Results 81 to 90 of about 1,160,550 (308)

Scatter plots of FC of subtype C amplicons recombined in subtype B and subtype C backbones.

, 2013
(A–D) X-axis: Subtype B and Y-axis: subtype C for 1346 pairs; Black line x = y; (A) all drug classes (R2 = 0.88); (B) NRTIs (R2 = 0.88); (C) NNRTIs (R2 = 0.90); (D) PIs (R2 = 0.87); (E) Analysis of the pair-wise comparison of differences in FCs per clone
David Nauwelaers (350953), Bart Winters (350954), Kurt Van Baelen (350955), Lieven J. Stuyver (249761), Rachelle Bonesteel (350959), Ellen Chi (350956), Derek Steiner (350958), Margriet Van Houtte (326880), Mimi Zhou (350957), Kim Steegen (326871), Colin Aston (350960)   +10 more
core   +1 more source

Cryptosporidium parvum – zoonotic subtype IIdA15G1 in a Slovakian patient [PDF]

, 2020
Introduction and objectives. The parasite Cryptosporidium spp. is an intracellular protozoa which has a broad range of hosts and zoonotic potential. It presents a serious health risk for agricultural workers and veterinarians. The aim of the study was to
Kacirova, J., Madar, M., Barbusinova, E., Strkolcova, G., Goldova, M., Mravcova, K., Mucha, R., Jana Kačírová, Eva Barbušinová, Mária Goldová, Rastislav Mucha, Kristína Mravcová, Gabriela Štrkolcová, Marián Maďar   +13 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A_2A Receptor

, 2019
Among class A G protein-coupled receptors (GPCR), the human adenosine A2A receptor (hA2AAR) remains an attractive drug target. However, translation of A2AAR ligands into the clinic has proved challenging and an improved understanding of A2AAR ...
Barrie Kellam (1280532), Leigh A. Stoddart (1451152), Nicholas D. Kindon (2393749), Eleonora Comeo (8270664), Laura E. Kilpatrick (8270670), Peter J. Scammells (694050), Stephen J. Hill (481670), Mark Soave (8270667)   +7 more
core   +2 more sources

Addressing the Unmet Need in Acne Management: A Novel Dermocosmetics Guideline Tailored to Asian Patient Subgroups

Cosmetics
Acne, a commonly treated skin disease, requires control of one’s daily routine for an optimal outcome. As skincare products continue to advance, and with the introduction of dermocosmetics (active cosmetics, functional cosmetics, cosmeceuticals), it is ...
Hei Sung Kim, Joo Yeon Ko, Dong Hye Suh, Hwa Jung Ryu, Eunsun Baek, Soyun Cho   +5 more
doaj   +1 more source

Classification of Subtypes of Vernal Keratoconjunctivitis by Cluster Analysis Based on Clinical Features

Clinical Ophthalmology, 2023
Hideaki Fujita, Tomohiro Ueno, Shuji Suzuki, Kazuhiro Harada, Tomoko Tsukahara-Kawamura, Hiroaki Ozaki, Eiichi Uchio Department of Ophthalmology, Fukuoka University School of Medicine, Fukuoka, JapanCorrespondence: Eiichi Uchio, Department of ...
Fujita H, Ueno T, Suzuki S, Harada K, Tsukahara-Kawamura T, Ozaki H, Uchio E   +6 more
doaj  

The Duality of Subtyping.

, 2020
Subtyping is a concept frequently encountered in many programming languages and calculi. Various forms of subtyping exist for different type system features, including intersection types, union types or bounded quantification. Normally these features are designed independently of each other, without exploiting obvious similarities (or dualities ...
Oliveira, Bruno C. d. S., Shaobo, Cui, Rehman, Baber   +2 more
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Expanded Indications of Molecular-Targeted Drugs in Perioperative Therapy of Breast Cancer

Tokyo Women's Medical University Journal
In recent years, numerous molecular-targeted drugs have become available for the perioperative therapy of breast cancer, bringing about a revolution in breast cancer treatment.
Eiichiro Noguchi, Sadako Akashi-Tanaka
doaj   +1 more source