Results 51 to 60 of about 621,209 (319)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Error analysis in fraction addition and subtraction using structured observed learning outcomes

African Journal of Teacher Education and Development
Background: Fractions are important because of their critical role in more advanced mathematics. While they are central to mathematics learning, they pose a challenge to learners.
Alphius Dube, Jeremiah S. Maseko
doaj   +1 more source

Algoritma Berhitung Blija ̂h: Alternatif Pembelajaran Operasi Penjumlahan dan Pengurangan

Aksioma: Jurnal Program Studi Pendidikan Matematika, 2018
The aim of this study was to describe arithmetic algorithm on transaction em­ployed by Blij h. The study was a qualitative approach by means of case study in Madurese community. The data were gathered through observation and interviews.
Loviga Denny Pratama, Wahyu Setyaningrum
doaj   +1 more source

An Ingenious Design of a High Performance-Low Complexity Image Compressor for Wireless Capsule Endoscopy

Sensors, 2020
Wireless Capsule Endoscopy is a state-of-the-art technology for medical diagnoses of gastrointestinal diseases. The amount of data produced by an endoscopic capsule camera is huge.
Ioannis Intzes, Hongying Meng, John Cosmas   +2 more
doaj   +1 more source

Exponential Renormalization II: Bogoliubov's R-operation and momentum subtraction schemes

, 2012
This article aims at advancing the recently introduced exponential method for renormalisation in perturbative quantum field theory. It is shown that this new procedure provides a meaningful recursive scheme in the context of the algebraic and group ...
Collins J., Frédéric Patras, Itzykson C., Kurusch Ebrahimi-Fard, Mackey G. W., Smirnov V. A., Zavialov O. I., Zimmermann W.   +7 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Selection of the Better Dual-Timed Up and Go Cognitive Task to Be Used in Patients With Stroke Characterized by Subtraction Operation Difficulties

Frontiers in Neurology, 2020
Background: The Timed Up and Go Test (TUG) with serial subtraction is commonly used to assess cognitive-dual task performance during walking for fall prediction.
Ampha Pumpho, Ampha Pumpho, Nithinun Chaikeeree, Vitoon Saengsirisuwan, Rumpa Boonsinsukh   +4 more
doaj   +1 more source

Subtraction terms for one-loop amplitudes with one unresolved parton

, 2003
Fully differential next-to-next-to-leading order calculations require a method to cancel infrared singularities. In a previous publication, I discussed the general setup for the subtraction method at NNLO.
A. Gehrmann-De Ridder, C. Anastasiou, C. Anastasiou, C. Bauer, D.A. Kosower, D.A. Kosower, D.A. Kosower, D.A. Kosower, E.W.N. Glover, J.M. Campbell, J.M. Campbell, L. Phaf, L.J. Dixon, L.W. Garland, L.W. Garland, S. Catani, S. Catani, S. Catani, S. Catani, S. Dittmaier, S. Frixione, S. Moch, S. Weinzierl, S. Weinzierl, S. Weinzierl, S. Weinzierl, Stefan Weinzierl, T. Matsuura, T. Matsuura, Z. Bern, Z. Bern, Z. Bern, Z. Bern, Z. Bern, Z. Nagy   +34 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source