Results 121 to 130 of about 1,067,207 (315)
Integrated subtype reproducibility and number of subtype-discriminant features.
Integrated subtype reproducibility and number of subtype-discriminant features.
Qianxing Mo (169134) +7 more
core +1 more source
The changing molecular epidemiology of HIV-1 in Liangshan prefecture, China, in 2021–2023
IntroductionLiangshan Prefecture is one of the areas in China most severely affected by human immunodeficiency virus (HIV), but little is known about the molecular epidemiology of HIV-1 in this area.
Rong Pei +13 more
doaj +1 more source
Vif is required for HIV-1 replication in natural target cells by counteracting host restriction factors, APOBEC3 (A3) proteins. We recently demonstrated that Vif expression level can be changed by naturally occurring single-nucleotide variations within ...
Naoya Doi +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Includes bibliographical references (leaves 114-128).In this study I explored the possibility of making HIV-1 subtype C Pr55gag-based chimaeric virus-like particles (VLPs) as a boost to the HIV-IC multigene DNA vaccine pTHr.grttnC, which encodes a ...
Halsey, Richard James
core
Subtype satisfiability and entailment [PDF]
Subtype constraints were introduced in advanced programming language research for designing subtype systems and program analysis algorithms. Two logical problems arise in this context: subtype satisfiability and subtype entailment. Subtype satisfiability
Priesnitz, Tim
core +1 more source
Purpose: To evaluate the optical quality and tear-film dynamics in patients with aqueous-deficient or evaporative subtype of dry eye disease (DED). Methods: Twenty-five aqueous-deficient dry eye (ADDE) patients, 25 DED patients with meibomian gland ...
Fen Ye +6 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Scatter plots of FC of subtype C amplicons recombined in subtype B and subtype C backbones.
(A–D) X-axis: Subtype B and Y-axis: subtype C for 1346 pairs; Black line x = y; (A) all drug classes (R2 = 0.88); (B) NRTIs (R2 = 0.88); (C) NNRTIs (R2 = 0.90); (D) PIs (R2 = 0.87); (E) Analysis of the pair-wise comparison of differences in FCs per clone
David Nauwelaers (350953) +10 more
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source

