Results 51 to 60 of about 1,350,829 (302)

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Identification of efferocytosis-related subtypes in gliomas and elucidating their characteristics and clinical significance

Frontiers in Cell and Developmental Biology, 2023
Introduction: Gliomas, the most prevalent tumors of the central nervous system, are known for their aggressive nature and poor prognosis. The heterogeneity among gliomas leads to varying responses to the same treatments, even among similar glioma types ...
Mengge Gao, Jinsheng Huang, Bo Yang, Qiong Liu, Miaoqing Luo, Biying Yang, Xujia Li, Xiaofang Liu   +7 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

A Database of Lung Cancer-Related Genes for the Identification of Subtype-Specific Prognostic Biomarkers

Biology, 2023
The molecular subtype is critical for accurate treatment and follow-up in patients with lung cancer; however, information regarding subtype-associated genes is dispersed among thousands of published studies.
Yining Liu, Min Zhao, Hong Qu
doaj   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

The Light Chain Defines the Duration of Action of Botulinum Toxin Serotype A Subtypes

mBio, 2018
Botulinum neurotoxin (BoNT) is the causative agent of botulism and a widely used pharmaceutical to treat a variety of neurological diseases. BoNTs are 150-kDa protein toxins organized into heavy chain (HC) and light chain (LC) domains linked by a ...
Sabine Pellett, Marite Bradshaw, William H. Tepp, Christina L. Pier, Regina C. M. Whitemarsh, Chen Chen, Joseph T. Barbieri, Eric A. Johnson   +7 more
doaj   +1 more source

Can non-small cell lung cancer histologic subtypes predict survival? A single institution experience [PDF]

, 2018
Introduction. The latest histological classification of lung adenocarcinoma includes lepidic, acinar, papillary, micropapillary, and solid as subtypes.
Cristian, Balalau, Cristian, Iaciu, Hainarosie, Razvan, Nitipir, Cornelia, Olaru, Mihaela, Orlov, Cristina, Pantea Stoian, Anca, Popa, Ana-Maria, Slavu, Iulian   +8 more
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

THE PREVALENCE OF HUMAN IMMUNODEFIENCY VIRUS-1 (HIV-1) SUBTYPES AND TRANSMISSION METHOD AMONG HIV/AIDS INFECTION PATIENT IN TULUNGAGUNG, EAST JAVA INDONESIA

Indonesian Journal of Tropical and Infectious Disease, 2015
The rapid epidemic growth of HIV is continuing in Indonesia. There are some factors which have influenced the spreading of this epidemic in Indonesia, such as the poor awareness to avoid unsafe free sex attitude and the sharing of needles and syringes ...
Achmad Ardianto, Siti Qamariyah Khairunisa, Tomohiro Kotaki, Adiana Mutamsari Witaningrum, M. Qushay, Juniastuti Juniastuti, Retno Pudji Rahayu, Prihartini Widiyanti, Budi Utomo, Maria Inge Lusida, Nasronudin Nasronudin   +10 more
doaj   +1 more source

Dysfunction of the Auditory Brainstem as a Neurophysiology Subtype of Autism Spectrum Disorder

Frontiers in Neuroscience, 2021
Autism spectrum disorder (ASD) is very heterogeneous, particularly in language. Studies have suggested that language impairment is linked to auditory-brainstem dysfunction in ASD.
Jierong Chen, Zhen Wei, Chun Liang, Binguang Liu, Jimin Guo, Xuejun Kong, Minshi Huang, Ziwen Peng, Guobin Wan   +8 more
doaj   +1 more source