Results 51 to 60 of about 488,438 (323)
Hitting the brakes: pathological subthalamic nucleus activity in Parkinson's disease gait freezing.
Brain : a journal of neurology, 2019 Gait freezing is a complex and devastating paroxysmal motor arrest commonly suffered in Parkinson's disease that causes significant impairment to mobility, commonly resulting in falls and subsequent injury.
M. Georgiades +6 more
semanticscholar +1 more source
Alternating Modulation of Subthalamic Nucleus Beta Oscillations during Stepping
Journal of Neuroscience, 2018 Gait disturbances in Parkinson's disease are commonly refractory to current treatment options and majorly impair patient's quality of life. Auditory cues facilitate gait and prevent motor blocks.
P. Fischer +18 more
semanticscholar +1 more source
Unsupervised Detection of Sub-Territories of the Subthalamic Nucleus During DBS Surgery with Manifold Learning [PDF]
arXiv, 2022 During Deep Brain Stimulation(DBS) surgery for treating Parkinson's disease, one vital task is to detect a specific brain area called the Subthalamic Nucleus(STN) and a sub-territory within the STN called the Dorsolateral Oscillatory Region(DLOR). Accurate detection of the STN borders is crucial for adequate clinical outcomes.
arxiv
Subthalamic Nucleus and Sensorimotor Cortex Activity During Speech Production
Journal of Neuroscience, 2018 The sensorimotor cortex is somatotopically organized to represent the vocal tract articulators such as lips, tongue, larynx, and jaw. How speech and articulatory features are encoded at the subcortical level, however, remains largely unknown. We analyzed
A. Chrabaszcz +13 more
semanticscholar +1 more source
Neurology Research International, 2011 Dopamine dysregulation syndrome is a complication of the dopaminergic treatment in Parkinson's disease that may be very disabling due to the negative impact that compulsive medication use may have on patients' social, psychological, and physical ...
Beatriz De la Casa-Fages +1 more
doaj +1 more source
Intermittent synchronization in a network of bursting neurons [PDF]
Chaos, 21, 033125, 2011, 2011 Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical network of the basal ganglia, formed by excitatory and inhibitory bursters of the subthalamic nucleus and globus ...
arxiv +1 more source
Subthalamic Nucleus Deep Brain Stimulation: Basic Concepts and Novel Perspectives
eNeuro, 2017 Over the last decades, extensive basic and clinical knowledge has been acquired on the use of subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson’s disease (PD). It is now clear that mechanisms involved in the effects of this therapy are
C. Hamani +9 more
semanticscholar +1 more source
New England Journal of Medicine, 2003 BACKGROUND Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease have been well documented, the long-term outcomes of the procedure are unknown.
P. Krack +11 more
semanticscholar +1 more source
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
Neurobiology of Disease, 2023 Background: Recent animal model studies have suggested that the parafascicular nucleus has the potential to be an effective deep brain stimulation target for Parkinson's disease.
Lili Chen +8 more
doaj