Results 61 to 70 of about 54,156 (279)

Biosynthesis and enzymology of the Caenorhabditis elegans cuticle: identification and characterization of a novel serine protease inhibitor. [PDF]

, 2006
The nematode Caenorhabditis elegans represents an excellent model in which to examine nematode gene expression and function. A completed genome, straightforward transgenesis, available mutants and practical genome-wide RNAi approaches provide an ...
Andrew J. Birnie, Antony P. Page, Brenner, Brooks, Canty, Chu, Davis, Edens, Eschenlauer, Frand, Friedman, Gillian McCormack, Hawdon, Hill, Johnstone, Kamath, Kamath, Kramerova, Kramerova, Kress, Lustigman, Milstone, Myllyharju, Myllyharju, Novelli, Page, Page, Page, Page, Page, Pappano, Peters, Poole, Roberts, Sapio, Simmer, Singh, Sulston, Thacker, Thacker, Thein, Winter, Yang   +42 more
core   +1 more source

New insights into the evolution of subtilisin-like serine protease genes in Pezizomycotina

BMC Evolutionary Biology, 2010
Background Subtilisin-like serine proteases play an important role in pathogenic fungi during the penetration and colonization of their hosts. In this study, we perform an evolutionary analysis of the subtilisin-like serine protease genes of subphylum ...
Zhang Ying, Liang Lianming, Yu Zefen, Tian Baoyu, Dong Linqian, Yang Jinkui, Yu Li, Li Juan, Wang Xu, Zhang Keqin   +9 more
doaj   +1 more source

Cloning and characterisation of two subtilisin-like protease genes from Neotyphodium lolii : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Genetics at Massey University [PDF]

, 2000
PCR amplification of Neotyphodium lolii genomic DNA with degenerate primers detected two different sequences with homology to subtilisin-like proteases. These two PCR products were used to screen a N. lolii Lp19 genomic library.
McGill, Michelle Kay
core  

Entropic Landscape: the method to predict folding patterns and regional stability of proteins [PDF]

, 2009
I propose a new method to calculate the entropy of a given protein sequence fragment. The set of fragment entropies over all possible fragments of the given sequence shows which region of the sequence is statistically stable and which region has a strong
Kentaro Onizuka
core   +2 more sources

Fluorescent derivatization of a protease antigen to track antigen uptake and processing in human cell lines

BMC Immunology, 2004
Background We have devised a simple and efficient fluorescence-based method to track antigen uptake and processing in human B lymphoblastoid cells (B-LCL).
Collier Katherine D, Wong David L, Patil Namrata S, McDonald Hugh C   +3 more
doaj   +1 more source

Determination of selenium speciation in the muscle, kidney, and liver from different animals treated with different selenium supplements by HPLC‐ICP‐MS

Animal Research and One Health, EarlyView.
Dietary selenium (Se) deficiency is recognized as a global problem, and exogenous Se supplementation can effectively enrich its levels in animal bodies. Offal tissues are equally important as meat in Se enrichment. Varying properties among Se species require information beyond total Se concentration to fully evaluate health risk/benefits.
Xiaoqing Guo, Xueting Jia, Kai Zhang, Chaohua Tang, Xueyang Si, Bo He, Manus Carey, Lynda S. Perkins, Qingyu Zhao, Junmin Zhang   +9 more
wiley   +1 more source

Estimation of flattening coefficient for absorption and circular dichroism using simulation [PDF]

, 2009
The absorbance and circular dichroism (CD) of suspensions is lower than if the same amount of chromophore were uniformly distributed throughout the medium. Several mathematical treatments of this absorption flattening phenomenon have been presented using
Braun, Bustamante, Castiglioni, Castiglioni, Castiglioni, Castillo, Duysens, Ganesan, Gordon, Kelly, Latimer, Naqvi, Peter J. Halling, Sarmento, Teeters, Urry, Wallace, Wallace, Wittung   +18 more
core   +1 more source

Interaction of subtilisins with serpins [PDF]

Protein Science, 1996
AbstractSerpins are well‐characterized inhibitors of the chymotrypsin family serine proteinases. We have investigated the interaction of two serpins with members of the subtilisin family, proteinases that possess a similar catalytic mechanism to the chymotrypsins, but a totally different scaffold.
T, Komiyama, H, Grøn, P A, Pemberton, G S, Salvesen   +3 more
openaire   +2 more sources

Machine learning‐based prediction of elevated N terminal pro brain natriuretic peptide among US general population

ESC Heart Failure, Volume 12, Issue 2, Page 859-868, April 2025.
Abstract Aims Natriuretic peptide‐based pre‐heart failure screening has been proposed in recent guidelines. However, an effective strategy to identify screening targets from the general population, more than half of which are at risk for heart failure or pre‐heart failure, has not been well established.
Yuichiro Mori, Shingo Fukuma, Kyohei Yamaji, Atsushi Mizuno, Naoki Kondo, Kosuke Inoue   +5 more
wiley   +1 more source

A molecular modeling approach for structure-based virtual screening and identification of novel anti-hypercholesterolemic agents from Grape

Informatics in Medicine Unlocked, 2022
Hypercholesterolemia is a potential cardiovascular hazard that requires immediate therapeutic intervention. Research has shown that 3-Hydroxy-3-methylglutaryl- CoA reductase (HMG CoA reductase) and Proprotein convertase subtilisin/kexin type 9 (PCSK9 ...
Precious A. Akinnusi, Samuel O. Olubode, Adebowale A. Alade, Samad A. Ahmed, Susan F. Ayekolu, Taiwo M. Ogunlade, Damilola J. Gbore, Olayemi D. Rotimi, Abigail O. Ayodele   +8 more
doaj   +1 more source