Results 51 to 60 of about 502,362 (345)
Basal ganglia role in learning rewarded actions and executing previously learned choices: Healthy and diseased states [PDF]
, 2020 The basal ganglia (BG) is a collection of nuclei located deep beneath the cerebral cortex that is involved in learning and selection of rewarded actions. Here, we analyzed BG mechanisms that enable these functions.
Atwood, Brady +2 more
core +1 more source
Neurobiology of Disease, 2012 Huntington's disease (HD) is characterized by neuronal loss in the striatum, ultimately leading to an ‘imbalance’ in the electrical activity of the basal ganglia-thalamocortical circuits.
Rinske Vlamings +8 more
doaj +1 more source
Pallidal versus subthalamic nucleus deep brain stimulation for levodopa‐induced dyskinesia
Annals of Clinical and Translational Neurology, 2019 To compare the efficacy of subthalamic nucleus (STN) and globus pallidus internus (GPi) deep brain stimulation (DBS) on reducing levodopa‐induced dyskinesia (LID) in Parkinson’s disease, and to explore the potential underlying mechanisms.
Shiying Fan +11 more
semanticscholar +1 more source
Aversion encoded in the subthalamic nucleus
bioRxiv, 2020 Activation of the subthalamic nucleus (STN) is associated with the stopping of ongoing behavior via the basal ganglia. However, we recently observed that optogenetic STN excitation induced a strong jumping/escaping behavior.
G. Serra +4 more
semanticscholar +1 more source
Hitting the brakes: pathological subthalamic nucleus activity in Parkinson's disease gait freezing.
Brain : a journal of neurology, 2019 Gait freezing is a complex and devastating paroxysmal motor arrest commonly suffered in Parkinson's disease that causes significant impairment to mobility, commonly resulting in falls and subsequent injury.
M. Georgiades +6 more
semanticscholar +1 more source
Frontiers in NeuroscienceBackgroundParkinson’s disease is associated with increased impulsivity, which can be divided into several domains: motor (consisting of proactive and reactive subdomains), reflection, and cognitive impulsivity.
Martijn Hendriks +10 more
doaj +1 more source
Totally Implantable Bidirectional Neural Prostheses: A Flexible Platform for Innovation in Neuromodulation. [PDF]
, 2018 Implantable neural prostheses are in widespread use for treating a variety of brain disorders. Until recently, most implantable brain devices have been unidirectional, either delivering neurostimulation without brain sensing, or sensing brain activity to
Starr, Philip A
core +2 more sources
Nomogram for Predicting Depression Improvement after Deep Brain Stimulation for Parkinson’s Disease
Brain Sciences, 2022 Background: Parkinson’s disease is a common neurodegenerative disease, with depression being a common non-motor symptom. Bilateral subthalamic nucleus deep brain stimulation is an effective method for the treatment of Parkinson’s disease.
Bowen Chang +6 more
doaj +1 more source
Neurosystems: brain rhythms and cognitive processing [PDF]
, 2013 Neuronal rhythms are ubiquitous features of brain dynamics, and are highly correlated with cognitive processing. However, the relationship between the physiological mechanisms producing these rhythms and the functions associated with the rhythms remains ...
Börgers, Christoph +6 more
core +1 more source
Subthalamic Nucleus Deep Brain Stimulation Evokes Resonant Neural Activity
Annals of Neurology, 2018 Deep brain stimulation (DBS) is a rapidly expanding treatment for neurological and psychiatric conditions; however, a target‐specific biomarker is required to optimize therapy.
N. Sinclair +7 more
semanticscholar +1 more source