Results 31 to 40 of about 335,108 (249)

Brain tissue properties differentiate between motor and limbic basal ganglia circuits [PDF]

, 2014
Despite advances in understanding basic organizational principles of the human basal ganglia, accurate in vivo assessment of their anatomical properties is essential to improve early diagnosis in disorders with corticosubcortical pathology and optimize ...
Haynes, J., Weiskopf, N, Ettore A. Accolla, Dukart, J., Kherif, Ferath, Weiskopf, N. ; https://orcid.org/, Kuehn, Andrea A., Helms, Gunther, Gunther Helms, Weiskopf, Nikolaus, Rumana Chowdhury, John‐Dylan Haynes, Chowdhury, R., Dukart, Jürgen, Draganski, Bogdan, Stefan Hetzer, Hetzer, S, Kühn, Andrea A., Draganski, B. ; https://orcid.org/, Accolla, E., Haynes, John-Dylan, Ferath Kherif, Juergen Dukart, Kühn, AA, Accolla, Ettore A., Chowdhury, R, Andrea A. Kühn, Dukart, Juergen, Chowdhury, Rumana, Hetzer, Stefan, Antoine Lutti, Hetzer, S., Lutti, Antoine, Accolla, EA, Draganski, B, Helms, Gunther,, Nikolaus Weiskopf, Kühn, A., Bogdan Draganski, Kherif, F., Kherif, F, Helms, G., Helms, G, Lutti, A, Lutti, A., Lund University., Dukart, J, Haynes, J-D   +47 more
core   +1 more source

Depression history modulates effects of subthalamic nucleus topography on neuropsychological outcomes of deep brain stimulation for Parkinson’s disease

Translational Psychiatry, 2022
Patients with psychiatric symptoms, such as depression, anxiety, and visual hallucinations, may be at increased risk for adverse effects following deep brain stimulation of the subthalamic nucleus for Parkinson’s disease, but there have been relatively ...
Ian H. Kratter, Ahmed Jorge, Michael T. Feyder, Ashley C. Whiteman, Yue-fang Chang, Luke C. Henry, Jordan F. Karp, R. Mark Richardson   +7 more
doaj   +1 more source

Development of a novel gripping test for the evaluation of the finger fine motor ability in MPTP-treated monkeys [PDF]

Journal of Integrative Neuroscience, 2020
Assessing the finger fine motor ability is extremely important. However, conventional behavioral tests in monkeys are complicated and costly. We attempted to develop a new task to assess the precise finger grip in Parkinson's disease monkeys based on the
Susumu Kobayashi, Tetsuya Asakawa, Takao Nozaki, Kenji Sugiyama, Tetsuro Sameshima, Kazuhiko Kurozumi
doaj   +1 more source

Dorsal subthalamic nucleus targeting in deep brain stimulation:microelectrode recording versus 7-Tesla connectivity [PDF]

, 2023
Connectivity-derived 7-Tesla MRI segmentation and intraoperative microelectrode recording can both assist subthalamic nucleus targeting for deep brain stimulation in Parkinson's disease. It remains unclear whether deep brain stimulation electrodes placed
Potters, Wouter V., Kremer, Naomi I, Dilai, José, C. van Dijk, J. Marc, Rijks, Niels, de Bie, Rob M A, Mathiopoulou, Varvara, Kremer, Naomi I., Drost, Gea; id_orcid, Janssen, Marcus L.F.; id_orcid, van Laar, Teus, van den Munckhof, Pepijn, Potters, Wouter V, Bot, Maarten, Roberts, Mark J, van Dijk, J Marc C, Janssen, Marcus L F, Beudel, Martijn, Kremer, Naomi I; id_orcid, Schuurman, P Richard, van Dijk, J Marc C; id_orcid, Drost, Gea, Roberts, Mark J.; id_orcid, Schuurman, P. Richard, de Bie, Rob M.A.   +24 more
core   +1 more source

Modelling the effects of deep brain stimulation in the pedunculopontine tegmental nucleus in Parkinson’s disease [PDF]

, 2014
Based on the belief that it is a locomotor control structure, the pedunculopontine tegmental nucleus (PPTg) has been considered a potential target for deep brain stimulation (DBS) for Parkinson’s disease (PD) patients with symptoms refractory to ...
Gut, Nadine Katrin
core   +2 more sources

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats

Neurobiology of Disease, 2012
Huntington's disease (HD) is characterized by neuronal loss in the striatum, ultimately leading to an ‘imbalance’ in the electrical activity of the basal ganglia-thalamocortical circuits.
Rinske Vlamings, Abdelhamid Benazzouz, Jonathan Chetrit, Marcus L.F. Janssen, Ramazan Kozan, Veerle Visser-Vandewalle, Harry W.M. Steinbusch, Stephan von Hörsten, Yasin Temel   +8 more
doaj   +1 more source

Functional atlases for analysis of motor and neuropsychological outcomes after medial globus pallidus and subthalamic stimulation.

PLoS ONE, 2018
Anatomical atlases have been developed to improve the targeting of basal ganglia in deep brain stimulation. However, the sole anatomy cannot predict the functional outcome of this surgery.
Claire Haegelen, Clément Baumgarten, Jean-François Houvenaghel, Yulong Zhao, Julie Péron, Sophie Drapier, Pierre Jannin, Xavier Morandi   +7 more
doaj   +1 more source

Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease [PDF]

, 2015
Background Patients with advanced Parkinson's disease (PD) often present with axial symptoms, including postural- and gait difficulties that respond poorly to dopaminergic agents.
Pienaar, Ilse, De Paola, V, Gretenkord, Sabine, David Dexter (3572210), Sabine Gretenkord, Withers, Dominic, Ilse Pienaar (4504357), Dominic Withers (3572216), Gartside, Sarah, De Paola, Vincenzo, Puneet Sharma, Ilse S. Pienaar, Puneet Sharma (3572222), Sharma, Puneet, Dominic Withers, Sabine Gretenkord (3572213), David T. Dexter, Vincenzo De Paola, Joanna L. Elson, Ilse Pienaar (3572219), Joanna L Elson (16036517), Sarah Gartside (3572225), Dexter, David, Elson, Joanna, Sarah E. Gartside, Joanna Elson (271089), Vincenzo De Paola (275215), Sarah E Gartside (16264538), David T Dexter (9237410)   +28 more
core   +1 more source

In Parkinson’s disease dopaminergic medication and deep brain stimulation of the subthalamic nucleus increase motor, but not reflection and cognitive impulsivity

Frontiers in Neuroscience
BackgroundParkinson’s disease is associated with increased impulsivity, which can be divided into several domains: motor (consisting of proactive and reactive subdomains), reflection, and cognitive impulsivity.
Martijn Hendriks, Martijn Hendriks, Saman Vinke, Rok Berlot, Rok Berlot, Mitja Benedičič, Marjan Jahansahi, Maja Trošt, Maja Trošt, Dejan Georgiev, Dejan Georgiev   +10 more
doaj   +1 more source

Sweetspot Mapping in Deep Brain Stimulation: Strengths and Limitations of Current Approaches

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Open questions remain regarding the optimal target, or sweetspot, for deep brain stimulation (DBS) in, for example, Parkinson's disease. Previous studies introduced different methods of mapping DBS effects to determine sweetspots. While having a direct impact on surgical targeting and postoperative programming in DBS, these methods ...
Till A. Dembek, Juan Carlos Baldermann, Jan‐Niklas Petry‐Schmelzer, Hannah Jergas, Harald Treuer, Veerle Visser‐Vandewalle, Haidar S. Dafsari, Michael T. Barbe   +7 more
wiley   +1 more source