Results 21 to 30 of about 17,967 (218)
Development of a novel gripping test for the evaluation of the finger fine motor ability in MPTP-treated monkeys [PDF]
Journal of Integrative Neuroscience, 2020 Assessing the finger fine motor ability is extremely important. However, conventional behavioral tests in monkeys are complicated and costly. We attempted to develop a new task to assess the precise finger grip in Parkinson's disease monkeys based on the
Susumu Kobayashi, Tetsuya Asakawa, Takao Nozaki, Kenji Sugiyama, Tetsuro Sameshima, Kazuhiko Kurozumi
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Translational Psychiatry, 2022 Patients with psychiatric symptoms, such as depression, anxiety, and visual hallucinations, may be at increased risk for adverse effects following deep brain stimulation of the subthalamic nucleus for Parkinson’s disease, but there have been relatively ...
Ian H. Kratter +7 more
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Neurobiology of Disease, 2012 Huntington's disease (HD) is characterized by neuronal loss in the striatum, ultimately leading to an ‘imbalance’ in the electrical activity of the basal ganglia-thalamocortical circuits.
Rinske Vlamings +8 more
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Subthalamic Nucleus Stimulation [PDF]
Archives of Neurology, 2006 Deep brain stimulation (DBS) is currently the most effective surgical treatment for advanced Parkinson disease (PD). Even when the electrode is well positioned in the target, the optimization of clinical results depends on careful programming of electrical parameters and changes in antiparkinsonian drug dosages.To determine whether stable outcomes from
Elena, Moro +4 more
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Analysis of patient-specific stimulation with segmented leads in the subthalamic nucleus.
PLoS ONE, 2019 ObjectiveSegmented deep brain stimulation leads in the subthalamic nucleus have shown to increase therapeutic window using directional stimulation. However, it is not fully understood how these segmented leads with reduced electrode size modify the ...
T A Khoa Nguyen +6 more
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PLoS ONE, 2018 Anatomical atlases have been developed to improve the targeting of basal ganglia in deep brain stimulation. However, the sole anatomy cannot predict the functional outcome of this surgery.
Claire Haegelen +7 more
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A role for the subthalamic nucleus in aversive learning
Cell Reports, 2023 The subthalamic nucleus (STN) is critical for behavioral control; its dysregulation consequently correlated with neurological and neuropsychiatric disorders, including Parkinson's disease. Deep brain stimulation (DBS) targeting the STN successfully alleviates parkinsonian motor symptoms. However, low mood and depression are affective side effects.
Serra, Gian Pietro +9 more
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Frontiers in NeuroscienceBackgroundParkinson’s disease is associated with increased impulsivity, which can be divided into several domains: motor (consisting of proactive and reactive subdomains), reflection, and cognitive impulsivity.
Martijn Hendriks +10 more
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Nomogram for Predicting Depression Improvement after Deep Brain Stimulation for Parkinson’s Disease
Brain Sciences, 2022 Background: Parkinson’s disease is a common neurodegenerative disease, with depression being a common non-motor symptom. Bilateral subthalamic nucleus deep brain stimulation is an effective method for the treatment of Parkinson’s disease.
Bowen Chang +6 more
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Subthalamic Nucleus: Neuroanatomical Review
Brazilian Neurosurgery, 2017 Discovered in 1865 by Jules Bernard Luys, the subthalamic nucleus is a set of small nuclei located in the diencephalon, inferior to the thalamus and superior to the substantia nigra, that can be visualized in a posterior coronal section.
Marcelo José Silva de Magalhães +9 more
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