Subunit vaccines with a saponin-based adjuvant boost humoral and cellular immunity to MERS coronavirus. [PDF]
Chang CC +17 more
europepmc +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Design of B-Cell Multi-Epitope Subunit Vaccines Against <i>Glaesserella parasuis</i> by Reverse Vaccinology: An In Silico and In Vivo Study. [PDF]
Gong Y +9 more
europepmc +1 more source
Abstract Background The two largest US blood collection organizations led a multiphased, multicenter nationwide SARS‐CoV‐2 blood donor‐based serosurveillance program. The potential impact of delayed sample processing and prolonged refrigerated or frozen storage on anti‐SARS‐CoV‐2 antibody detection was investigated.
Marion C. Lanteri +15 more
wiley +1 more source
Rational design of respiratory syncytial virus dimeric F-subunit vaccines in protein and mRNA forms. [PDF]
Li J +22 more
europepmc +1 more source
A Comprehensive Review of the Protein Subunit Vaccines Against COVID-19. [PDF]
Heidary M +7 more
europepmc +1 more source
SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu +5 more
wiley +1 more source
The combination of inactivated and subunit vaccines enhances protective efficacy against Mycoplasma synoviae. [PDF]
Yi C +9 more
europepmc +1 more source
Mucosal Adjuvants Delivered by a Mucoadhesive Patch for Sublingual Administration of Subunit Vaccines. [PDF]
Monge C +5 more
europepmc +1 more source
Decoding the Black Box of Fish Vaccines Efficacy in Basic and Applied Contexts
ABSTRACT Vaccines are the frontline defense in aquaculture, yet predicting their real‐world performance remains a tricky puzzle. Unlike terrestrial veterinary vaccines, fish vaccines largely operate through “Black Box” processes, where we observe the outcomes but rarely understand the underlying immune mechanisms. Laboratory trials, though informative,
Jiří Kyslík +2 more
wiley +1 more source

