Results 81 to 90 of about 502,362 (345)

Causal role for the subthalamic nucleus in interrupting behavior

eLife, 2017
Stopping or pausing in response to threats, conflicting information, or surprise is fundamental to behavior. Evidence across species has shown that the subthalamic nucleus (STN) is activated by scenarios involving stopping or pausing, yet evidence that ...
Kathryn H Fife, Navarre Gutierrez‐Reed, Vivien Zell, Julie Bailly, Christina M Lewis, A. Aron, T. Hnasko   +6 more
semanticscholar   +1 more source

Quantitative analysis of language production in Parkinson's disease using a cued sentence generation task [PDF]

, 2012
The present study examined language production skills in Parkinson's disease (PD) patients. A unique cued sentence generation task was created in order to reduce demands on memory and attention.
Corthals, Paul, De Letter, Miet, Santens, Patrick, Van Borsel, John, Vanhoutte, Sarah   +4 more
core   +1 more source

Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia

Annals of Neurology, EarlyView.
Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani, Shiro Horisawa, Konstantin Butenko, Hiroki Togo, Arun Garimella, William Drew, Melissa Chua, Esraa Shaban, Takakazu Kawamata, Takaomi Taira, Andreas Horn, Michael D. Fox, Takashi Hanakawa   +12 more
wiley   +1 more source

Intestinal Levodopa/Carbidopa Infusion as a Therapeutic Option for Unresponsive Freezing of Gait after Deep Brain Stimulation in Parkinson’s Disease

Parkinson's Disease, 2020
Background. Treatment of freezing of gait (FOG) is always challenging because of its unpredictable nature and multifactorial physiopathology. Intestinal levodopa infusion has been proposed in recent years as a valuable option for its improvement.
Belén González-Herrero, Serge Jauma-Classen, Roser Gómez-Llopico, Gerard Plans, Matilde Calopa   +4 more
doaj   +1 more source

Subthalamic nucleus deep brain stimulation is neuroprotective in the A53T α‐synuclein Parkinson's disease rat model

Annals of Neurology, 2017
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective symptomatic therapy for motor deficits in Parkinson's disease (PD).
T. Musacchio, Maike Rebenstorff, F. Fluri, J. Brotchie, J. Volkmann, J. Koprich, C. Ip   +6 more
semanticscholar   +1 more source

Hominoid‐specific calretinin‐immunopositivity of the optic radiation (geniculocalcarine tract)

The Anatomical Record, EarlyView.
Calretinin‐immunostained coronal section through the primary (V1) and extrastriate (ExSt) cortex of the lar gibbon. Note that the optic radiation (OR) is strongly calretinin‐immunoreactive. This calretinin‐immunopositivity of the OR distinguishes the Hominoidea from other primates in terms of the neurochemistry of the OR.
Nelyane N. M. Santana, Jordan Swiegers, Mads F. Bertelsen, Chet C. Sherwood, José R. L. P. Cavalcanti, Paul R. Manger   +5 more
wiley   +1 more source

Subthalamic Nucleus and Sensorimotor Cortex Activity During Speech Production

Journal of Neuroscience, 2018
The sensorimotor cortex is somatotopically organized to represent the vocal tract articulators such as lips, tongue, larynx, and jaw. How speech and articulatory features are encoded at the subcortical level, however, remains largely unknown. We analyzed
A. Chrabaszcz, W. Neumann, Otilia Stretcu, W. Lipski, A. Bush, C. Dastolfo-Hromack, Dengyu Wang, D. Crammond, S. Shaiman, M. Dickey, L. Holt, R. Turner, J. Fiez, R. Richardson   +13 more
semanticscholar   +1 more source

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

Clinical Anatomy, EarlyView.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley, Brooke Willoughby, Alexandra L. Webb, Natasha A. M. S. Flack, Laura Y. Whitburn   +4 more
wiley   +1 more source

Sweetspot Mapping in Deep Brain Stimulation: Strengths and Limitations of Current Approaches

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Open questions remain regarding the optimal target, or sweetspot, for deep brain stimulation (DBS) in, for example, Parkinson's disease. Previous studies introduced different methods of mapping DBS effects to determine sweetspots. While having a direct impact on surgical targeting and postoperative programming in DBS, these methods ...
Till A. Dembek, Juan Carlos Baldermann, Jan‐Niklas Petry‐Schmelzer, Hannah Jergas, Harald Treuer, Veerle Visser‐Vandewalle, Haidar S. Dafsari, Michael T. Barbe   +7 more
wiley   +1 more source

Indirect Targeting of Subthalamic Deep Brain Stimulation Guided by Stereotactic Computed Tomography and Microelectrode Recordings in Patients With Parkinson’s Disease

Frontiers in Human Neuroscience, 2018
Objective: Magnetic resonance imaging fusion techniques guided by frame-based stereotactic computed tomography and microelectrode recordings are widely used to target the subthalamic nucleus. However, MRI is not always available.
Po-Hsun Tu, Zhuo-Hao Liu, Chiung Chu Chen, Chiung Chu Chen, Wey Yil Lin, Wey Yil Lin, Wey Yil Lin, Amy L. Bowes, Chin Song Lu, Chin Song Lu, Shih-Tseng Lee   +10 more
doaj   +1 more source