Results 251 to 260 of about 1,122,864 (370)

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Assessment of the Adjuvant Effects of Lentinan on the Tuberculosis Subunit Vaccine BG. [PDF]

Vaccines (Basel)
Zhou S, Hou Y, Zhang X, Lv Z, Hu Q, Yang X, Niu H.   +6 more
europepmc   +1 more source

Mechanopharmacology of cellular microenvironment stiffness: Therapeutic strategies for age‐related diseases

British Journal of Pharmacology, Volume 183, Issue 4, Page 945-956, February 2026.
Ageing brings about various biochemical, structural and mechanical alterations within tissues, profoundly impacting cellular behaviour and function. One of the hallmark changes observed with ageing is an increase in cellular microenvironment stiffness, a biomechanical property influenced by intrinsic factors within the cell and extrinsic factors from ...
Wang HaiYang, Cheong Dorothy Hui Juan, Lee Zhao‐Yong, Tran Thai   +3 more
wiley   +1 more source

Second Boost of Omicron SARS-CoV-2 S1 Subunit Vaccine Induced Broad Humoral Immune Responses in Elderly Mice [PDF]

Eun Kim, Muhammad S. Khan, Alessandro Ferrari, Shaohua Huang, Thomas W. Kenniston, Irene Cassaniti, Fausto Baldanti, Andrea Gambotto   +7 more
openalex   +1 more source

Structure-Guided Engineering of Protein VP2 from Epizootic Hemorrhagic Disease Virus Maximizes Production and Confers Complete Protection as Subunit Vaccine. [PDF]

Vaccines (Basel)
Jurado S, Jiménez-Cabello L, Nuñez MDC, Utrilla-Trigo S, Calvo-Pinilla E, Mazuecos-Aragonés I, Gutierrez JR, Falcón A, Ortego J, Escribano JM.   +9 more
europepmc   +1 more source

Isolation and Characterisation of Serotype III in Miamiensis avidus (Ciliophora: Scuticociliatida) From Olive Flounder (Paralichthys olivaceus)

Journal of Fish Diseases, Volume 49, Issue 2, February 2026.
ABSTRACT Miamiensis avidus (Ciliophora: Scuticociliatida, syn. Philasterides dicentrarchi) is a significant pathogen causing scuticociliatosis in olive flounder (Paralichthys olivaceus) in Korea and Japan. In this study, the BB19 strain, isolated from olive flounder, was identified as M.
Jin‐Young Kim, Jeong‐Hoon Kim, Su‐Mi Shin, Taeho Kim, Se Ryun Kwon, Sung‐Ju Jung   +5 more
wiley   +1 more source

Augmenting Subunit-Vaccine-Induced Immunity through a Dual Strategy of Gold Nanoparticle Conjugation and Chitosan Microneedle-Mediated Sustained Delivery. [PDF]

ACS Appl Mater Interfaces
Lin ZY, Chen YL, Wu CL, Chen YH, Chen MC.   +4 more
europepmc   +1 more source

Cortisol Regulates PD‐1 and IL‐12 in Canine Leishmaniasis

Parasite Immunology, Volume 48, Issue 2, February 2026.
ABSTRACT Canine visceral leishmaniasis (CanL) is a tropical zoonosis caused by Brazil's protozoan Leishmania (L.) infantum. Disorders in the hypothalamic–pituitary–adrenal (HPA) axis have been reported in human and experimental visceral leishmaniasis, but not yet in canine leishmaniasis.
Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Mayla Abbas Guimarães, Bianca Maciel Marques de Souza, Sofia Furrier Soares, Luiz Eduardo Amador Loiola Pereira, Valéria Marçal Felix de Lima   +6 more
wiley   +1 more source

Evaluation of a Respiratory Syncytial Virus Subunit Vaccine Candidate in IgA-Deficient Mice: Insights into the Role of IgA in Vaccine-Induced Immunity and Protection. [PDF]

Vaccines (Basel)
Gonzalez Gonzalez L, Zhiani M, Witt J, van Drunen Littel-van den Hurk S.   +3 more
europepmc   +1 more source

Development and evaluation of two subunit vaccine candidates containing antigens of hepatitis E virus, rotavirus, and astrovirus [PDF]

, 2016
Ming Xia, Chao Wei, Leyi Wang, Dianjun Cao, Xiang‐Jin Meng, Xi Jiang, Ming Tan   +6 more
openalex   +1 more source