Results 151 to 160 of about 79,320 (275)

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Potential of Cationic Liposomes as Adjuvants/Delivery Systems for Tuberculosis Subunit Vaccines

The weakness of the BCG vaccine and its highly variable protective efficacy in controlling tuberculosis (TB) in different age groups as well as in different geographic areas has led to intense efforts towards the development and design of novel vaccines.
طاهری, رمضانعلی, فرنوش, غلامرضا, ممتازی بروجنی, امیر عباس, خادمی, فرزاد, جانسون, توماس, صاحبکار, امیر حسین   +5 more
core   +1 more source

Intraspecific Variation in the Characteristics of Cryptocaryon irritans Isolated in Japan

Journal of Fish Diseases, EarlyView.
ABSTRACT Cryptocaryon irritans is an obligate parasitic ciliate and the causative agent of cryptocaryoniasis. This parasite is widely distributed in tropical and subtropical marine waters, and numerous outbreaks in aquaculture have been reported worldwide. Previous studies have documented variations in biological traits, such as cell size, serotype and
Hiromi Matsuoka, Toshihide Iwatsuki, Maho Kotake, Tomoki Honryo, Sho Shirakashi, Naoki Itoh, Yuho Watanabe   +6 more
wiley   +1 more source

Development of a Novel Polyleucine-Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus. [PDF]

Small
Lu L, Cruz JLG, Giri R, Zhang Y, Bashiri S, Cadena LCD, Li S, Khalil ZG, Hussein WM, Wang J, Kiong J, Lu X, Zhang J, Lu M, Huang W, Kong WY, Nahar UJ, Koirala P, Guo Z, Walden P, Blumenthal A, Begun J, Alexandrov K, Toth I, Stephenson RJ, Skwarczynski M.   +25 more
europepmc   +1 more source

Ginseng Polysaccharide Enhances the Humoral and Cellular Immune Responses to SARS-CoV-2 RBD Protein Subunit Vaccines. [PDF]

Vaccines (Basel), 2023
Zhang J, Feng J, Huang Y, Zhou B, Li B, Zhang R.   +5 more
europepmc   +1 more source

Efficacy Assessment of Montanide GEL 02 PR and Liposome‐Based Encapsulation as Adjuvants for an FrpA Subunit Vaccine Against Photobacteriosis in Solea senegalensis

Journal of Fish Diseases, EarlyView.
ABSTRACT Photobacteriosis is a major threat to marine aquaculture, and the siderophore transporter FrpA represents a promising target for effective subunit vaccine development. In this study, we evaluated Montanide GEL 02 PR and phosphatidylcholine‐based liposomes as aqueous and safer alternatives to Freund's adjuvant for an FrpA‐based subunit vaccine ...
Marta A. Lages, Miguel Balado, Abel M. Forero, Lucía Ageitos, Jaime Rodríguez, Carlos Jiménez, Manuel L. Lemos, Beatriz Magariños   +7 more
wiley   +1 more source

Enabling global access to potent subunit vaccines with a simple and scalable injectable hydrogel platform. [PDF]

Biomater Sci
Ganesh P, Prossnitz AN, Jons CK, Eckman N, Alakesh A, Song YE, Sen S, Appel EA.   +7 more
europepmc   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

Journal of Fish Diseases, EarlyView.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun, Muhammed Duman, Jesús L. Romalde, Nihed Ajmi, Gorkem Tasci, Cuneyt Ozakin, Nazmiye Ulku Tuzemen, Bekir Akça, Sebahattin Ergün, Sevdan Yılmaz, Izzet Burcin Saticioglu   +10 more
wiley   +1 more source

Multi-attribute monitoring (MAM) methodology for glycosylated subunit vaccines. [PDF]

Sci Rep
Shajahan A, Jenkins LM, Barefoot N, Maldonado D, Wolff JJ, Yang Y, Kueltzo LA, Ficca V, Scheideman E, Loukinov I, Carruthers C, Benmohamed D, Gowetski DB, Jiang R, Yang SR, Carlton K, Gall JG, Lei QP.   +17 more
europepmc   +1 more source

An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines. [PDF]

Prog Biophys Mol Biol, 2023
Bayani F, Hashkavaei NS, Arjmand S, Rezaei S, Uskoković V, Alijanianzadeh M, Uversky VN, Ranaei Siadat SO, Mozaffari-Jovin S, Sefidbakht Y.   +9 more
europepmc   +1 more source