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Adjuvants and Subunit Vaccines
20101 Adjuvants 2 Subunit Vaccines 3 Acknowledgments Keywords: adjuvants and subunit vaccines; immunological phenomena-triggered by vaccine adjuvants; antigen-presenting cells (APC)-activation and expansion of antigen-specific T- and B-cell populations.; new vaccine adjuvants; adjuvants licensed for use in humans, MF59; bacterial ...
Giuseppe Del Giudice, Rino Rappuoli
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Potency of a Scalable Nanoparticulate Subunit Vaccine
Nano Letters, 2018Nanoparticulate vaccines can potentiate immune responses by site-specific drainage to lymph nodes (LNs). This approach may benefit from a nanoparticle engineering method with fine control over size and codelivery of antigen and adjuvant. Here, we applied the flash nanocomplexation (FNC) method to prepare nanovaccines via polyelectrolyte complexation of
Dongdong Qiao +7 more
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Clinical Trial of a Subunit Influenza Vaccine
Scandinavian Journal of Infectious Diseases, 1981A double-blind field trial was performed comparing a subunit influenza vaccine (A/Victoria/75 and B/Hongkong/73) with placebo. A good protection against influenza was induced by the vaccine. On the basis of serological determinations (enzyme immunoassay, EIA) the incidences of influenza A and B infections were reduced within a period from 3 weeks up to
S, Pyrhönen, J, Suni, M, Romo
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Vaccine, 2012
Genetic immunization holds promise as a vaccination method, but has so far proven ineffective in large primate and human trials. Herein, we examined the relative merits of genetic immunization and peptide immunization using bacteriophage λ. Bacteriophage λ has proven effective in immune challenge models using both immunization methods, but there has ...
Brad S, Thomas +8 more
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Genetic immunization holds promise as a vaccination method, but has so far proven ineffective in large primate and human trials. Herein, we examined the relative merits of genetic immunization and peptide immunization using bacteriophage λ. Bacteriophage λ has proven effective in immune challenge models using both immunization methods, but there has ...
Brad S, Thomas +8 more
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The case for a subunit vaccine against malaria
Trends in Parasitology, 2011New technologies and some disillusionment with subunit vaccines has led to increased interest in the development of whole parasite vaccines for malaria. Instead, the current priority should be to build on the partial success of the recombinant protein sporozoite vaccine, RTS,S.
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Targeting the Mannose Receptor with Mannosylated Subunit Vaccines
Current Medicinal Chemistry, 2014The mannose receptor (MR) is an important component of the immune system and understanding the structural and conformational characteristics of this receptor is a key aspect of vaccine design. Improved understanding of the role of carbohydrate recognition domains 4-7 (CRDs 4-7) in recognising glycosylated ligands present on the surface of pathogens ...
Sedaghat, B., Stephenson, R., Toth, I.
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[Tolerance of preventive influenza vaccination with a subunit vaccine].
Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)), 1994The frequency and intensity of undesirable side effects after protective vaccination against influenza with a commercially available vaccine were studied. 82 gainfully employed persons of both sexes were questioned in respect of local reactions such as weal and flare reactions, itching, sensation of heat, tenderness on pressure, and impeded movement ...
T A, Wagner, R, Skiba
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2015
Subunit vaccine delivery , Subunit vaccine delivery , کتابخانه مرکزی دانشگاه علوم پزشکی ...
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Subunit vaccine delivery , Subunit vaccine delivery , کتابخانه مرکزی دانشگاه علوم پزشکی ...
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[Polysaccharide subunit vaccines].
La Revue du praticien, 1995The polysaccharide capsules of many germs (pneumococcus, meningococcus, Haemophilus b, salmonella, etc.) can induce synthesis of protective antibodies in man. The development of many vaccines has been based on this phenomenon. Unfortunately, the polysaccharide antigens cannot trigger an immune response before the age of 2 years.
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