Results 61 to 70 of about 560,921 (309)

Purity Independent Subtyping of Tumors (PurIST), a clinically robust, single sample classifier for tumor subtyping in pancreatic cancer

open access: yesClinical Cancer Research, 2019
Purpose: Molecular subtyping for pancreatic cancer has made substantial progress in recent years, facilitating the optimization of existing therapeutic approaches to improve clinical outcomes in pancreatic cancer.
N. Rashid   +18 more
semanticscholar   +1 more source

Subtyping and Parametricity [PDF]

open access: yes, 2003
In this paper we study the interaction of subtyping and parametricity. We describe a logic for a programming language with parametric polymorphism and subtyping. The logic supports the formal definition and use of relational parametricity.
Abadi, Martin   +2 more
core  

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

Robust Prognostic Subtyping of Muscle-Invasive Bladder Cancer Revealed by Deep Learning-Based Multi-Omics Data Integration

open access: yesFrontiers in Oncology, 2021
Muscle-invasive bladder cancer (MIBC) is the most common urinary system carcinoma associated with poor outcomes. It is necessary to develop a robust classification system for prognostic prediction of MIBC.
Xiaolong Zhang   +10 more
doaj   +1 more source

CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models

open access: yesScientific Reports, 2017
Colorectal cancers (CRCs) can be divided into four gene expression-based biologically distinct consensus molecular subtypes (CMS). This classification provides a potential framework for stratified treatment, but to identify novel CMS-drug associations ...
P. Eide, J. Bruun, R. Lothe, A. Sveen
semanticscholar   +1 more source

Comparison of subtyping methods for neuroimaging studies in Alzheimer’s disease: a call for harmonization

open access: yesBrain Communications, 2020
Biological subtypes in Alzheimer’s disease, originally identified on neuropathological data, have been translated to in vivo biomarkers such as structural magnetic resonance imaging and positron emission tomography, to disentangle the heterogeneity ...
R. Mohanty   +9 more
semanticscholar   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak   +9 more
wiley   +1 more source

Behavioural Subtyping in Process Algebra

open access: yes, 2020
Subtyping relations embody a notion of substitutability, and are an important tool in formal methods. The downward simulation relation is well-known and widely used as a subtyping and refinement relation for state-based approaches, but there is no single
Briscoe-Smith, C.
core   +1 more source

First-order theory of subtyping constraints [PDF]

open access: yes, 2002
We investigate the first-order theory of subtyping constraints. We show that the first-order theory of non-structural subtyping is undecidable, and we show that in the case where all constructors are either unary or nullary, the first-order theory ...
Priesnitz, Tim   +5 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

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