Results 131 to 140 of about 1,747,151 (350)

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Safety of the recombinant cholera toxin B subunit, killed whole-cell (rBS-WC) oral cholera vaccine in pregnancy [PDF]

, 2012
INTRODUCTION: Mass vaccinations are a main strategy in the deployment of oral cholera vaccines. Campaigns avoid giving vaccine to pregnant women because of the absence of safety data of the killed whole-cell oral cholera (rBS-WC) vaccine.
Jin Kyung Park (78612), Jacqueline L. Deen (148731), Mohammad Ali, Abdul A. Saleh, Saleh, A. A., Na Yoon Chang (148714), Rita Reyburn (130140), Stephen Obaro (148749), Sunheang Shin (148734), Anna Lena Lopez, Sack, D., Kamala Thriemer, Said M. Ali, Ramadhan Hashim (148699), Ahmed M. Khatib (130136), David Sack, Lorenz von Seidlein, Anna Lena Lopez (92298), Aguado, M. T., Raymond Hutubessy (130149), Godwin Enwere, Shaame, A. J., Ahmed M. Khatib, Maria Teresa Aguado (148740), Godwin Enwere (148705), Abdul A. Saleh (148759), Attiye J Shaame, Raymond Hutubessy, John D. Clemens, Park, J. K., Jacqueline L. Deen, Sunheang Shin, Said M Ali, Abdul A Saleh, Attiye J. Shaame, Mohammad Ali (73095), Jiddawi, M. S., Maria Teresa Aguado, Na Yoon Chang, Rita Reyburn, Lena Lopez, Schaetti, C., John D. Clemens (148728), Attiye J. Shaame (148753), Marie Paule Kieny, Khatib, A. M., Reyburn, R., Ley, B., Shin, S., Lopez, A. L., Mohamed S. Jiddawi (148765), Deok Ryun Kim, Stephen Obaro, Thriemer, K., Ahmed M Khatib, Jacqueline L Deen, Clemens, J. D., Kieny, M. P., Mohamed S Jiddawi, Ali, S. M., Hashim, R., John D Clemens, David Sack (148746), Enwere, G., Chang, N. Y., Deok Ryun Kim (78610), Ramadhan Hashim, Benedikt Ley, Mohamed S. Jiddawi, Ali, M., Deen, J. L., Benedikt Ley (148722), von Seidlein, L., Hutubessy, R., Christian Schaetti (130127), Kim, D. R., Christian Schaetti, Lorenz von Seidlein (45473), Kamala Thriemer (148725), Obaro, S., Marie Paule Kieny (148743), Said M. Ali (130132), Jin Kyung Park   +82 more
core   +2 more sources

Precision-engineering of subunit vaccine particles for prevention of infectious diseases

, 2023
Vaccines remain the best approach for the prevention of infectious diseases. Protein subunit vaccines are safe compared to live-attenuated whole cell vaccines but often show reduced immunogenicity.
Chen, Shuxiong, Pounraj, Saranya, Sivakumaran, Nivethika, Rehm, Bernd HA, Kakkanat, Anjali, Kabir, Md Tanvir, Sam, Gayathri   +6 more
core   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Research progress on sequential immunization strategies of COVID-19 vaccines: a review

Zhongguo gonggong weisheng
The global pandemic of the coronavirus disease 2019 (COVID-19) has had a serious impact on global life safety and economic development. Vaccination with the coronavirus disease vaccine (COVID-19 vaccine) is an important measure to prevent infection ...
Rongrong DAI, Hangjie ZHANG, Jianmin JIANG   +2 more
doaj   +1 more source

Heterogeneity in malaria exposure and vaccine response: implications for the interpretation of vaccine efficacy trials. [PDF]

, 2010
BACKGROUND: Phase III trials of the malaria vaccine, RTS, S, are now underway across multiple sites of varying transmission intensity in Africa. Heterogeneity in exposure, vaccine response and waning of efficacy may bias estimates of vaccine efficacy ...
Michael T White, Jamie T Griffin, Azra C Ghani, Drakeley, Chris J, Ghani Azra C, Ghani, Azra C, Griffin, Jamie T, Drakeley Chris J, White, Michael T, White Michael T, Griffin Jamie T, Chris J Drakeley   +11 more
core   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Current strategies, advances, and challenges in multi-epitope subunit vaccine development for African swine fever virus

Veterinary Integrative Sciences
African Swine Fever (ASF), a highly contagious and lethal viral disease affecting swine populations, presents a critical global threat with no approved vaccine.
Ella Mae Joy S. Sira, Edward C. Banico, Lauren Emily Fajardo, Nyzar Mabeth O. Odchimar, Alea Maurice Simbulan, Fredmoore L. Orosco   +5 more
doaj   +1 more source

Enhancing enterovirus A71 vaccine production yield by microcarrier profusion bioreactor culture

, 2017
[[abstract]]Hand, foot and mouth diseases (HFMD) are mainly caused by Enterovirus A71 (EV-A71) infections. Clinical trials in Asia conducted with formalin-inactivated EV-A71 vaccine candidates produced from serum-free Vero cell culture using either ...
Liu, CC;Wu, SC;Wu, SR;Lin, HY;Guo, MS;Hu, AYC;Chow, YH;Chiang, JR;Shieh, DB;Chong, P
core   +1 more source