Results 31 to 40 of about 14,250,657 (303)

Nucleic acid template and the risk of a PCR-Induced HIV-1 drug resistance mutation. [PDF]

PLoS ONE, 2010
The HIV-1 nucleoside RT inhibitor (NRTI)-resistance mutation, K65R confers intermediate to high-level resistance to the NRTIs abacavir, didanosine, emtricitabine, lamivudine, and tenofovir; and low-level resistance to stavudine. Several lines of evidence
Vici Varghese, Elijah Wang, Farbod Babrzadeh, Michael H Bachmann, Rajin Shahriar, Tommy Liu, Svetlana Jean M Mappala, Baback Gharizadeh, W Jeffrey Fessel, David Katzenstein, Seble Kassaye, Robert W Shafer   +11 more
doaj   +1 more source

Molecular Modeling of Subtype-Specific Tat Protein Signatures to Predict Tat-TAR Interactions That May Be Involved in HIV-Associated Neurocognitive Disorders

Frontiers in Microbiology, 2022
HIV-1 is responsible for a spectrum of neurocognitive deficits defined as HIV-associated neurocognitive disorders (HAND). The HIV transactivator of transcription (Tat) protein plays a key role in the neuropathophysiology of HAND.
Monray E. Williams, Ruben Cloete
doaj   +1 more source

Subtypes and phylogenetic analysis of human immunodeficiency virus-1 in Jayapura

Universa Medicina, 2015
BACKGROUND Human immunodeficiency virus (HIV) is a retrovirus that infects human immune system. HIV is genetically differentiated into HIV-1 and HIV-2. HIV- 1 is classified into 3 groups : M,N and O.
Mirna Widiyanti, Tri Wibawa, Holy Arif Wibowo   +2 more
doaj   +1 more source

Molecular epidemiology and HIV-1 variant evolution in Poland between 2015 and 2019

Scientific Reports, 2021
The occurrence of HIV-1 subtypes differs worldwide and within Europe, with non-B variants mainly found across different exposure groups. In this study, we investigated the distribution and temporal trends in HIV-1 subtype variability across Poland ...
Karol Serwin, Anna Urbańska, Kaja Scheibe, Magdalena Witak-Jędra, Maria Jankowska, Maria Hlebowicz, Monika Bociąga-Jasik, Anna Kalinowska-Nowak, Martyna Biała, Hubert Ciepłucha, Władysław Łojewski, Anita Olczak, Elżbieta Jabłonowska, Aldona Kowalczuk-Kot, Błażej Rozpłochowski, Adam Witor, Miłosz Parczewski   +16 more
doaj   +1 more source

The features of Tat protein of human immunodeficiency virus type 1 (Retroviridae: Lentivirus: Lentivirus humimdef1) non-A6 variants, characteristic for the Russian Federation

Вопросы вирусологии
Introduction. Tat protein is a trans-activator of HIV-1 genome transcription, with additional functions including the ability to induce the chronic inflammatory process. Natural amino acid polymorphisms in Tat may affect its functional properties and the
Anna I. Kuznetsova, Anastasiia A. Antonova, Aleksey V. Lebedev, Ekaterina N. Ozhmegova, Anastasia V. Shlykova, Ilya A. Lapovok, Oxana V. Galzitskaya   +6 more
doaj   +1 more source

The muscarinic receptor subtype in mouse pancreatic B‐cells [PDF]

FEBS Letters, 1988
Isolated mouse islets were used to identify the muscarinic receptor subtype present in pancreatic B‐cells. We thus compared the inhibitory potencies of atropine (non‐specific), of pirenzepine (specific for M1 receptors) and of compound AF‐DX 116 (specific for cardiac M2 receptors) on acetylcholine‐induced insulin release, 86Rb+ efflux and 45Ca2+ efflux.
Henquin, Jean-Claude, Nenquin, Myriam
openaire   +2 more sources

Molecular analysis of the new allele 803delC of subtype B

Zhongguo shuxue zazhi
Objective To analyze the serological characteristics and molecular mechanism of a novel B subtype allele 803delC. Methods ABO blood group was detected by serological method.
Liping WANG, Xiaomei YU, Shujie LI, Xi LI, Baojun JI, Xinju LI, Futing SUN   +6 more
doaj   +1 more source

Nef HIV-1 (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus-1), multifunctional protein: features of genetic virus variants circulating in Russia

Вопросы вирусологии
Introduction. Nef provides high level of HIV-1 replication due to synergy of its multiple functions and is an important factor in the pathogenesis of HIV infection. Nef is considered as a target for development of therapeutic agents.
Anna I. Kuznetsova, Anastasiia A. Antonova, Larisa A. Protasova, Anna V. Glyakina, Kristina V. Kim, Iana M. Munchak, Ekaterina N. Mezhenskaya, Elena A. Orlova-Morozova, Alexander Yu. Pronin, Alexey G. Prilipov, Oxana V. Galzitskaya   +10 more
doaj   +1 more source

B-cell non-Hodgkin lymphoma (B-NHL) subtype distribution by population.

, 2017
B-cell non-Hodgkin lymphoma (B-NHL) subtype distribution by population.
Ronit Nirel (3746140), Arnon Nagler (144514), Asad Ramlawi (495391), Areej Khatib (3746128), Rania Abu Seir (3746122), Fouad Sabatin (3746131), Gail Amir (205062), Dina Ben Yehuda (3746119), Paolo Boffetta (63968), Meirav Kedmi (373381), Ziad Abdeen (359438), Eldad J. Dann (3746137), Ora Paltiel (102457), Martin Ellis (3746125), Geffen Kleinstern (2600173), Husein Elyan (3746134), Riki Perlman (587949)   +16 more
core   +1 more source

Subtype-specific expression derived from clustering

, 2022
This file contains subtype-specific expression derived from NMF clustering results. 
Jarrett Eshima (13813720)
core   +1 more source