Results 31 to 40 of about 21,681 (186)

Spatial and Sex-Dependent Responses of Adult Endogenous Neural Stem Cells to Alcohol Consumption

Stem Cell Reports, 2017
Summary: Chronic alcohol abuse results in alcohol-related neurodegeneration, and critical gaps in our knowledge hinder therapeutic development. Neural stem cells (NSCs) are a subpopulation of cells within the adult brain that contribute to brain ...
Erica L. McGrath, Junling Gao, Yong-Fang Kuo, Tiffany J. Dunn, Moniqua J. Ray, Kelly T. Dineley, Kathryn A. Cunningham, Bhupendra S. Kaphalia, Ping Wu   +8 more
doaj   +1 more source

Organization of the ventricular zone of the cerebellum

Frontiers in Cellular Neuroscience, 2022
The roof of the fourth ventricle (4V) is located on the ventral part of the cerebellum, a region with abundant vascularization and cell heterogeneity that includes tanycyte-like cells that define a peculiar glial niche known as ventromedial cord.
Gabriela B. Gómez-González, Marymar Becerra-González, Marianne Lizeth Martínez-Mendoza, Cynthia Alejandra Rodríguez-Arzate, Ataúlfo Martínez-Torres   +4 more
doaj   +1 more source

Expression of the Ubiquitin Ligase HRD1 in Neural Stem/Progenitor Cells of the Adult Mouse Brain

Journal of Pharmacological Sciences, 2011
.: Neural stem/progenitor cells (NSCs) reside in the subventricular zone (SVZ) and subgranular zone of the hippocampal dentate gyrus in adult mammals. The ubiquitin ligase HRD1 is associated with degradation of amyloid precursor protein and believed to ...
Koichi Kawada, Masayuki Kaneko, Yasuyuki Nomura, Seisuke Mimori, Hiroshi Hamana, Kiyokazu Ogita, Toshihiko Murayama, Hiromichi Fujino, Yasunobu Okuma   +8 more
doaj   +1 more source

Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinson's disease. [PDF]

PLoS ONE, 2012
Cells of the neural stem cell lineage in the adult subventricular zone (SVZ) respond to brain insult by increasing their numbers and migrating through the rostral migratory stream.
Xuefeng Jing, Hideto Miwa, Takahiro Sawada, Ichiro Nakanishi, Tomoyoshi Kondo, Masayasu Miyajima, Kazushige Sakaguchi   +6 more
doaj   +1 more source

The Postnatal Subventricular Zone: A Source of New Cells in This Old Brain

Nepal Journal of Neuroscience, 2005
Findings over the past decades demonstrating persistent neurogenesis in the adult brain have challenged the view of a fixed circuitry and raise hopes for self-renewal following brain injury.
Angélique Bordey
doaj   +1 more source

The role of inflammation in subventricular zone cancer [PDF]

Progress in Neurobiology, 2018
The adult subventricular zone (SVZ) stem cell niche has proven vital for discovering neurodevelopmental mechanisms and holds great potential in medicine for neurodegenerative diseases. Yet the SVZ holds a dark side - it can become tumorigenic. Glioblastomas can arise from the SVZ via cancer stem cells (CSCs).
Bardella, C, Al-Shammari, A, Soares, L, Tomlinson, I, O'Neill, E, Szele, F   +5 more
openaire   +2 more sources

Ischemic stroke and neurogenesis in the subventricular zone [PDF]

Neuropharmacology, 2008
The subventricular zone (SVZ) of the lateral ventricle contains neural stem and progenitor cells that generate neuroblasts, which migrate to the olfactory bulb where they differentiate into interneurons. Ischemic stroke induces neurogenesis in the SVZ and these cells migrate to the boundary of the ischemic lesion.
Rui Lan, Zhang, Zheng Gang, Zhang, Michael, Chopp   +2 more
openaire   +2 more sources

Copper Modulates Adult Neurogenesis in Brain Subventricular Zone

International Journal of Molecular Sciences, 2022
The subventricular zone (SVZ) in lateral ventricles is the largest neurogenic region in adult brain containing high amounts of copper (Cu). This study aims to define the role of Cu in adult neurogenesis by chelating labile Cu ions using a well-established Cu chelator D-Penicillamine (D-Pen).
Luke L. Liu, Richard M. van Rijn, Wei Zheng   +2 more
openaire   +2 more sources

Tcf7L2 is essential for neurogenesis in the developing mouse neocortex

Neural Development, 2018
Generation of neurons in the embryonic neocortex is a balanced process of proliferation and differentiation of neuronal progenitor cells. Canonical Wnt signalling is crucial for expansion of radial glial cells in the ventricular zone and for ...
Olga Chodelkova, Jan Masek, Vladimir Korinek, Zbynek Kozmik, Ondrej Machon   +4 more
doaj   +1 more source

Neuropeptide Y Promotes Neurogenesis in Murine Subventricular Zone [PDF]

Stem Cells, 2008
Abstract Stem cells of the subventricular zone (SVZ) represent a reliable source of neurons for cell replacement. Neuropeptide Y (NPY) promotes neurogenesis in the hippocampal subgranular layer and the olfactory epithelium and may be useful for the stimulation of SVZ dynamic in brain repair purposes.
Agasse, Fabienne, Bernardino, Liliana, Kristiansen, Heidi, Christiansen, Søren H, Ferreira, Raquel, Silva, Bruno, Grade, Sofia, Woldbye, David P D, Malva, João O   +8 more
openaire   +3 more sources