Results 81 to 90 of about 560,921 (309)

Host-specific Cryptosporidium, Giardia and Enterocytozoon bieneusi in shelter dogs from central Europe

Parasitology
Cryptosporidium spp., Giardia intestinalis and microsporidia are unicellular opportunistic pathogens that can cause gastrointestinal infections in both animals and humans. Since companion animals may serve as a source of infection, the aim of the present
Magdalena Szydłowicz, Żaneta Zajączkowska, Antonina Lewicka, Błażej Łukianowski, Mateusz Kamiński, Nikola Holubová, Bohumil Sak, Martin Kváč, Marta Kicia   +8 more
doaj   +1 more source

Molecular subtyping of colorectal cancer: recent progress, new challenges and emerging opportunities

Seminars in Cancer Biology, 2018
Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Similar to many other malignancies, CRC is a heterogeneous disease, making it a clinical challenge for optimization of treatment modalities in reducing the morbidity
Wei Wang, R. Kandimalla, Hao Huang, Li-Na Zhu, Ying Li, F. Gao, A. Goel, Xin Wang   +7 more
semanticscholar   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Molecular identification and subtyping of Cryptosporidium spp. in laboratory mice and rats

Parasite
Cryptosporidium species can infect humans and more than 260 animal species, including 54 rodent species. However, data on the occurrence and genetic characterizations of Cryptosporidium spp. in laboratory rodents are limited.
Zhou Shanshan, Hu Xinyu, Li He, Yuan Zhongying, Li Zhen, Liu Aiqin, Jiang Yanyan, Cao Jianping   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Flu seasons during the period 2018-2023 in Sarajevo Canton, Bosnia and Herzegovina: possible impact of the SARS-CoV-2 pandemic on the influenza A and B virus circulation

Medicinski Glasnik
Aim During the pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many countries reported a significant decrease in the prevalence of influenza virus cases.
Almedina Moro, Amela Dedeić Ljubović, Edina Zahirović, Selma Mutevelić, Suzana Arapčić, Goran Čerkez, Irma Salimović-Bešić   +6 more
doaj   +1 more source

Semantic Subtyping for Objects and Classes [PDF]

, 2012
We propose an integration of structural subtyping with boolean connectives and semantic subtyping to define a Java-like programming language that exploits the benefits of both techniques.
Gorla, Daniele, Varacca, Daniele, Dardha, Ornela, Daniele Varacca, Daniele Gorla, Ornela Dardha   +5 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Early detection and population dynamics of Listeria monocytogenes in naturally contaminated drains from a meat processing plant

Frontiers in Microbiology
Listeria monocytogenes, a significant foodborne pathogen, often contaminates ready-to-eat foods through cross-contamination in food processing environments, and floor drains represent one of the most common sites of persistence.
Annette Fagerlund, Trond Møretrø, Merete Rusås Jensen, Solveig Langsrud, Birgitte Moen   +4 more
doaj   +1 more source

Prevalence and subtype distribution of Blastocystis in ethnic minority groups on both sides of the China–Myanmar border, and assessment of risk factors

Parasite, 2019
Blastocystis is one of the most common intestinal parasites in humans worldwide. To understand its prevalence and to explore the risk factors for Blastocystis in humans in developing countries, a molecular epidemiological investigation of Blastocystis ...
Gong Baiyan, Liu Xiaohua, Wu Yanchen, Xu Ning, Xu Meng, Yang Fengkun, Tong Lei, Zhou Kexin, Cao Jianping, Liu Aiqin, Shen Yujuan   +10 more
doaj   +1 more source