Results 21 to 30 of about 41,423 (288)
Informed consent decision-making in deep brain stimulation [PDF]
, 2018 Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious.
Appelbaum +6 more
core +2 more sources
The subcortical cocktail problem; mixed signals from the subthalamic nucleus and substantia nigra.
PLoS ONE, 2015 The subthalamic nucleus and the directly adjacent substantia nigra are small and important structures in the basal ganglia. Functional magnetic resonance imaging studies have shown that the subthalamic nucleus and substantia nigra are selectively ...
Gilles de Hollander +2 more
doaj +1 more source
Translational Psychiatry, 2022 Patients with psychiatric symptoms, such as depression, anxiety, and visual hallucinations, may be at increased risk for adverse effects following deep brain stimulation of the subthalamic nucleus for Parkinson’s disease, but there have been relatively ...
Ian H. Kratter +7 more
doaj +1 more source
Neuronal Activity in the Human Subthalamic Nucleus Encodes Decision Conflict during Action Selection [PDF]
, 2012 The subthalamic nucleus (STN), which receives excitatory inputs from the cortex and has direct connections with the inhibitory pathways\ud of the basal ganglia, is well positioned to efficiently mediate action selection.
Baltuch, G. H. +5 more
core +2 more sources
Basal ganglia role in learning rewarded actions and executing previously learned choices: Healthy and diseased states [PDF]
, 2020 The basal ganglia (BG) is a collection of nuclei located deep beneath the cerebral cortex that is involved in learning and selection of rewarded actions. Here, we analyzed BG mechanisms that enable these functions.
Atwood, Brady +2 more
core +1 more source
Physical therapy and deep brain stimulation in Parkinson’s Disease: Protocol for a pilot randomized controlled trial [PDF]
, 2018 Background Subthalamic nucleus deep brain stimulation (STN-DBS) reduces tremor, muscle stiffness, and bradykinesia in people with Parkinson’s Disease (PD).
Duncan, Ryan P +4 more
core +2 more sources
Analysis of patient-specific stimulation with segmented leads in the subthalamic nucleus.
PLoS ONE, 2019 ObjectiveSegmented deep brain stimulation leads in the subthalamic nucleus have shown to increase therapeutic window using directional stimulation. However, it is not fully understood how these segmented leads with reduced electrode size modify the ...
T A Khoa Nguyen +6 more
doaj +1 more source
Neurobiology of Disease, 2012 Huntington's disease (HD) is characterized by neuronal loss in the striatum, ultimately leading to an ‘imbalance’ in the electrical activity of the basal ganglia-thalamocortical circuits.
Rinske Vlamings +8 more
doaj +1 more source
PLoS ONE, 2018 Anatomical atlases have been developed to improve the targeting of basal ganglia in deep brain stimulation. However, the sole anatomy cannot predict the functional outcome of this surgery.
Claire Haegelen +7 more
doaj +1 more source
Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits [PDF]
, 2016 Cortico-basal ganglia-thalamic (CBT) neural circuits are critical modulators of cognitive and motor function. When compromised, these circuits contribute to neurological and psychiatric disorders, such as Parkinson's disease (PD).
Bucklin, Mark +5 more
core +1 more source