Results 21 to 30 of about 40,678 (327)
Deep brain stimulation electrode position impact on parkinsonian non-motor symptoms
Biomedical Papers, 2022 Background. In this study we evaluated the impact of location of deep brain stimulation electrode active contact in different parts of the subthalamic nucleus on improvement of non-motor symptoms in patients with Parkinson's disease. Methods.
Jan Bardon +15 more
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Journal of Contemporary Medicine, 2023 Background: Although the subtahalamic nucleus degeneration has been accused of Parkinson’s disease, the obscure roles of subtalamic nucleus degeneration induced by subarachnoid hemorrhages has not been adequately studied.
Mehmet Hakan Şahin, Mete Zeynal
doaj +1 more source
Neurobiology of Disease, 2023 Background: Recent animal model studies have suggested that the parafascicular nucleus has the potential to be an effective deep brain stimulation target for Parkinson's disease.
Lili Chen +8 more
doaj +1 more source
Potential mechanisms for imperfect synchronization in parkinsonian basal ganglia [PDF]
, 2012 Neural activity in the brain of parkinsonian patients is characterized by the intermittently synchronized oscillatory dynamics. This imperfect synchronization, observed in the beta frequency band, is believed to be related to the hypokinetic motor ...
Park, Choongseok, Rubchinsky, Leonid
core +6 more sources
Imaging of the human subthalamic nucleus
, 2021 The human subthalamic nucleus (STN) is a small lens shaped iron rich nucleus, which has gained substantial interest as a target for deep brain stimulation surgery for a variety of movement disorders. The internal anatomy of the human STN has not been fully elucidated, and an intensive debate, discussing the level of overlap between putative limbic ...
Alkemade, A., Forstmann, B.U.
openaire +4 more sources
The subthalamic nucleus, oscillations, and conflict [PDF]
Movement Disorders, 2015 AbstractThe subthalamic nucleus (STN), which is currently the most common target for deep brain stimulation (DBS) for Parkinson's disease (PD), has received increased attention over the past few years for the roles it may play in functions beyond simple motor control.
Kareem A. Zaghloul +3 more
openaire +3 more sources
PLoS ONE, 2020 BackgroundIn addition to the typical motor symptoms, a majority of patients suffering from Parkinson's disease experience language impairments. Deep Brain Stimulation of the subthalamic nucleus robustly reduces motor dysfunction, but its impact on ...
Felicitas Ehlen +3 more
doaj +1 more source
Brain Stimulation, 2023 Background: Psychiatric comorbidities are common in Parkinson's disease (PD) and may change with high-frequency stimulation targeting the subthalamic nucleus.
Linbin Wang +5 more
doaj +1 more source
The role of the subthalamic nucleus in cognition [PDF]
Reviews in the Neurosciences, 2013 Because the complex functions of the basal ganglia have been increasingly studied over the past several decades, the understanding of the role of the subthalamic nucleus (STN) in motor and cognitive functions has evolved. The traditional role in motor function ascribed to the STN, based on its involvement in the cortico-striato-thalamo-cortical motor ...
Kareem A. Zaghloul, David B. Weintraub
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Transcriptional Profile of the Developing Subthalamic Nucleus
eneuro, 2022 AbstractThe subthalamic nucleus (STN) is a small, excitatory nucleus that regulates the output of basal ganglia motor circuits. The functions of the STN and its role in the pathophysiology of Parkinson’s disease are now well established. However, some basic characteristics like the developmental origin and molecular phenotype of neuronal subpopulations
Ema Bokulić +2 more
openaire +4 more sources