Results 141 to 150 of about 83,566 (244)

CD25 modulation enhances broadly neutralizing antibody response of SARS-CoV-2 subunit vaccine. [PDF]

Commun Biol
Li F, Yu X, Zhang C, Liu W, Tian H, Wang X, Wang P, Yu B, Yu X.   +8 more
europepmc   +1 more source

Impact of delayed blood donation sample processing and testing on SARS‐CoV‐2 serological assay results in an evolving pandemic response

Transfusion, EarlyView.
Abstract Background The two largest US blood collection organizations led a multiphased, multicenter nationwide SARS‐CoV‐2 blood donor‐based serosurveillance program. The potential impact of delayed sample processing and prolonged refrigerated or frozen storage on anti‐SARS‐CoV‐2 antibody detection was investigated.
Marion C. Lanteri, Valerie Green, Hasan Sulaeman, Mars Stone, James Haynes, Clara Di Germanio, Sakina Smith, Patricia G. Villaflor, Jamel Groves, Phillip C. Williamson, Susan L. Stramer, Melissa M. Coughlin, Jefferson M. Jones, Eduard Grebe, Michael P. Busch, Paula Saa   +15 more
wiley   +1 more source

AntiPan: a genome-informed in silico pipeline for advancing subunit vaccine discovery against Staphylococcus aureus. [PDF]

Sci Rep
Ibrahim MS, Fahmy JA, Helal MA, Hakim FT, Sidarous LR, Attallah NE, Abouelhadid S, Elhadidy M, Badr E.   +8 more
europepmc   +1 more source

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

The Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu, Asish Dasgupta, Jaskaran Singh Hora, Kuang‐Hueih Chen, Arinjay Banerjee, Stephen L. Archer   +5 more
wiley   +1 more source

A porcine circovirus type 2d-based virus-like particle subunit vaccine effectively protects pigs against homologous challenge. [PDF]

Front Microbiol
Chen P, Sun Y, Wang M, Li C, Xia Y, Liu H, Qi L, Si F, Miao D.   +8 more
europepmc   +1 more source

Decoding the Black Box of Fish Vaccines Efficacy in Basic and Applied Contexts

Reviews in Aquaculture, Volume 18, Issue 4, September 2026.
ABSTRACT Vaccines are the frontline defense in aquaculture, yet predicting their real‐world performance remains a tricky puzzle. Unlike terrestrial veterinary vaccines, fish vaccines largely operate through “Black Box” processes, where we observe the outcomes but rarely understand the underlying immune mechanisms. Laboratory trials, though informative,
Jiří Kyslík, Mikolaj Adamek, Tomáš Korytář   +2 more
wiley   +1 more source

Understanding the Molecular Landscape of Alopecia Areata: Key Genes, Regulatory Networks, and Therapeutic Targets

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Introduction Alopecia areata (AA) is an autoimmune disorder characterized by hair loss due to immune‐mediated destruction of hair follicles. The polygenic nature of AA, influenced by genetic and environmental factors, complicates its pathogenesis.
Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Saleh Salem Bahaj, Ghada Farouk Mohammed, Lina Mohammed Atef   +4 more
wiley   +1 more source

UNICOR-v, a Pan-Coronavirus Subunit Vaccine, Demonstrates Immunogenicity and Efficacy Against MERS-CoV Infection. [PDF]

Vaccines (Basel)
Cole ME, Jossi S, Dillen C, Fanaroff R, Frieman M, Pleguezuelos O.   +5 more
europepmc   +1 more source

Using generalized quantitative structure–property relationship (QSPR) models to predict host cell protein retention in ion‐exchange chromatography

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 7, Page 1420-1428, July 2026.
Abstract BACKGROUND Selecting an optimal chromatography resin during biopharmaceutical downstream process development is a great challenge. This is especially the case for recombinant subunit vaccines, where product properties vary greatly and recovery often involves cell lysis, which yields a complex mixture of different host cell materials. Host cell
Tim Neijenhuis, Olivier Le Bussy, Geoffroy Geldhof, Marieke E Klijn, Marcel Ottens   +4 more
wiley   +1 more source

Immunogenicity and Protective Effects of an Ag85B Tuberculosis Subunit Vaccine Formulated with Synthetic TLR4 Agonists in BCG-Boosted Mice. [PDF]

Vaccines (Basel)
Kim SM, Yun JS, Shin E, Lee J, Kim YJ, Jeong HS, Jung YW, Kim D.   +7 more
europepmc   +1 more source