Results 91 to 100 of about 1,067,207 (315)
Expanded Indications of Molecular-Targeted Drugs in Perioperative Therapy of Breast Cancer
Tokyo Women's Medical University JournalIn recent years, numerous molecular-targeted drugs have become available for the perioperative therapy of breast cancer, bringing about a revolution in breast cancer treatment.
Eiichiro Noguchi, Sadako Akashi-Tanaka
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
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Инфекция и иммунитет, 2016 According to WHO data about 3% of population are infected by hepatitic C virus (HCV) worldwide. Chronic hepatitis C is the leading cause of cirrhosis and hepatocellular carcinoma, thus it becoming one of the global public health problems.
A. V. Semenov +6 more
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Mathematical Structures in Computer Science, 1992 Subtyping in the presence of recursive types for the λ-calculus was studied by Amadio and Cardelli in 1991 (Amadio and Cardelli 1991). In that paper they showed that the problem of deciding whether one recursive type is a subtype of another is decidable in exponential time. In this paper we give an 0(n2) algorithm.
Schwartzbach, Michael Ignatieff +2 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
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<p>Subtype-WGME uses genome-wide gene expression, miRNA, copy number and mutation data from PCAWG as input. It is an auto-encoder (VAE) framework using MLP-Mixer as the backbone encoder.
Liang Zhao, Yang Yang, Zhe Wang
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Cancer subtype identification pipeline: a classifusion approach [PDF]
, 2016 Classification of cancer patients into treatment groups is essential for appropriate diagnosis to increase survival. Previously, a series of papers, largely published in the breast cancer domain have leveraged Computational Intelligence (CI) developments
Agrawal, U. +8 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
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VirusesThe HIV-1 pandemic, spanning four decades, presents a significant challenge to global public health. This study aimed to understand the molecular transmission characteristics of newly reported HIV infections in Taiyuan, Shanxi Province, China, to analyze
Ruihong Gao +7 more
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Archives of the Balkan Medical Union, 2020 Introduction. Blastocystis sp. is a common protozoan parasite that colonizes the intestinal tract of humans and animals and in humans nine subtypes have been described so far.
Martin P. LALEV +3 more
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