Results 81 to 90 of about 41,423 (288)

Subthalamic nucleus stabilizes movements by reducing neural spike variability in monkey basal ganglia

Nature Communications, 2022
Chemogenetic inactivation of the subthalamic nucleus in monkeys increases spike train variability in the pallidum and prolongs movement time, suggesting its role in stabilizing pallidal spike trains to achieve stable motor control.
Taku Hasegawa, Satomi Chiken, Kenta Kobayashi, Atsushi Nambu   +3 more
doaj   +1 more source

Cortical and Striatal Circuits in Huntington's Disease

, 2020
Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms.
Blumenstock, S., Dudanova, I.
core   +1 more source

Closed-loop deep brain stimulation based on a stream-clustering system [PDF]

, 2019
Idiopathic Parkinsons disease (PD) is currently the second most important neurodegenerative disease in incidence. Deep brain stimulation (DBS) constitutes a successful and necessary therapy; however, the continuous stimulation it provides can be ...
Aziz, Tipu, Bruna, R, Camara, Carmen, Pereda, E, Warwick, Kevin   +4 more
core   +1 more source

Thalamic Deep Brain Stimulation for Dystonic Head Tremor: A Long‐Term Study of 18 Patients

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dystonic head tremor is a particular manifestation of dystonia, which is difficult to treat. Although deep brain stimulation (DBS) of the globus pallidus internus has been established as a treatment for different phenotypes of dystonia, its role in dystonic tremor has been debated.
Johanna M. Nagel, Marc E. Wolf, Christian Blahak, Joachim Runge, Christoph Schrader, Dirk Dressler, Assel Saryyeva, Joachim K. Krauss   +7 more
wiley   +1 more source

Subcortical correlates of consciousness with human single neuron recordings

eLife
Subcortical brain structures such as the subthalamic nucleus or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness remains unclear, due to the inherent difficulties of recording ...
Michael Pereira, Nathan Faivre, Fosco Bernasconi, Nicholas Brandmeir, Jacob E Suffridge, Kaylee Tran, Shuo Wang, Victor Finomore, Peter Konrad, Ali Rezai, Olaf Blanke   +10 more
doaj   +1 more source

One Side or Two? A Systematic Review of Deep Brain Stimulation Approaches in Movement Disorders

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established treatment for movement disorders such as Parkinson's disease (PD) and essential tremor (ET). However, the decision between unilateral, staged bilateral, or simultaneous bilateral DBS remains controversial, influenced by clinical presentation, patient preferences, and economic factors ...
Artur Vetkas, Andrew Yang, Alexandre Boutet, Cletus Cheyuo, Brendan Santyr, Can Sarica, Benjamin Davidson, Anton Fomenko, Nardin Samuel, Stefan Lang, Srdjan Sumarac, Luka Milosevic, Taufik Valiante, Mojgan Hodaie, Suneil K. Kalia, Andres M. Lozano   +15 more
wiley   +1 more source

Cognitive Outcome After Deep Brain Stimulation for Refractory Obsessive–Compulsive Disorder: A Systematic Review

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Introduction Deep brain stimulation (DBS) is an effective treatment for refractory obsessive–compulsive disorder (OCD). Neuropsychological assessment contributes to DBS treatment in several ways: it monitors the cognitive safety of the treatment, identifies beneficial or detrimental cognitive side effects and it could aid to explain ...
Tim A. M. Bouwens van der Vlis, Annelien Duits, Mégan M. G. H. van de Veerdonk, Anne E. P. Mulders, Koen R. J. Schruers, Yasin Temel, Linda Ackermans, Albert F. G. Leentjens   +7 more
wiley   +1 more source

Effects of aging on nitrergic neurons in human striatum and subthalamic nucleus

Arquivos de Neuro-Psiquiatria, 2015
Nitric oxide (NO) is a major neurotransmitter associated with motor control in basal ganglia. Movement disorders, as essential tremor and Parkinson’s disease, are more prevalent on aged individuals.
Bruno Lopes dos Santos-Lobato, Elaine Aparecida Del-Bel, José Eymard Homem Pittella, Vitor Tumas   +3 more
doaj   +1 more source

Examining Device Usage Patterns in Outpatient Telemedicine Video Visits among Movement Disorders Patients

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Telemedicine has improved access to care, yet device usage for virtual visits remains underexplored. Objective To characterize device usage patterns for video televisits across sociodemographic factors in a tertiary Movement Disorders clinic in the United States.
Mitra Afshari, Vijay G. Palakuzhy, Bichun Ouyang, Glenn T. Stebbins, Christopher G. Goetz   +4 more
wiley   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source