Results 21 to 30 of about 490,973 (323)

The subthalamic nucleus in the context of movement disorders [PDF]

open access: bronzeBrain, 2003
The subthalamic nucleus (STN) has been regarded as an important modulator of basal ganglia output. It receives its major afferents from the cerebral cortex, thalamus, globus pallidus externus and brainstem, and projects mainly to both segments of the globus pallidus, substantia nigra, striatum and brainstem.
Clement Hamani
openalex   +4 more sources

Are there three Subdivisions in the primate Subthalamic Nucleus? [PDF]

open access: yesFrontiers in Neuroanatomy, 2012
The prevailing academic opinion holds that the subthalamic nucleus (STN) consists of three parts, each anatomically distinct and selectively associated with cognitive, emotional, or motor functioning.
Max C Keuken   +7 more
doaj   +8 more sources

The subthalamic nucleus : Part I: Development, cytology, topography and connections [PDF]

open access: yes, 2008
This monograph on the subthalamic nucleus accentuates in Part I the gap between experimental animal and human information concerning subthalamic development, cytology, topography and connections. The light and electron microscopical cytology concerns the
Heida, Tjitske   +3 more
core   +19 more sources

Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers

open access: yesAnnals of Neurology, 2022
This study was undertaken to compare the rate of change in cognition between glucocerebrosidase (GBA) mutation carriers and noncarriers with and without subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson disease.
Gian D Pal   +30 more
semanticscholar   +1 more source

Principles of gait encoding in the subthalamic nucleus of people with Parkinson’s disease

open access: yesScience Translational Medicine, 2022
Disruption of subthalamic nucleus dynamics in Parkinson’s disease leads to impairments during walking. Here, we aimed to uncover the principles through which the subthalamic nucleus encodes functional and dysfunctional walking in people with Parkinson’s ...
Yohann Thenaisie   +16 more
semanticscholar   +1 more source

Sex modulates the outcome of subthalamic nucleus deep brain stimulation in patients with Parkinson’s disease

open access: yesNeural Regeneration Research, 2023
There are many documented sex differences in the clinical course, symptom expression profile, and treatment response of Parkinson’s disease, creating additional challenges for patient management.
Tian-Shuo Yuan   +7 more
doaj   +1 more source

Targeting the Subthalamic Nucleus [PDF]

open access: yesStereotactic and Functional Neurosurgery, 2001
The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN.
Aziz, T   +9 more
openaire   +3 more sources

Effects of bilateral subthalamic nucleus deep brain stimulation on motor symptoms in Parkinson’s disease: a retrospective cohort study

open access: yesNeural Regeneration Research, 2021
Deep brain stimulation of the bilateral subthalamic nucleus (STN) is a therapeutic option for patients with Parkinson’s disease (PD) in whom medical therapies have been ineffective.
Guo-Xiong Cheng   +6 more
doaj   +1 more source

Subthalamic Nucleus Degeneration As A Dark Cause of Parkinson’s Disease Due to Subarachnoid Hemorrhage: A Preliminary Experimental Study

open access: yesJournal of Contemporary Medicine, 2023
Background: Although the subtahalamic nucleus degeneration has been accused of Parkinson’s disease, the obscure roles of subtalamic nucleus degeneration induced by subarachnoid hemorrhages has not been adequately studied.
Mehmet Hakan Şahin, Mete Zeynal
doaj   +1 more source

Deep brain stimulation electrode position impact on parkinsonian non-motor symptoms

open access: yesBiomedical Papers, 2022
Background. In this study we evaluated the impact of location of deep brain stimulation electrode active contact in different parts of the subthalamic nucleus on improvement of non-motor symptoms in patients with Parkinson's disease. Methods.
Jan Bardon   +15 more
doaj   +1 more source

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