Results 41 to 50 of about 17,967 (218)
Diffusion MRI and α‐Synuclein Seed Amplification Status in Parkinson's Disease
Annals of Neurology, EarlyView.Objective Positive α‐synuclein seed amplification assay (SAA) is a biomarker found in most people with Parkinson's disease (PD). We explored if free‐water (FW) imaging detects microstructural differences in the brains of patients with early PD with SAA+ or SAA– status.
Shannon Y. Chiu +145 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Obsessive–compulsive disorder (OCD) is a psychiatric disorder with alterations of cortico‐striato‐thalamo‐cortical loops and impaired performance monitoring. Electrophysiological markers such as conflict‐related medial frontal theta (MFT) and error‐related negativity (ERN) may be altered by clinically effective deep brain ...
Elena Sildatke +9 more
wiley +1 more source
NeuroImage: Clinical, 2018 Deep brain stimulation of the subthalamic nucleus for Parkinson's disease is an established advanced therapy that addresses motor symptoms and improves quality of life.
Philip E. Mosley +5 more
doaj +1 more source
Subdivisions and Anatomical Boundaries of the Subthalamic Nucleus [PDF]
The Journal of Neuroscience, 2013 The subthalamic nucleus (STN) lies deep within the brain and plays a central role in both the direct and indirect pathway of the basal ganglia ([Temel et al., 2005][1]). The nucleus itself does not degenerate in patients with Parkinson's disease, but it is an important target for deep ...
openaire +4 more sources
Annals of Neurology, EarlyView.Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže +17 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objective To evaluate the effects of bilateral caudal zona incerta (cZi) deep brain stimulation (DBS) for Parkinson's disease (PD) one year after surgery and to create anatomical improvement maps based on patient‐specific simulation of the electric field.
Rasmus Stenmark Persson +6 more
wiley +1 more source
Neurotransmitter and receptor systems in the subthalamic nucleus
Brain Structure and Function, 2023 AbstractThe Subthalamic Nucleus (STh) is a lens-shaped subcortical structure located ventrally to the thalamus, that despite being embryologically derived from the diencephalon, is functionally implicated in the basal ganglia circuits. Because of this strict structural and functional relationship with the circuits of the basal ganglia, the STh is a ...
Emmi, Aron +7 more
openaire +4 more sources
Moving beyond neurophobia to cultivate the neuroquisitive learner
Anatomical Sciences Education, EarlyView.Abstract “Neurophobia,” a pervasive fear of the neurological sciences, poses a significant barrier in medical education, affecting learners and physicians worldwide. Its consequences are far‐reaching, contributing to a limited neurology workforce and diminished confidence among non‐specialists in managing neurological conditions.
Joanna R. Appel +1 more
wiley +1 more source
Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano +10 more
wiley +1 more source
Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice
Nature Communications, 2021 Innate and learned fear can induce rapid changes in body temperature of mammals. The authors identify the posterior subthalamic nucleus as a major thermoregulatory hub that connects the external lateral parabrachial subnucleus to the nucleus of the ...
Can Liu +9 more
doaj +1 more source