Results 191 to 200 of about 79,320 (275)

Immunogenicity of monovalent and multivalent subunit vaccines against SARS-CoV-2 variants in mice with divergent vaccination history. [PDF]

Microbiol Spectr
Wang R, Lyu Y, Chen M, Sun L, Zhou S, Cui Y, Ma J, Kong D, Lu J, Li X, Xie L.   +10 more
europepmc   +1 more source

Author Correction: Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge. [PDF]

Sci Rep, 2023
Liu Y, Ye L, Lin F, Gomaa Y, Flyer D, Carrion R, Patterson JL, Prausnitz MR, Smith G, Glenn G, Wu H, Compans RW, Yang C.   +12 more
europepmc   +1 more source

Understanding the Molecular Landscape of Alopecia Areata: Key Genes, Regulatory Networks, and Therapeutic Targets

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Introduction Alopecia areata (AA) is an autoimmune disorder characterized by hair loss due to immune‐mediated destruction of hair follicles. The polygenic nature of AA, influenced by genetic and environmental factors, complicates its pathogenesis.
Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Saleh Salem Bahaj, Ghada Farouk Mohammed, Lina Mohammed Atef   +4 more
wiley   +1 more source

Harnessing computational immunology to design targeted subunit vaccines for infectious bursal disease in poultry. [PDF]

Front Bioinform
Oladipo EK, Adeyemo SF, Oshoneye AI, Akintola HB, Elegbede BI, Ayoomoba TU, Atilade DA, Adegboye OO, Ejikeme AE, Balogun CO, Aderibigbe KA, Popoola PO, Alabi VA, Irewolede BA, Ano-Edward GH, Ayeleso AO, Onyeaka H.   +16 more
europepmc   +1 more source

Using generalized quantitative structure–property relationship (QSPR) models to predict host cell protein retention in ion‐exchange chromatography

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 7, Page 1420-1428, July 2026.
Abstract BACKGROUND Selecting an optimal chromatography resin during biopharmaceutical downstream process development is a great challenge. This is especially the case for recombinant subunit vaccines, where product properties vary greatly and recovery often involves cell lysis, which yields a complex mixture of different host cell materials. Host cell
Tim Neijenhuis, Olivier Le Bussy, Geoffroy Geldhof, Marieke E Klijn, Marcel Ottens   +4 more
wiley   +1 more source

Immune Dysregulation in Branched Chain Organic Acidemias

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Organic acidemias (OAs) are a group of inherited disorders, most commonly caused by defects in mitochondrial enzymes involved in amino acid and fatty acid metabolism. While they characteristically present with metabolic and neurological crises, growing evidence reveals a significant burden of chronic immune dysregulation in some disorders and ...
Abdul L. Shakerdi, Jack Drda, Justin A. Dutta, Jerry Vockley   +3 more
wiley   +1 more source

JAK Inhibition in PNPT1‐Related Mitochondrial Interferonopathy: A Case Report and Review of Mitochondrial–Immune Crosstalk

JIMD Reports, Volume 67, Issue 4, July 2026.
ABSTRACT Biallelic pathogenic variants in PNPT1 cause combined oxidative phosphorylation deficiency 13 (COXPD13) (MIM #614932), linking mitochondrial dysfunction to type I interferon (IFN) activation through cytosolic leakage of mitochondrial double‐stranded RNA (mt‐dsRNA).
Dan Ross Brooks, Hyun Yong Koh, Taylor Martin Kerrins, Steven Lang, Emily Bland, Rui Yang, Sarah Kogan Nicholas, Stephanie Jean Sikkink, Stephen Kralik, Christine Eng, Chaya Nautiyal Murali, Seema Lalani, Pilar Lenglet Magoulas, Lisa Emrick, Kristen Sydney Fisher, Fernando Scaglia   +15 more
wiley   +1 more source

Multivalent S2 subunit vaccines provide broad protection against Clade 1 sarbecoviruses in female mice. [PDF]

Nat Commun
Halfmann PJ, Patel RS, Loeffler K, Yasuhara A, Van De Velde LA, Yang JE, Chervin J, Troxell C, Huang M, Zheng N, Wright ER, Thomas PG, Wilson PC, Kawaoka Y, Kane RS.   +14 more
europepmc   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Microfluidic-Chip-Based Formulation and In Vivo Evaluations of Squalene Oil Emulsion Adjuvants for Subunit Vaccines. [PDF]

Vaccines (Basel)
Bhangde S, Fresnay-Murray S, Garretson T, Ashraf A, O'Hagan DT, Amiji MM, Lodaya RN.   +6 more
europepmc   +1 more source