Results 231 to 240 of about 471,587 (292)

The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo, Li Li, Fang Wang, Wen Liu, Yan Zhang   +4 more
wiley   +1 more source

From Undifferentiated Connective Tissue Disease to Common Variable Immunodeficiency: A Novel NFKB1 Mutation in a Pediatric Case

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Common variable immunodeficiency (CVID) may initially manifest as undifferentiated connective tissue disease (UCTD) in the absence of recurrent infections or hypogammaglobulinemia. In patients presenting with warning signs, neither older age nor normal immunoglobulin levels should preclude consideration of CVID; early genetic testing is ...
Yu‐Jie Hu, Sheng Hao, Dan Feng, Bing‐Xue Huang, Wen‐Yan Huang   +4 more
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, Volume 58, Issue 5, Page 1396-1412, September 2026.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

From injection to inhalation: A STING‐activating mucosal adjuvant reprograms vaccination

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Weijie Wang, Muzhuo Wang, Lu Lu, Shibo Jiang, Zezhong Liu   +4 more
wiley   +1 more source

Anti-Flavivirus Vaccines: Review of the Present Situation and Perspectives of Subunit Vaccines Produced in Escherichia coli

Vaccines, 2020
This article aims to review the present status of anti-flavivirus subunit vaccines, both those at the experimental stage and those already available for clinical use.
Sérgio Carneiro Araujo, Viviane Maimoni Gonçalves, Robert Andreata-Santos   +2 more
exaly   +2 more sources

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Rotavirus subunit vaccines

1996
We evaluated rotavirus subunit vaccines for use in humans and animals. Insect cells were co-infected with combinations of individual baculovirus recombinants expressing human, bovine or simian rotavirus VP2, VP4, VP6 or VP7 to produce virus-like particles (VLPs).
Conner, M.E., Crawford, S.E., Barone, C., O'Neal, C., Zhou, Y.J., Fernandez, F., Parwani, A., Saif, L.J., Cohen, J., Estes, M.K.   +9 more
openaire   +3 more sources

Modern Subunit Vaccines: Development, Components, and Research Opportunities

ChemMedChem, 2013
Traditional vaccines, based on the administration of killed or attenuated microorganisms, have proven to be among the most effective methods for disease prevention.
István Tóth, Peter Moyle
exaly   +2 more sources

Protein subunit vaccines: Promising frontiers against COVID-19

Journal of Controlled Release
The emergence of COVID-19 has posed an unprecedented global health crisis, challenging the healthcare systems worldwide. Amidst the rapid development of several vaccine formulations, protein subunit vaccines have emerged as a promising approach.
Vasso Apostolopoulos, Vandana Patravale, Murali Yallapu   +2 more
exaly   +1 more source

Recombinant subunit vaccines

Current Opinion in Biotechnology, 1991
Research that may lead to the development of recombinant DNA-based vaccines has been conducted on a broad front. This has resulted in an increased understanding of immunological responsiveness to vaccines, the rational engineering of immunogens, and new means of delivering vaccines.
openaire   +2 more sources