Results 11 to 20 of about 79,320 (275)

Advancements in the development of subunit influenza vaccines [PDF]

Microbes and Infection, 2015
The ongoing threat of influenza epidemics and pandemics has emphasized the importance of developing safe and effective vaccines against infections from divergent influenza viruses. In this review, we first introduce the structure and life cycle of influenza A viruses, describing major influenza A virus-caused pandemics.
Naru Zhang, Bo-Jian Zheng, Lu Lu
exaly   +5 more sources

A platform technology for generating subunit vaccines against diverse viral pathogens [PDF]

Frontiers in Immunology, 2022
The COVID-19 pandemic response has shown how vaccine platform technologies can be used to rapidly and effectively counteract a novel emerging infectious disease.
Andrew Young, Andrew Young, Ariel Isaacs, Connor A. P. Scott, Naphak Modhiran, Naphak Modhiran, Christopher L. D. McMillan, Stacey T. M. Cheung, Jennifer Barr, Glenn Marsh, Nazia Thakur, Nazia Thakur, Dalan Bailey, Kenneth S. M. Li, Hayes K. H. Luk, Kin-Hang Kok, Susanna K. P. Lau, Patrick C. Y. Woo, Wakako Furuyama, Andrea Marzi, Paul R. Young, Paul R. Young, Paul R. Young, Keith J. Chappell, Keith J. Chappell, Keith J. Chappell, Daniel Watterson, Daniel Watterson, Daniel Watterson   +28 more
doaj   +2 more sources

Prospective randomized open-label comparative study of immunogenicity after subunit and polymeric subunit influenza vaccines administration among mothers and infants

Human Vaccines & Immunotherapeutics, 2018
Pregnant women are risk group for influenza infection. Results of new subunit vaccines application have not been studied enough. Prospective, randomized, open-label comparative study of subunit (Agrippal) and polymeric subunit (Grippol plus) vaccines. 42
Mikhail Petrovich Kostinov, Alexander Petrovich Cherdantsev, Alexei Isaevich Kuselman, Nelli Kimovna Akhmatova, Aristitsa Mikhailovna Kostinova, Elena Viktorovna Deryabina, Evgeniia Olegovna Demina, Anton Mikhailovich Kostinov   +7 more
doaj   +2 more sources

Subunit Vaccines Against Emerging Pathogenic Human Coronaviruses

Frontiers in Microbiology, 2020
Seven coronaviruses (CoVs) have been isolated from humans so far. Among them, three emerging pathogenic CoVs, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and a newly ...
Ning Wang, Jian Shang, Shibo Jiang, Shibo Jiang, Lanying Du   +4 more
doaj   +2 more sources

Research Progress on Varicella-Zoster Virus Vaccines

Vaccines
Varicella-zoster virus (VZV) poses significant public health challenges as the etiological agent of varicella (chickenpox) and herpes zoster (HZ), given its high transmissibility and potential for severe complications.
Hongjing Liu, Lingyan Cui, Sibo Zhang, Hong Wang, Wenhui Xue, Hai Li, Yuyun Zhang, Lin Chen, Ying Gu, Tingting Li, Ningshao Xia, Shaowei Li   +11 more
doaj   +2 more sources

Inactivated and subunit vaccines to prevent shigellosis

Expert Review of Vaccines, 2009
Shigellosis remains a formidable disease globally, with children of the developing world bearing the greatest number of infections. The need for an affordable, safe and efficacious vaccine has persisted for decades. Vaccines to prevent shigellosis can be divided into living and nonliving approaches.
Robert W Kaminski, Edwin V Oaks
exaly   +3 more sources

Adjuvant Selection for Influenza and RSV Prefusion Subunit Vaccines [PDF]

, 2021
Subunit vaccines exhibit favorable safety and immunogenicity profiles and can be designed to mimic native antigen structures. However, pairing with an appropriate adjuvant is imperative in order to elicit effective humoral and cellular immune responses ...
Naphak Modhiran, Chappell, K.J., Danushka K. Wijesundara, Christopher L. D. McMillan, Young, P.R., Watterson, D., Paul R. Young, Li, Z., Isaacs, A., Modhiran, N., Zheyi Li, Daniel Watterson, Stacey T. M. Cheung, Charani Ranasinghe, Ranasinghe, C., Ariel Isaacs, McMillan, C.L.D., Keith J. Chappell, Cheung, S.T.M., Wijesundara, D.K.   +19 more
core   +2 more sources

Advanced subunit vaccine delivery technologies: From vaccine cascade obstacles to design strategies

Acta Pharmaceutica Sinica B, 2023
Designing and manufacturing safe and effective vaccines is a crucial challenge for human health worldwide. Research on adjuvant-based subunit vaccines is increasingly being explored to meet clinical needs.
Yingying Hou, Min Chen, Yuan Bian, Xi Zheng, Rongsheng Tong, Xun Sun   +5 more
doaj   +1 more source

Trimeric, APC-Targeted Subunit Vaccines Protect Mice against Seasonal and Pandemic Influenza [PDF]

Journal of Virology, 2023
Bjarne Bogen, Tor KRISTIAN Andersen, Gunnveig Grødeland   +2 more
exaly   +2 more sources

Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development

EBioMedicine, 2020
Background: Coronaviruses pose a serious threat to global health as evidenced by Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and COVID-19.
Eun Kim, Geza Erdos, Shaohua Huang, Thomas W. Kenniston, Stephen C. Balmert, Cara Donahue Carey, V. Stalin Raj, Michael W. Epperly, William B. Klimstra, Bart L. Haagmans, Emrullah Korkmaz, Louis D. Falo, Jr., Andrea Gambotto   +12 more
doaj   +1 more source