Results 11 to 20 of about 38,228 (259)
Neurobiology of Disease, 2023 Background: Recent animal model studies have suggested that the parafascicular nucleus has the potential to be an effective deep brain stimulation target for Parkinson's disease.
Lili Chen +8 more
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Brain tissue properties differentiate between motor and limbic basal ganglia circuits [PDF]
, 2014 Despite advances in understanding basic organizational principles of the human basal ganglia, accurate in vivo assessment of their anatomical properties is essential to improve early diagnosis in disorders with corticosubcortical pathology and optimize ...
Accolla, EA +10 more
core +6 more sources
PLoS ONE, 2020 BackgroundIn addition to the typical motor symptoms, a majority of patients suffering from Parkinson's disease experience language impairments. Deep Brain Stimulation of the subthalamic nucleus robustly reduces motor dysfunction, but its impact on ...
Felicitas Ehlen +3 more
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Brain Stimulation, 2023 Background: Psychiatric comorbidities are common in Parkinson's disease (PD) and may change with high-frequency stimulation targeting the subthalamic nucleus.
Linbin Wang +5 more
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The subthalamic nucleus, oscillations, and conflict [PDF]
Movement Disorders, 2015 AbstractThe subthalamic nucleus (STN), which is currently the most common target for deep brain stimulation (DBS) for Parkinson's disease (PD), has received increased attention over the past few years for the roles it may play in functions beyond simple motor control.
Baltazar, Zavala +2 more
openaire +2 more sources
Potential mechanisms for imperfect synchronization in parkinsonian basal ganglia [PDF]
, 2012 Neural activity in the brain of parkinsonian patients is characterized by the intermittently synchronized oscillatory dynamics. This imperfect synchronization, observed in the beta frequency band, is believed to be related to the hypokinetic motor ...
Park, Choongseok, Rubchinsky, Leonid
core +6 more sources
Frontiers in Neuroscience, 2022 The human Subthalamic Nucleus (STh) is a diencephalic lens-shaped structure located ventrally to the thalamus and functionally implicated in the basal ganglia circuits.
Aron Emmi +15 more
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Targeting the Subthalamic Nucleus
Stereotactic and Functional Neurosurgery, 2001 The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN.
Aziz, T +9 more
openaire +3 more sources
Frontiers in Systems Neuroscience, 2011 Excessive burst firing in the dopamine-depleted basal ganglia correlates with severe motor symptoms of Parkinson’s disease that are attenuated by high frequency electrical stimulation of the subthalamic nucleus.
Rachida eAmmari +4 more
doaj +1 more source
The role of the subthalamic nucleus in cognition [PDF]
Reviews in the Neurosciences, 2013 Because the complex functions of the basal ganglia have been increasingly studied over the past several decades, the understanding of the role of the subthalamic nucleus (STN) in motor and cognitive functions has evolved. The traditional role in motor function ascribed to the STN, based on its involvement in the cortico-striato-thalamo-cortical motor ...
David B, Weintraub, Kareem A, Zaghloul
openaire +2 more sources