Results 91 to 100 of about 25,546 (199)

Evolution of a subtilisin-like protease gene family in the grass endophytic fungus Epichloë festucae

BMC Evolutionary Biology, 2009
Background Subtilisin-like proteases (SLPs) form a superfamily of enzymes that act to degrade protein substrates. In fungi, SLPs can play either a general nutritive role, or may play specific roles in cell metabolism, or as pathogenicity or virulence ...
Hesse Uljana, Schardl Christopher L, Bryant Michelle K, Scott Barry   +3 more
doaj   +1 more source

Stimulation of bioprocesses by ultrasound [PDF]

, 2011
Ultrasound (US) has become a ubiquitous technological process in a large variety of scientific disciplines. However, little information exists on the use of ultrasound to enhance biological processes and/or processing and consequently this paper provides
Akunna, Joseph C., Bennett, Jason, Bremner, David H., Kwiatkowska, Barbara, Walker, Graeme M.   +4 more
core   +3 more sources

Understanding how enzymes work: the journey to ensemble–function studies

The FEBS Journal, EarlyView.
For decades, structure–function has dominated biochemistry. Structures are highly valuable, yet more is needed to achieve a quantitative understanding of biomolecular function, because function emerges from an ensemble of states, rather than a static structure. We describe an ensemble–function framework applied to quantitatively dissect serine protease
Daniel Herschlag, Siyuan Du
wiley   +1 more source

The usefulness of rabbit anti-QQQPP peptide antibodies to wheat flour antigenicity studies

Czech Journal of Food Sciences, 2008
The aim of our work was to estimate the usefulness of rabbit polyclonal anti-QQQPP peptide antibodies to determination of gluten proteins and the usage of these antibodies to estimate the changes of allergenicity of wheat flour after enzymatic ...
Joanna Leszczyńska, Agata Łącka, Malgorzata Bryszewska, Ewa Brzezińska-Błaszczyk   +3 more
doaj   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Encounter complexes and dimensionality reduction in protein-protein association [PDF]

, 2014
An outstanding challenge has been to understand the mechanism whereby proteins associate. We report here the results of exhaustively sampling the conformational space in protein–protein association using a physics-based energy function.
Beglov, D., Clore, G. M., Hall, D., Kozakov, D., Li, K., Paschalidis, Ioannis Ch., Schueler-Furman, O., Vajda, S., Vakili, P., Zheng, J.   +9 more
core   +2 more sources

Practical recommendations for treating patients with chronic kidney disease in Australia: a multidisciplinary approach

Internal Medicine Journal, EarlyView.
Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich, W. P. Abhayaratna, R. Audehm, E. I. Ekinci, R. J. MacIsaac, A. J. Nelson, A. Sharma, C. Pollock   +7 more
wiley   +1 more source

Elevated serum galectin‐3 levels predict the incidence of type 2 diabetes mellitus in a Japanese general population: A 10‐year follow‐up study

Journal of Diabetes Investigation, EarlyView.
Elevated serum galectin‐3 levels are associated with the incidence of T2DM independent of insulin resistance, particularly among non‐obese individuals. There may be a diabetogenic mechanism that is not mediated by obesity or insulin resistance. ABSTRACT Aims/Introduction Although several studies have reported elevated serum galectin‐3 levels in type 2 ...
Harumi Takubo‐Yoshimura, Mika Enomoto, Ako Fukami, Nagisa Morikawa, Yume Nohara‐Shitama, Hiromi Sato, Mayo Shimoyama‐Yamamoto, Hisashi Adachi, Yoshihiro Fukumoto   +8 more
wiley   +1 more source

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. [PDF]

, 1990
Extracts from BSC-40 cells infected with vaccinia recombinants expressing either the yeast KEX2 prohormone endoprotease or a human structural homologue (fur gene product) contained an elevated level of a membrane-associated endoproteolytic activity that ...
Barr, P, Brake, A, Bresnahan, P, Gibson, H, Leduc, R, Thomas, G, Thomas, L, THORNER, Jeremy W.   +7 more
core   +1 more source

A stage‐dependent seed defense response to explain efficient seed transmission of Xanthomonas citri pv. fuscans to common bean

Plant, Cell &Environment, EarlyView.
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse, Łukasz Paweł Tarkowski, Martial Briand, David Lalanne, Nicolas W. G. Chen, Matthieu Barret, Jerome Verdier   +6 more
wiley   +1 more source