Results 71 to 80 of about 40,678 (327)
Effect of subthalamic deep brain stimulation on gait in patients with advanced Parkinson’s disease
Retos: Nuevas Tendencias en Educación Física, Deportes y RecreaciónIntroduction: Advanced Parkinson's disease severely affects gait. According to literature, deep brain stimulation of the subthalamic nucleus has scarce impact on gait in this disease.
Juan F. Mier-García +8 more
doaj +1 more source
Imaging the Centromedian Thalamic Nucleus Using Quantitative Susceptibility Mapping. [PDF]
, 2019 The centromedian (CM) nucleus is an intralaminar thalamic nucleus that is considered as a potentially effective target of deep brain stimulation (DBS) and ablative surgeries for the treatment of multiple neurological and psychiatric disorders.
Gutierrez, Lorenzo +9 more
core
Annals of Neurology, EarlyView.Objective The objective of this study was to investigate the relationships among subthalamic nucleus (STN) activity, gait initiation (GI), and freezing of gait (FOG) in patients with Parkinson's disease (PD). Methods We recorded GI and STN local field potentials (LFPs) via externalized cables in 38 patients with PD (35 reporting FOG in daily life ...
Antoine Collomb‐Clerc +12 more
wiley +1 more source
Trials, 2011 Background Severe gait disturbances in idiopathic Parkinson's disease (PD) are observed in up to 80% of all patients in advanced disease stages with important impact on quality of life.
Fritz Melanie +7 more
doaj +1 more source
Subthalamic nucleus high-frequency stimulation restores altered electrophysiological properties of cortical neurons in parkinsonian rat. [PDF]
PLoS ONE, 2013 Electrophysiological recordings performed in parkinsonian patients and animal models have confirmed the occurrence of alterations in firing rate and pattern of basal ganglia neurons, but the outcome of these changes in thalamo-cortical networks remains ...
Bertrand Degos +3 more
doaj +1 more source
Selective stimulation of the subthalamic nucleus [PDF]
, 2013 Parkinson's disease (PD) is the second most common neurodegenerative disorder. In 2008, about 30.000 PD patients were registered at hospitals in the Netherlands. The number of PD patients is expected to increase by 47% from 2005 to 2025. PD is characterized by several motor related symptoms including tremor, bradykinesia, i.e.
openaire +3 more sources
Deep brain stimulation of the subthalamic nucleus modulates sensitivity to decision outcome value in Parkinson's disease. [PDF]
, 2016 Deep brain stimulation (DBS) of the subthalamic nucleus in Parkinson's disease is known to cause a subtle but important adverse impact on behaviour, with impulsivity its most widely reported manifestation.
, +6 more
core +3 more sources
Annals of Neurology, EarlyView.Objective In Parkinson's disease (PD), the power of beta oscillations (± 13–30 hertz [Hz]) from subthalamic nucleus (STN) local field potentials (LFPs) is associated with motor symptoms. Beta power can be used for adaptive deep brain stimulation (aDBS) algorithms based upon symptom fluctuations.
Martijn G.J. de Neeling +8 more
wiley +1 more source
Parkinson's Disease, 2020 Background. Treatment of freezing of gait (FOG) is always challenging because of its unpredictable nature and multifactorial physiopathology. Intestinal levodopa infusion has been proposed in recent years as a valuable option for its improvement.
Belén González-Herrero +4 more
doaj +1 more source
Dopamine-dependent scaling of subthalamic gamma bursts with movement velocity in patients with Parkinson’s disease [PDF]
, 2018 Gamma synchronization increases during movement and scales with kinematic parameters. Here, disease-specific characteristics of this synchronization and the dopamine-dependence of its scaling in Parkinson’s disease are investigated.
Bock, Antje +8 more
core +1 more source