Results 71 to 80 of about 1,160,550 (308)

Integrated subtype reproducibility and number of subtype-discriminant features.

, 2012
Integrated subtype reproducibility and number of subtype-discriminant features.
Qianxing Mo (169134), Chris Sander (1345), Jason Huse (169143), Venkatraman E. Seshan (169139), Adam B. Olshen (169141), Nikolaus Schultz (169137), Marc Ladanyi (4470), Ronglai Shen (86479)   +7 more
core   +1 more source

MRI subtype DATA.xlsx

, 2022
MRI data on ethnicity and ...
nazimah ab mumin (4425115)
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Prevalence and transmission of HIV-1 drug resistance mutations among patients with treatment failure and newly diagnosed people in Liangshan Prefecture, China, in 2021–2023

Frontiers in Public Health
IntroductionDespite expanded antiretroviral therapy (ART) in China, HIV transmission persists. Liangshan Prefecture is one of the areas in China most severely affected by HIV, with high levels of drug resistance.
Rong Pei, Rong Pei, Yulian Zhang, Chunnong Jike, Gang Yu, Ling Su, Ju Wang, Lin Xiao, Yubing Wang, Maogang Shen, Jiayi Liao, Yifei Zheng, Joris Hemelaar   +12 more
doaj   +1 more source

Single‐Cell RNA‐seq Reveals a Developmental Hierarchy Super‐Imposed Over Subclonal Evolution in the Cellular Ecosystem of Prostate Cancer

Advanced Science, 2022
Prostate cancer (PCa) is a complex disease. An ongoing accumulation of mutations results in increased genetic diversity, with the tumor acquiring distinct subclones. However, non‐genetic intra‐tumoral heterogeneity, the cellular differentiation state and
Guangzhe Ge, Yang Han, Jianye Zhang, Xinxin Li, Xiaodan Liu, Yanqing Gong, Zhentao Lei, Jie Wang, Weijie Zhu, Yangyang Xu, Yiji Peng, Jianhua Deng, Bao Zhang, Xuesong Li, Liqun Zhou, Huiying He, Weimin Ci   +16 more
doaj   +1 more source

Comparative analysis of spatial and transform domain methods for meningioma subtype classification [PDF]

, 2010
Pattern recognition in histopathological image analysis requires new techniques and methods. Various techniques have been presented and some state of the art techniques have been applied to complex textural data in histological images.
Qureshi, Hammad A., Rajpoot, Nasir M. (Nasir Mahmood)   +1 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Swine influenza A virus subtype H1N2 in Sweden [PDF]

, 2014
The influenza A virus subtypes H1N1, H1N2 and H3N2 are prevalent in pig populations worldwide. All scientific data point towards swine as the key host species for new human influenza pandemics, which have been suggested to evolve in pigs from viral genes
Metreveli, Giorgi
core   +1 more source

Studying luminal A and B subtypes of breast cancer under paracrine secretion of fibro- blasts [PDF]

BioImpacts
Introduction: Understanding the key role of the tumor microenvironment in specifying molecular markers of breast cancer subtypes is of a high importance in diagnosis and treatment. Therefore, the possibility of interconversion of luminal states and their
Nazila Jalilzadeh, Neda Barzgar Barough, Mehrdad Karami, Amir Baghbanzadeh, Kobra Velaei   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source