Aziz, T +9 more
openaire +3 more sources
Mathematical model of subthalamic nucleus neuron: characteristic activity patterns and bifurcation analysis [PDF]
Chaos 31, 113121 (2021), 2021 The subthalamic nucleus (STN) has an important role in the pathophysiology of the basal ganglia in Parkinson's disease. The ability of STN cells to generate bursting rhythms under either transient or sustained hyperpolarization may underlie the excessively synchronous beta rhythms observed in Parkinson's disease.
arxiv +1 more source
Neural Regeneration Research, 2021 Deep brain stimulation of the bilateral subthalamic nucleus (STN) is a therapeutic option for patients with Parkinson’s disease (PD) in whom medical therapies have been ineffective.
Guo-Xiong Cheng +6 more
doaj +1 more source
Journal of Contemporary Medicine, 2023 Background: Although the subtahalamic nucleus degeneration has been accused of Parkinson’s disease, the obscure roles of subtalamic nucleus degeneration induced by subarachnoid hemorrhages has not been adequately studied.
Mehmet Hakan Şahin, Mete Zeynal
doaj +1 more source
Deep brain stimulation electrode position impact on parkinsonian non-motor symptoms
Biomedical Papers, 2022 Background. In this study we evaluated the impact of location of deep brain stimulation electrode active contact in different parts of the subthalamic nucleus on improvement of non-motor symptoms in patients with Parkinson's disease. Methods.
Jan Bardon +15 more
doaj +1 more source
Subthalamic Nucleus Deep Brain Stimulation Modulates 2 Distinct Neurocircuits
Annals of Neurology, 2020 Current understanding of the neuromodulatory effects of deep brain stimulation (DBS) on large‐scale brain networks remains elusive, largely due to the lack of techniques that can reveal DBS‐induced activity at the whole‐brain level.
Lunhao Shen +13 more
semanticscholar +1 more source
Imaging of the human subthalamic nucleus
, 2021 The human subthalamic nucleus (STN) is a small lens shaped iron rich nucleus, which has gained substantial interest as a target for deep brain stimulation surgery for a variety of movement disorders. The internal anatomy of the human STN has not been fully elucidated, and an intensive debate, discussing the level of overlap between putative limbic ...
Alkemade, Anneke, Forstmann, Birte U.
openaire +3 more sources