Results 11 to 20 of about 17,967 (218)

Architecture of the subthalamic nucleus

open access: yesCommunications Biology
The subthalamic nucleus (STN) is a major neuromodulation target for the alleviation of neurological and neuropsychiatric symptoms using deep brain stimulation (DBS). STN-DBS is today applied as treatment in Parkinson´s disease, dystonia, essential tremor,
Asheeta A. Prasad   +1 more
doaj   +4 more sources

Unraveling the enigmatic role of the subthalamic nucleus

open access: yeseLife
Subpopulations of neurons in the subthalamic nucleus have distinct activity patterns that relate to the three hypotheses of the Drift Diffusion Model.
Qianli Yang
doaj   +3 more sources

Are there three Subdivisions in the primate Subthalamic Nucleus? [PDF]

open access: yesFrontiers in Neuroanatomy, 2012
The prevailing academic opinion holds that the subthalamic nucleus (STN) consists of three parts, each anatomically distinct and selectively associated with cognitive, emotional, or motor functioning.
Max C Keuken   +7 more
doaj   +8 more sources

The subthalamic nucleus, oscillations, and conflict [PDF]

open access: yesMovement Disorders, 2015
AbstractThe subthalamic nucleus (STN), which is currently the most common target for deep brain stimulation (DBS) for Parkinson's disease (PD), has received increased attention over the past few years for the roles it may play in functions beyond simple motor control.
Baltazar, Zavala   +2 more
openaire   +2 more sources

The role of the subthalamic nucleus in cognition [PDF]

open access: yesReviews in the Neurosciences, 2013
Because the complex functions of the basal ganglia have been increasingly studied over the past several decades, the understanding of the role of the subthalamic nucleus (STN) in motor and cognitive functions has evolved. The traditional role in motor function ascribed to the STN, based on its involvement in the cortico-striato-thalamo-cortical motor ...
David B, Weintraub, Kareem A, Zaghloul
openaire   +2 more sources

Targeting the Subthalamic Nucleus

open access: yesStereotactic and Functional Neurosurgery, 2001
The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN.
Aziz, T   +9 more
openaire   +3 more sources

Subthalamic nucleus stimulation and levodopa modulate cardiovascular autonomic function in Parkinson’s disease

open access: yesScientific Reports, 2017
We aimed to explore the effects of bilateral subthalamic nucleus stimulation and levodopa on cardiovascular autonomic function in Parkinson’s disease.
Kai Li   +6 more
doaj   +1 more source

Imaging of the human subthalamic nucleus

open access: yes, 2021
The human subthalamic nucleus (STN) is a small lens shaped iron rich nucleus, which has gained substantial interest as a target for deep brain stimulation surgery for a variety of movement disorders. The internal anatomy of the human STN has not been fully elucidated, and an intensive debate, discussing the level of overlap between putative limbic ...
Alkemade, A., Forstmann, B.U.
openaire   +4 more sources

The subcortical cocktail problem; mixed signals from the subthalamic nucleus and substantia nigra.

open access: yesPLoS ONE, 2015
The subthalamic nucleus and the directly adjacent substantia nigra are small and important structures in the basal ganglia. Functional magnetic resonance imaging studies have shown that the subthalamic nucleus and substantia nigra are selectively ...
Gilles de Hollander   +2 more
doaj   +1 more source

Dynamic modulation of subthalamic nucleus activity facilitates adaptive behavior.

open access: yesPLoS Biology, 2023
Adapting actions to changing goals and environments is central to intelligent behavior. There is evidence that the basal ganglia play a crucial role in reinforcing or adapting actions depending on their outcome.
Damian M Herz   +10 more
doaj   +1 more source

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