Results 41 to 50 of about 14,250,657 (303)

Differential drug resistance acquisition in HIV-1 of subtypes B and C. [PDF]

PLoS ONE, 2007
BACKGROUND: Subtype C is the most prevalent HIV-1 subtype in the world, mainly in countries with the highest HIV prevalence. However, few studies have evaluated the impact of antiretroviral therapy on this subtype.
Esmeralda A J M Soares, André F A Santos, Thatiana M Sousa, Eduardo Sprinz, Ana M B Martinez, Jussara Silveira, Amilcar Tanuri, Marcelo A Soares   +7 more
doaj   +1 more source

Neisseria meningitidis Subtype Nomenclature

Clinical Diagnostic Laboratory Immunology, 1999
We believe the novel subtyping nomenclature proposed for Neisseria meningitidis ([7][1]) is flawed and, if adopted, will create chaos for meningococcal epidemiology with serious implications for public health monitoring and vaccine development.
M C, Maiden, J, Russell, J, Suker, I M, Feavers   +3 more
openaire   +2 more sources

Neutralization Susceptibility of B Subtype Variant B′′ Primary HIV‐1 Isolates

, 1998
The HEC/FIOCRUZ Aids Clinical Research Groupp: V. G. V. SANTOS, V. C. Rolla, S. Cavalcante, M. C. G. Galhardo and M. R. C. Guimarães.Susceptibility to autologous and heterologous neutralization of primary human immunodeficiency virus (HIV)-1 isolates ...
Bongertz, Vera, Castro Filho, Bernardo Galvão, João Filho, Esaú Custódio, Morgado, Mariza Gonçalves, Grinsztejn, Beatriz, Costa, Catia Ines, Guimarães, Monick Lindenmeyer, Galvão‐Castro, Grinsztejn, Bongertz, João Filho, Guimarães, Costa, Morgado, The Hec/fiocruz Aids Clinical Research Group   +14 more
core   +1 more source

Phylodynamic profile of HIV-1 subtype B, CRF01_AE and the recently emerging CRF51_01B among men who have sex with men (MSM) in Singapore. [PDF]

PLoS ONE, 2013
HIV-1 subtype B and CRF01_AE are the predominant infecting subtypes among men who have sex with men (MSM) in Singapore. The genetic history, population dynamics and pattern of transmission networks of these genotypes remain largely unknown. We delineated
Kim Tien Ng, Kah Ying Ng, Wei Xin Khong, Kuan Kiat Chew, Palvinder Kaur Singh, Joe Kwan Yap, Mei Ting Tan, Yee Sin Leo, Oliver Laeyendecker, Thomas C Quinn, Adeeba Kamarulzaman, Kok Keng Tee, Oon Tek Ng   +12 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Scatter plots of FC of subtype C amplicons recombined in subtype B and subtype C backbones.

, 2013
(A–D) X-axis: Subtype B and Y-axis: subtype C for 1346 pairs; Black line x = y; (A) all drug classes (R2 = 0.88); (B) NRTIs (R2 = 0.88); (C) NNRTIs (R2 = 0.90); (D) PIs (R2 = 0.87); (E) Analysis of the pair-wise comparison of differences in FCs per clone
David Nauwelaers (350953), Bart Winters (350954), Kurt Van Baelen (350955), Lieven J. Stuyver (249761), Rachelle Bonesteel (350959), Ellen Chi (350956), Derek Steiner (350958), Margriet Van Houtte (326880), Mimi Zhou (350957), Kim Steegen (326871), Colin Aston (350960)   +10 more
core   +1 more source

HIV-1 subtype B: Traces of a pandemic

Virology, 2016
Human migration is a major process that shaped the origin and dissemination of HIV. Within HIV-1, subtype B (HIV-1B) is the most disseminated variant and it is assumed to be the causative agent in approximately 11% of all cases of HIV worldwide. Phylogenetic studies have revealed that HIV-1B emerged in Kinshasa (Africa) and was introduced into the ...
Dennis Maletich, Junqueira, Sabrina Esteves de Matos, Almeida   +1 more
openaire   +2 more sources

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

HIV-1 subtype B sequences.

, 2014
HIV-1 subtype B sequences.
Yaxelis Mendoza (508647), Juan Castillo Mewa (508648), Claudia González (44831), Gonzalo Bello (138839), Blas Armién (372981), Santiago Avila-Ríos (3219234), Gustavo Reyes-Terán (115886), Alexander A. Martínez (508649), Claudia García-Morales (196309), Juan M. Pascale (179353)   +9 more
core   +1 more source

Genetic and immunological characterization of new subtype G envelope expressing HIV-1 pseudoviruses [PDF]

, 2014
Includes bibliographical references.One of the greatest challenges for the development of an effective HIV-1 vaccine is the high genetic diversity of this pathogen and the complex escape mechanisms employed by the envelope gp120 and gp41 glycoprotein ...
Essomba, Rene Ghislain
core   +1 more source