Results 21 to 30 of about 17,568 (222)
Translational Psychiatry, 2022 Patients with psychiatric symptoms, such as depression, anxiety, and visual hallucinations, may be at increased risk for adverse effects following deep brain stimulation of the subthalamic nucleus for Parkinson’s disease, but there have been relatively ...
Ian H. Kratter +7 more
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The subthalamic nucleus, oscillations, and conflict [PDF]
Movement Disorders, 2015 AbstractThe subthalamic nucleus (STN), which is currently the most common target for deep brain stimulation (DBS) for Parkinson's disease (PD), has received increased attention over the past few years for the roles it may play in functions beyond simple motor control.
Baltazar, Zavala +2 more
openaire +2 more sources
Neurobiology of Disease, 2012 Huntington's disease (HD) is characterized by neuronal loss in the striatum, ultimately leading to an ‘imbalance’ in the electrical activity of the basal ganglia-thalamocortical circuits.
Rinske Vlamings +8 more
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Analysis of patient-specific stimulation with segmented leads in the subthalamic nucleus.
PLoS ONE, 2019 ObjectiveSegmented deep brain stimulation leads in the subthalamic nucleus have shown to increase therapeutic window using directional stimulation. However, it is not fully understood how these segmented leads with reduced electrode size modify the ...
T A Khoa Nguyen +6 more
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The Effect of Unilateral Subthalamic Nucleus Deep Brain Stimulation on Contralateral Subthalamic Nucleus Local Field Potentials [PDF]
Neuromodulation: Technology at the Neural Interface, 2020 Unilateral subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson's disease (PD) improves ipsilateral symptoms, but how this occurs is not well understood. We investigated whether unilateral STN DBS suppresses contralateral STN beta activity in the local field potential (LFP), since previous research has shown that activity in the beta ...
Fischer, P +6 more
openaire +4 more sources
PLoS ONE, 2018 Anatomical atlases have been developed to improve the targeting of basal ganglia in deep brain stimulation. However, the sole anatomy cannot predict the functional outcome of this surgery.
Claire Haegelen +7 more
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Computational Modeling of Ultrasonic Subthalamic Nucleus Stimulation [PDF]
IEEE Transactions on Biomedical Engineering, 2019 To explore the potential of ultrasonic modulation of plateau-potential generating subthalamic nucleus neurons (STN), by modeling their interaction with continuous and pulsed ultrasonic waves.A computational model for ultrasonic stimulation of the STN is created by combining the Otsuka-model with the bilayer sonophore model.
Thomas Tarnaud +3 more
openaire +3 more sources
Frontiers in NeuroscienceBackgroundParkinson’s disease is associated with increased impulsivity, which can be divided into several domains: motor (consisting of proactive and reactive subdomains), reflection, and cognitive impulsivity.
Martijn Hendriks +10 more
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Neurology Research International, 2011 Dopamine dysregulation syndrome is a complication of the dopaminergic treatment in Parkinson's disease that may be very disabling due to the negative impact that compulsive medication use may have on patients' social, psychological, and physical ...
Beatriz De la Casa-Fages +1 more
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Nomogram for Predicting Depression Improvement after Deep Brain Stimulation for Parkinson’s Disease
Brain Sciences, 2022 Background: Parkinson’s disease is a common neurodegenerative disease, with depression being a common non-motor symptom. Bilateral subthalamic nucleus deep brain stimulation is an effective method for the treatment of Parkinson’s disease.
Bowen Chang +6 more
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