Results 101 to 110 of about 1,747,151 (350)

Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection

open access: yesScientific Reports, 2017
Dengue is considered as a major health issue which causes a number of deaths worldwide each year; tropical countries are majorly affected by dengue outbreaks.
Mudassar Ali   +5 more
semanticscholar   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

open access: yesAdvanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer   +17 more
wiley   +1 more source

Exploring Leishmania secretory proteins to design B and T cell multi-epitope subunit vaccine using immunoinformatics approach

open access: yesScientific Reports, 2017
Visceral leishmaniasis (VL) is a fatal form of leishmaniasis which affects 70 countries, worldwide. Increasing drug resistance, HIV co-infection, and poor health system require operative vaccination strategy to control the VL transmission dynamics ...
N. Khatoon, R. Pandey, V. Prajapati
semanticscholar   +1 more source

Recombinant bacterial lipoproteins as vaccine candidates

open access: yes, 2015
[[abstract]]Recombinant bacterial lipoproteins (RLP) with built-in immuno-stimulating properties for novel subunit vaccine development are reviewed.
Leng, CH;Liu, SJ;Chen, HW;Chong, P
core   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang   +11 more
wiley   +1 more source

Single dose of recombinant baculovirus vaccine expressing sigma B and sigma C genes provides good protection against novel duck reovirus challenge in ducks

open access: yesPoultry Science
The novel duck reovirus (NDRV) disease causes high economic losses, resulting in substantial economic losses in waterfowl industry. However, currently, no commercial vaccines are available to alleviate NDRV infection throughout the world.
Yufei Wang   +9 more
doaj   +1 more source

Nanoparticles in influenza subunit vaccine development: Immunogenicity enhancement

open access: yesInfluenza and Other Respiratory Viruses, 2019
The threat of novel influenza infections has sparked research efforts to develop subunit vaccines that can induce a more broadly protective immunity by targeting selected regions of the virus.
Atin Khalaj-Hedayati   +3 more
semanticscholar   +1 more source

Expression of cholera toxin B subunit in Saccharomyces cerevisiae [PDF]

open access: yes
Cholera toxin, secreted by Vibrio cholerae, consists of A and B subunits. Cholera toxin B subunit (CTB) is used in many scientific research. It has already been expressed in several bacterial and plant systems.
ارزنلو, محسن   +6 more
core  

Varicella Breakthrough Infection and Vaccine Effectiveness in Taiwan

open access: yes, 2012
We performed this nationwide retrospective investigation among the recipients of varicella vaccine to evaluate the breakthrough varicella infection rate, factors associated with breakthrough infection and the vaccine effectiveness.
HUANG, WEN-CHAN;HUANG, LI-MIN;CHANG, I-SHOU;TSAI, FANG-YU;CHANG, LUAN-YIN   +1 more
core   +1 more source

Preliminary Study on the Efficacy of a Recombinant, Subunit SARS-CoV-2 Animal Vaccine against Virulent SARS-CoV-2 Challenge in Cats

open access: yes, 2023
The objective of this work was to evaluate the safety and efficacy of a recombinant, subunit SARS-CoV-2 animal vaccine in cats against virulent SARS-CoV-2 challenge.
Jason Millership   +24 more
core   +1 more source

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