Results 141 to 150 of about 1,160,550 (308)

Data-Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Milella G, Vacchiano V, Velucci V, Zoccolella S, Liguori R, Defazio G.   +5 more
europepmc   +2 more sources

Module configuration in each subtype.

, 2019
Module configuration in each subtype.
Ru Chen (186859), Hiroshi Seno (567264), Aiko Sugiyama (5626496), Masahiro Sugimoto (65573)   +3 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Patient demographics by histological subtype.

, 2014
Patient demographics by histological subtype.
Michelle Dixon (531817), Aiste McCormick (531812), Rachel L. O′Donnell (531811), Madeleine Moat (531815), Angelika Kaufman (531818), Nicola J. Curtin (351064), Anna Grundy (531816), Asima Mukhopadhyay (531813), San Soohoo (531819), Laura C. Woodhouse (531814), Ahmed Elattar (531820), Richard J. Edmondson (531821)   +11 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Has avian influenza virus H9 originated from a bat source?

Frontiers in Veterinary Science
Influenza A viruses are important pathogens that can cause diseases with high mortality in humans, animals, and birds; and wild birds are considered the primary reservoir of all subtypes in nature.
Kobey Karamendin, Aidyn Kydyrmanov, Sasan Fereidouni   +2 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Cross-ethnic subtype spread.

, 2015
Number of individuals diagnosed each year demonstrating cross ethnic spread of HIV, including subtype A or B in Ethiopian born, subtype A or C in Israeli-born, and subtype B or C in FSU immigrants. Et, Ethiopia; FSU, Former Soviet Union; Is, Israel.
Eduardo Shahar (384539), Diana Averbuch (384545), Yonat Shemer Avni (786472), Klaris Riesenberg (384538), Dan Turner (240679), Eynat Kedem (786470), Sara Radian Sade (786473), Valery Istomin (384547), Shirley Girshengorn (786471), Itzchak Levy (364292), Frank Maldarelli (69272), Zipi Kra-Oz (515359), Zehava Grossman (7882), Hila Elinav (515355), Ilan Asher (396203), Zev Sthoeger (384542), Karen Olstein-Pops (515352), Boaz Avidor (384536), Zohar Mor (378648), Wei Shao (182165), Michal Chowers (384546), Shlomo Maayan (384543), Margalit Lorber (786468), Daniel Elbirt (384541), Bat Sheva Gottesman (786469)   +24 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

HIV-1 subtype C sequences.

, 2012
HIV-1 subtype C sequences.
Gonzalo Bello (138839), Edson Oliveira Delatorre (146835)   +1 more
core   +1 more source