Results 101 to 110 of about 48,643 (286)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Universal Approximation with Deep Narrow Networks
, 2020 The classical Universal Approximation Theorem holds for neural networks of arbitrary width and bounded depth. Here we consider the natural `dual' scenario for networks of bounded width and arbitrary depth.
Kidger, Patrick, Lyons, Terry
core
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
High Speed Comparator Design for the Implementation of Successive Approximation Register ADC
2019 3rd International Symposium on Multidisciplinary Studies and Innovative Technologies (ISMSIT), 2019 In this work, a comparator operating at 400MHz frequency with a resolution of 10 bits is designed. In order to eliminate the effect of offset voltage in the designed comparator circuit, auto-zero technique is used. The fully differential operational amplifier structure is used in the comparator circuit as it prevents common mode distortion.
openaire +3 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
New and Accurate Online Self-Test Methods for Gain and Offset Errors of 10-Bit SAR-ADC
Journal of Electrical and Computer EngineeringThe absolute quantization range of the successive approximation register (SAR) ADC is impacted by nonideality parameters like offset and gain error, which can make its performance at a lower level in high resolution applications.
Mohammed Abdulmahdi Mohammedali +1 more
doaj +1 more source
Electronics Letters, 2019 A resolution‐reconfigurable, bandwidth‐scalable analogue‐to‐digital converter (ADC) with programmable‐gain (PG) functionality for a multi‐sensor system, which encompasses various signals such as bio‐signals and battery‐level, is presented.
J. Rhee, S. Kim
doaj +1 more source