Results 121 to 130 of about 14,250,657 (303)

Patients characteristics according to subtype of infection (B or non-B).

, 2015
* n(%)** median (IQR)MSM: men-who-have-sex-with-menIDU: injective drug userPatients characteristics according to subtype of infection (B or non-B).
Marta Parera (749144), María Ángeles Marcos (749147), Laura Zamora (232408), Christian Manzardo (341791), David Nicolas (749143), José María Miró (749148), José María Gatell (5653063), María López-Diéguez (749145), Juan Ambrosioni (749142), Anabel Romero (749146), Tomás Pumarola (178995), Fernando Agüero (276046), Omar Sued (132831), Manuel Gómez-Carrillo (5652313)   +13 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Neutralization potential of plasma antibodies from HIV-1 patients against subtype-B and C tier 2 viruses.

, 2012
The cross neutralizing activities of plasma antibodies from 80 HIV-1 infected drug naïve individuals from north India against the tier 2 subtype-B and C viruses indicated on the top of the table.
Kalpana Luthra (138056), Raiees Andrabi (138046), Naveet Wig (56509), Rajesh Kumar (72124), Manju Bala (138050), Anjali Hazarika (138055)   +5 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

A: Distribution of unique intra-subtype recombinant variants in subject 168 infected with HIV-1 subtype A1.

, 2013
The number of unique recombinant variants was 20 (53%). The enriched recombinant variants were represented by 2, 7 and 10 copies. B: Distribution of unique intra-subtype recombinant variants in subject 107 infected with HIV-1 subtype A1.
Rachel Manongi (124361), Vladimir Novitsky (124352), Noel Sam (124363), M. Essex (124372), Jeannie Baca (124358), Ireen E. Kiwelu (124350), Mary F. McLane (124367), Lauren Margolin (124355), John Shao (124364), Saidi H. Kapiga (124370)   +9 more
core   +1 more source

Drivers of HIV-1 transmission: The Portuguese case.

PLoS ONE, 2019
BACKGROUND:Portugal has one of the most severe HIV-1 epidemics in Western Europe. Two subtypes circulate in parallel since the beginning of the epidemic.
Andrea-Clemencia Pineda-Peña, Marta Pingarilho, Guangdi Li, Bram Vrancken, Pieter Libin, Perpétua Gomes, Ricardo Jorge Camacho, Kristof Theys, Ana Barroso Abecasis, Portuguese HIV-1 Resistance Study Group   +9 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Read numbers and subtype frequencies.

, 2014
a) Undetermined in regard of sample.b) Undetermined in regard of subtype.nd = not done.na = not applicable.Read numbers and subtype frequencies.
Enkelejda Miho (654050), Sai T. Reddy (167874), Alexandra Trkola (51210), Thomas Liechti (654049), Osvaldo Zagordi (304585), Huldrych F. Günthard (173082), Merle Schanz (173073), Michael Huber (274369)   +7 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Production of monoclonal antibody to subtype 9 of Neisseria meningitidis and the distribution of this subtype in Brazil

Brazilian Journal of Infectious Diseases
A new monoclonal antibody (5F81A4P1.9), which is specific for subtype 9 antigen of meningococci, was studied. The antibodies were raised against a previously non-typable (NT) serogroup B strain from Brazilian patients and were found to react with the ...
Elza F.T. Belo, Ligia M.C.C. Coutinho, Aline S. Ferraz, Elizabeth N. De Gaspari   +3 more
doaj   +1 more source