Results 61 to 70 of about 14,250,657 (303)

Discrimination of Subtype B and Non-Subtype B Strains of Human Immunodeficiency Virus Type 1 by Serotyping: Correlation with Genotyping [PDF]

Journal of Clinical Microbiology, 1999
ABSTRACT The ability of a peptide-based serotyping assay to differentiate human immunodeficiency virus (HIV) type 1 (HIV-1) subtype B infections from non-subtype B infections was investigated with 166 anti-HIV-1- and HIV RNA-positive (by PCR) serum or plasma specimens.
G, Murphy, F J, Belda, C P, Pau, J P, Clewley, J V, Parry   +4 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Increased HIV Subtype Diversity Reflecting Demographic Changes in the HIV Epidemic in New South Wales, Australia

Viruses, 2020
Changes over time in HIV-1 subtype diversity within a population reflect changes in factors influencing the development of local epidemics. Here we report on the genetic diversity of 2364 reverse transcriptase sequences from people living with HIV-1 in ...
Francesca Di Giallonardo, Angie N. Pinto, Phillip Keen, Ansari Shaik, Alex Carrera, Hanan Salem, Christine Selvey, Steven J. Nigro, Neil Fraser, Karen Price, Joanne Holden, Frederick J. Lee, Dominic E. Dwyer, Benjamin R. Bavinton, Andrew E. Grulich, Anthony D. Kelleher, on behalf of the NSW HIV Prevention Partnership Project   +16 more
doaj   +1 more source

The HIV‐1 Non‐subtype B Workgroup: An International Collaboration for the Collection and Analysis of HIV‐1 Non‐subtype B Data [PDF]

Journal of the International AIDS Society, 2005
HIV-1 group M, the major pathogen responsible for the AIDS pandemic, is characterized by a wide range of genetic diversity among distinct subtypes (A-K), sub-subtypes (A1, A2; F1, F2), and circulating recombinant forms (CRF01_AE, CRF02_AG, and more).
Kantor, Rami, Shafer, Robert W, Katzenstein, David   +2 more
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Comparison of the epidemiology, profile of mutations, and clinical response to antiretrovirals among subtypes B and F of the human immunodeficiency virus type 1

Memorias do Instituto Oswaldo Cruz, 2007
The authors compared demographic aspects and profile of mutations in 80 patients with subtypes B and F of human immunodeficiency type 1 (HIV-1). Genotyping of the pol region of the reverse transcriptase was performed using the ViroSeqTM Genotyping System.
Heloisa Ramos Lacerda, Luzidalva Barbosa de Medeiros, Ana Maria Salustiano Cavalcanti, Ricardo Arraes de Alencar Ximenes, Maria de Fátima Pessoa Militão de Albuquerque   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Avian metapneumovirus subtype B vaccination in commercial broiler chicks: heterologous protection and selected host transcription responses to subtype A or B challenge

, 2022
Avian metapneumovirus (aMPV) causes respiratory disease and drops in egg production in chickens, and is routinely controlled by vaccination. However, the host’s immune response to virulent challenge in vaccinated or unvaccinated broiler chickens is ...
Ball, Christopher, Herrmann, Andreas, Ganapathy, Kannan, Manswr, Basim, Lemiere, Stephane, Basim Manswr, Andreas Herrmann, Kannan Ganapathy, Stephane Lemiere, Christopher Ball   +9 more
core   +1 more source

Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C

Retrovirology, 2010
Background HIV-1 subtype C infections account for over half of global HIV infections, yet the vast focus of HIV-1 research has been on subtype B viruses which represent less than 12% of the global pandemic.
Moisi Daniella, Oliveira Maureen, Asahchop Eugene, Quan Yudong, Xu Hong-Tao, Wainberg Mark A   +5 more
doaj   +1 more source

Diversity of HIV-1 subtype B: implications to the origin of BF recombinants. [PDF]

PLoS ONE, 2010
BackgroundThe HIV-1 subtype B epidemic in Brazil is peculiar because of the high frequency of isolates having the GWGR tetramer at V3 loop region. It has been suggested that GWGR is a distinct variant and less pathogenic than other subtype B isolates ...
Elcio Leal, Fabiola E Villanova
doaj   +1 more source