Results 151 to 160 of about 471,587 (292)

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Enabling global access to potent subunit vaccines with a simple and scalable injectable hydrogel platform. [PDF]

Biomater Sci
Ganesh P, Prossnitz AN, Jons CK, Eckman N, Alakesh A, Song YE, Sen S, Appel EA.   +7 more
europepmc   +1 more source

Ginseng Polysaccharide Enhances the Humoral and Cellular Immune Responses to SARS-CoV-2 RBD Protein Subunit Vaccines. [PDF]

Vaccines (Basel), 2023
Zhang J, Feng J, Huang Y, Zhou B, Li B, Zhang R.   +5 more
europepmc   +1 more source

Signs of Cross‐Reactivity Between SARS‐CoV‐2 and Other Coronaviruses in a Pre‐Vaccine Swedish School Setting

Acta Paediatrica, EarlyView.
ABSTRACT Aim This pilot study explored signs of immunological cross‐reactivity between SARS‐CoV‐2 and human coronaviruses (HCoVs) in a Swedish school setting. Methods A cross‐sectional, hypothesis‐generating study was conducted late 2020 before vaccines against COVID‐19 were available.
Lina Schollin Ask, Sharon Kühlmann Berenzon, Ulrika Marking, Sara Nouiser, Andreas Bråve, Sören Andersson, Charlotta Nordenhäll, Tobias Alfvén, Teghesti Tecleab, Olof Hertting, Tyler Sandberg, Wanda Christ, Jonas Klingström, Kim Blom, Charlotta Nilsson   +14 more
wiley   +1 more source

Multi-attribute monitoring (MAM) methodology for glycosylated subunit vaccines. [PDF]

Sci Rep
Shajahan A, Jenkins LM, Barefoot N, Maldonado D, Wolff JJ, Yang Y, Kueltzo LA, Ficca V, Scheideman E, Loukinov I, Carruthers C, Benmohamed D, Gowetski DB, Jiang R, Yang SR, Carlton K, Gall JG, Lei QP.   +17 more
europepmc   +1 more source

An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines. [PDF]

Prog Biophys Mol Biol, 2023
Bayani F, Hashkavaei NS, Arjmand S, Rezaei S, Uskoković V, Alijanianzadeh M, Uversky VN, Ranaei Siadat SO, Mozaffari-Jovin S, Sefidbakht Y.   +9 more
europepmc   +1 more source

Immunogenicity and Protective Efficacy of Five Vaccines Against Highly Pathogenic Avian Influenza Virus H5N1, Clade 2.3.4.4b, in Fattening Geese

Background/Objectives: The risk of the introduction of highly pathogenic avian influenza virus (HPAIV) in geese breeding and fattening flocks is heightened due to the necessity of free-range access to grazing grounds.
Heike Hufen, Martin Beer, Leticia Frizzo da Silva, Christian Grund, Ronja Piesche, Christophe Cazaban, Luis Ramírez-Martínez, Timm Harder   +7 more
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Cooperative supramolecular integration of QS-21 into polymeric micelles as a tunable nanoadjuvant platform for subunit vaccines. [PDF]

RSC Adv
Márquez PG, Alonso LG, Marfía JI, Smith I, Mourelle AC, Formica ML, Miranda MV, Valdez SN, Wolman FJ, Glisoni RJ.   +9 more
europepmc   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source