Results 21 to 30 of about 38,228 (259)

Decisional impulsivity and the associative-limbic subthalamic nucleus in obsessive-compulsive disorder: stimulation and connectivity. [PDF]

, 2016
Why do we make hasty decisions for short-term gain? Rapid decision-making with limited accumulation of evidence and delay discounting are forms of decisional impulsivity.
Bougerol, Thierry, Chabardes, Stephan, David, Olivier, Droux, Fabien, Krack, Paul, Morris, Laurel, Polosan, Mircea, Voon, Valerie   +7 more
core   +2 more sources

Optogenetics and deep brain stimulation neurotechnologies [PDF]

, 2015
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt, A Berndt, A Priori, AA Kuhn, AA Kuhn, AS Chuong, B Sauer, B Wingeier, BY Chow, BY Chow, C Bamann, D Luo, D Oesterhelt, D Oesterhelt, D Williams, ES Boyden, EY Uc, F Zhang, F Zhang, G Foffani, G Miesenbock, G Nagel, J Cavanaugh, J Mobley, J Volkmann, J Wells, J Wietek, JG Bernstein, JG Bernstein, JG Bernstein, JL Spudich, JL Spudich, JO Dostrovsky, JZ Tsien, L Bekar, L Madisen, LA Gunaydin, M Weinberger, M Weinberger, MC Rodriguez-Oroz, MJ Lehmkuhle, ML Welter, MM Doroudchi, O Yizhar, P Brown, P Silberstein, R Levy, R Levy, R Levy, R Waehler, S Zhao, TW Chen, VC Anderson, X Han, X Han, X Han, X Han, X Han, X Liu   +58 more
core   +2 more sources

Subthalamic nucleus stimulation and levodopa modulate cardiovascular autonomic function in Parkinson’s disease

Scientific Reports, 2017
We aimed to explore the effects of bilateral subthalamic nucleus stimulation and levodopa on cardiovascular autonomic function in Parkinson’s disease.
Kai Li, Rocco Haase, Heinz Rüdiger, Manja Reimann, Heinz Reichmann, Martin Wolz, Tjalf Ziemssen   +6 more
doaj   +1 more source

Imaging of the human subthalamic nucleus

, 2021
The human subthalamic nucleus (STN) is a small lens shaped iron rich nucleus, which has gained substantial interest as a target for deep brain stimulation surgery for a variety of movement disorders. The internal anatomy of the human STN has not been fully elucidated, and an intensive debate, discussing the level of overlap between putative limbic ...
Alkemade, A., Forstmann, B.U.
openaire   +4 more sources

The subcortical cocktail problem; mixed signals from the subthalamic nucleus and substantia nigra.

PLoS ONE, 2015
The subthalamic nucleus and the directly adjacent substantia nigra are small and important structures in the basal ganglia. Functional magnetic resonance imaging studies have shown that the subthalamic nucleus and substantia nigra are selectively ...
Gilles de Hollander, Max C Keuken, Birte U Forstmann   +2 more
doaj   +1 more source

Dynamic modulation of subthalamic nucleus activity facilitates adaptive behavior.

PLoS Biology, 2023
Adapting actions to changing goals and environments is central to intelligent behavior. There is evidence that the basal ganglia play a crucial role in reinforcing or adapting actions depending on their outcome.
Damian M Herz, Manuel Bange, Gabriel Gonzalez-Escamilla, Miriam Auer, Muthuraman Muthuraman, Martin Glaser, Rafal Bogacz, Alek Pogosyan, Huiling Tan, Sergiu Groppa, Peter Brown   +10 more
doaj   +1 more source

Development of a novel gripping test for the evaluation of the finger fine motor ability in MPTP-treated monkeys [PDF]

Journal of Integrative Neuroscience, 2020
Assessing the finger fine motor ability is extremely important. However, conventional behavioral tests in monkeys are complicated and costly. We attempted to develop a new task to assess the precise finger grip in Parkinson's disease monkeys based on the
Susumu Kobayashi, Tetsuya Asakawa, Takao Nozaki, Kenji Sugiyama, Tetsuro Sameshima, Kazuhiko Kurozumi
doaj   +1 more source

Depression history modulates effects of subthalamic nucleus topography on neuropsychological outcomes of deep brain stimulation for Parkinson’s disease

Translational Psychiatry, 2022
Patients with psychiatric symptoms, such as depression, anxiety, and visual hallucinations, may be at increased risk for adverse effects following deep brain stimulation of the subthalamic nucleus for Parkinson’s disease, but there have been relatively ...
Ian H. Kratter, Ahmed Jorge, Michael T. Feyder, Ashley C. Whiteman, Yue-fang Chang, Luke C. Henry, Jordan F. Karp, R. Mark Richardson   +7 more
doaj   +1 more source

Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease [PDF]

, 2003
Background: Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease have been well documented, the long-term outcomes of the procedure are unknown. Methods: We conducted a five-
Krack, P., Batir, A., Van Blercom, N., Chabardes, S., Fraix, V., Ardouin, C., Koudsie, A., Limousin, P.D., Benazzouz, A., LeBas, J.F., Benabid, A.-L., Pollak, P.   +11 more
core   +4 more sources

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats

Neurobiology of Disease, 2012
Huntington's disease (HD) is characterized by neuronal loss in the striatum, ultimately leading to an ‘imbalance’ in the electrical activity of the basal ganglia-thalamocortical circuits.
Rinske Vlamings, Abdelhamid Benazzouz, Jonathan Chetrit, Marcus L.F. Janssen, Ramazan Kozan, Veerle Visser-Vandewalle, Harry W.M. Steinbusch, Stephan von Hörsten, Yasin Temel   +8 more
doaj   +1 more source