Results 101 to 110 of about 14,250,657 (303)

An association between K65R and HIV-1 subtype C viruses in patients treated with multiple NRTIs. [PDF]

, 2017
Objectives: HIV-1 subtype C might have a greater propensity to develop K65R mutations in patients with virological failure compared with other subtypes. However, the strong association between viral subtype and confounding factors such as exposure groups
Mark Nelson, Collins, S, Smit, Erasmus, Tostevin, Anna, Ellen White, Hongyi Zhang, Sophie Jose, Zhang, Hongyi, Erasmus Smit, Churchill, D, Dunn, DT, Pillay, Deenan, Jose, Sophie, Winston, Alan, Sabin, Caroline, Dunn, David T, Duncan Clark, Caroline Sabin, David T. Dunn, Nelson, M, Clark, Duncan, Churchill, Duncan, White, E, Winston, A, Sabin, C, Pillay, D, Collins, Simon, Smit, E, Tostevin, A, UK HIV Drug Resistance Database and the UK Collaborative HIV Cohort, Clark, D, Jose, S, Alan Winston, Anna Tostevin, null null, Simon Collins, Dunn, David T., Deenan Pillay, Zhang, H, White, Ellen, Nelson, Mark, Duncan Churchill   +41 more
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Hepatitis B Virus, Genotypes and Subtypes

, 2022
Hepatitis simply means inflammation of liver. This word came from heap: the Latin for liver and “titis” means inflammation. In addition to viruses, many varieties of agents can cause hepatitis such as bacteria, parasites, fungi and chemical agents including drugs, toxins and alcohol.
openaire   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Proportional B cell and T cell subtype changes in MS patients during fingolimod treatment.

, 2014
(A) CD19+ B cell subtype proportion and (B) CD4+ T cell subtype proportion within the PB of treatment-naive, IFN-β and fingolimod-treated MS patients. Results are presented as relative values within the CD19+ B cell or CD4+ T cell population.
Piet Stinissen (136034), Judith Fraussen (652504), Raymond Hupperts (235385), Bart Van Wijmeersch (652506), Tessa Dhaeze (652503), Nele Claes (652502), Bieke Broux (652505), Niels Hellings (136039), Veerle Somers (652507)   +8 more
core   +1 more source

AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity [PDF]

, 2007
Neuronal nAChRs are a diverse family of pentameric ion channels with wide distribution throughout cells of the nervous and immune systems. However, the role of specific subtypes in normal and pathological states remains poorly understood due to the lack ...
Sixma, Titia K., Alewood, Paul F., Buettner, Regina, van Elk, R, Smit, A.B., Sixma, T., Dutertre, S., Nicke, A, van Elk, R., Smit, A., Nicke, Annette, Alewood, P. F., Sixma, T.K., Kendel, Y., Smit, AB, Lewis, R. J., Hopping, G., Kendel, Y, Büttner, Regina, Elk, René van, Ulens, C, Ulens, Chris, Buttner, R, Kendel, Yvonne, Sixma, TK, Fish, Alexander, Lewis, R.J., Schroeder, Christina, Lewis, Richard,, Smit, August,, Alewood, P.F., Lewis, Richard J., Fish, A, Sixma, Titia,, Schroeder, C., Alewood, Paul,, Fish, A., Alewood, P., Dutertre, Sébastien, Smit, August B., Ulens, C., Hopping, Gene, Nicke, A., Lewis, R., Ulens, Chris (author), Schroeder, Christina (author), Dutertre, Sébastien (author), Lewis, Richard J. (author), Lewis, Richard, J, Büttner, Regina (author), van Elk, René (author), Alewood, Paul, F, Fish, Alexander (author), Nicke, Annette (author), Sixma, Titia, K, Kendel, Yvonne (author), Hopping, Gene (author), Alewood, Paul F. (author), Sixma, Titia K. (author), Smit, August, B, Smit, August B. (author), Büttner, R., van Elk, Rene   +62 more
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Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Cell subtype discrimination.

, 2013
A and B denote correspondence analysis to classify subtypes of cells. A, the subtype of female and male iPSCs. B, the subtype of fetal and adult SCs. C and D show the accuracy of discriminating subtypes of cells.
Ying Du (42066), Chunxiao Zhou (281730), Anyou Wang (281729), Qianchuan He (143345)   +3 more
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Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Neutralization susceptibility of B subtype variant B" primary HIV-1 isolates. The HEC/FIOCRUZ AIDS Clinical Research Group.

, 1998
AIDS & Molecular Immunology Laboratory. Department of Immunology. Rio de Janeiro, RJ, BrasilAIDS & Molecular Immunology Laboratory. Department of Immunology. Rio de Janeiro, RJ, BrasilAIDS & Molecular Immunology Laboratory. Department of Immunology.
Bongertz, Vera, Castro Filho, Bernardo Galvão, The HEC/FIOCRUZ Aids Clinical Research Group, João Filho, Esaú Custódio, Morgado, Mariza Gonçalves, Grinsztejn, Beatriz, Costa, Catia Ines, Guimarães, Monick Lindenmeyer   +7 more
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